Search Results - "SONG, Byeongwoon"

The Cholesterol Transport Inhibitor U18666A Interferes with Pseudorabies Virus Infection by Song, Byeongwoon

“…Many viruses require the maintenance of lysosomal cholesterol homeostasis for a successful infection; however, the role of lysosomal cholesterol homeostasis in…”
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Cyclodextrins: Assessing the Impact of Cavity Size, Occupancy, and Substitutions on Cytotoxicity and Cholesterol Homeostasis by Szente, Lajos, Singhal, Ashutosh, Domokos, Andras, Song, Byeongwoon

“…Cyclodextrins (CDs) are cyclic oligosaccharides; the most common CDs contain six, seven, or eight glucose units called α-CDs, β-CDs, and γ-CDs, respectively…”
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Bafilomycin A1 Inhibits HIV-1 Infection by Disrupting Lysosomal Cholesterol Transport by Song, Byeongwoon, Korolkova, Olga

“…The productive replication of human immunodeficiency virus type 1 (HIV-1) involves intricate interactions between viral proteins and host cell machinery…”
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2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy by Singhal, Ashutosh, Krystofiak, Evan S., Jerome, W. Gray, Song, Byeongwoon

“…Niemann-Pick type C (NPC) disease is a fatal neurodegenerative disorder caused by mutations in NPC1 and NPC2 genes that result in an accumulation of…”
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Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann–Pick C1 mutant cell via lysosome-associated membrane protein 1 by Singhal, Ashutosh, Szente, Lajos, Hildreth, James E. K., Song, Byeongwoon

“…Niemann–Pick type C (NPC) disease is a fatal hereditary neurodegenerative disorder characterized by a massive accumulation of cholesterol in lysosomes and late…”
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Specific Recognition and Accelerated Uncoating of Retroviral Capsids by the TRIM5α Restriction Factor by Stremlau, Matthew, Perron, Michel, Lee, Mark, Li, Yuan, Song, Byeongwoon, Javanbakht, Hassan, Diaz-Griffero, Felipe, Anderson, Donovan J., Sundquist, Wesley I., Sodroski, Joseph

“…The host restriction factor TRIM5a mediates species-specific, early blocks to retrovirus infection; susceptibility to these blocks is determined by viral…”
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TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1 by Lee, Younglang, Song, Byeongwoon, Park, Chankyu, Kwon, Ki-Sun

“…The innate immune response is a host defense mechanism against infection by viruses and bacteria. Type I interferons (IFNα/β) play a crucial role in innate…”
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Retrovirus Restriction by TRIM5α Variants from Old World and New World Primates by SONG, Byeongwoon, JAVANBAKHT, Hassan, PERRON, Michel, DO HYUN PARK, STREMLAU, Matthew, SODROSKI, Joseph

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The B30.2(SPRY) Domain of the Retroviral Restriction Factor TRIM5α Exhibits Lineage-Specific Length and Sequence Variation in Primates by SONG, Byeongwoon, GOLD, Bert, O'HUIGIN, Colm, JAVANBAKHT, Hassan, XING LI, STREMLAU, Matthew, WINKLER, Cheryl, DEAN, Michael, SODROSKIL, Joseph

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The Human TRIM5α Restriction Factor Mediates Accelerated Uncoating of the N-Tropic Murine Leukemia Virus Capsid by PERRON, Michel J, STREMLAU, Matthew, LEE, Mark, JAVANBAKHT, Hassan, SONG, Byeongwoon, SODROSKI, Joseph

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TRIM5α Mediates the Postentry Block to N-Tropic Murine Leukemia Viruses in Human Cells by Perron, Michel J., Stremlau, Matthew, Song, Byeongwoon, Ulm, Wes, Mulligan, Richard C., Sodroski, Joseph, Coffin, John M.

“…Murine leukemia viruses (MLVs) have been classified as N-tropic (N-MLV) or B-tropic (B-MLV), depending on their ability to infect particular mouse strains. The…”
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Virus-Specific Effects of TRIM5αrh RING Domain Functions on Restriction of Retroviruses by Li, Xing, Kim, Jonghwa, Song, Byeongwoon, Finzi, Andrés, Pacheco, Beatriz, Sodroski, Joseph

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TRIM32 Protein Sensitizes Cells to Tumor Necrosis Factor (TNFα)-induced Apoptosis via Its RING Domain-dependent E3 Ligase Activity against X-linked Inhibitor of Apoptosis (XIAP) by Ryu, Yeung Sook, Lee, Younglang, Lee, Keun Woo, Hwang, Chae Young, Maeng, Jin-Soo, Kim, Jeong-Hoon, Seo, Yeon-Soo, You, Kwan-Hee, Song, Byeongwoon, Kwon, Ki-Sun

“…TRIM32, which belongs to the tripartite motif (TRIM) protein family, has the RING finger, B-box, and coiled-coil domain structures common to this protein…”
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Retroviral Restriction Factor TRIM5α Is a Trimer by MISCHE, Claudia C, JAVANBAKHT, Hassan, SONG, Byeongwoon, DIAZ-GRIFFERO, Felipe, STREMLAU, Matthew, STRACK, Bettina, ZHIHAI SI, SODROSKI, Joseph

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Functional Replacement of the RING, B-Box 2, and Coiled-Coil Domains of Tripartite Motif 5α (TRIM5α) by Heterologous TRIM Domains by XING LI, YUAN LI, STREMLAU, Matthew, WEN YUAN, SONG, Byeongwoon, PERRON, Michel, SODROSKI, Joseph

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Binding and Susceptibility to Postentry Restriction Factors in Monkey Cells Are Specified by Distinct Regions of the Human Immunodeficiency Virus Type 1 Capsid by OWENS, Christopher M, SONG, Byeongwoon, PERRON, Michel J, YANG, Peter C, STREMLAU, Matthew, SODROSKI, Joseph

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Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection by Si, Z, Vandegraaff, N, O'hUigin, C, Song, B, Yuan, W, Xu, C, Perron, M, Li, X, Marasco, W.A, Engelman, A

“…Primate tripartite motif 5α (TRIM5α) proteins mediate innate intracellular resistance to retroviruses. In humans, TRIM5 is located in a paralogous cluster that…”
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The ability of multimerized cyclophilin A to restrict retrovirus infection by Javanbakht, Hassan, Diaz-Griffero, Felipe, Yuan, Wen, Yeung, Darwin F, Li, Xing, Song, Byeongwoon, Sodroski, Joseph

“…Abstract In owl monkeys, the typical retroviral restriction factor of primates, TRIM5α, is replaced by TRIMCyp. TRIMCyp consists of the TRIM5 RING, B-box 2 and…”
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Lysosome‐Associated Membrane Protein 1 Rescues Cholesterol Accumulation in NPC1 Mutant Cell by Enhancing Lysosome‐ER Contacts by Singhal, Ashutosh, Song, Byeongwoon

“…Niemann‐Pick type C (NPC) disease is a neurodegenerative disorder caused by mutations in NPC1 or NPC2 gene, encoding a lysosomal membrane and luminal protein,…”
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Distinct host cell proteins incorporated by SIV replicating in CD4+ T cells from natural disease resistant versus non-natural disease susceptible hosts by Stephenson, Susan T, Bostik, Pavel, Song, Byeongwoon, Rajan, Devi, Bhimani, Samrath, Rehulka, Pavel, Mayne, Ann E, Ansari, Aftab A

“…Enveloped viruses including the simian immunodeficiency virus (SIV) replicating within host cells acquire host proteins upon egress from the host cells. A…”
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