Search Results - "SONCIN, Fabrice"

miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons by Villain, Gaëlle, Poissonnier, Loïc, Noueihed, Baraa, Bonfils, Gaëlle, Rivera, Jose Carlos, Chemtob, Sylvain, Soncin, Fabrice, Mattot, Virginie

“…MicroRNAs are key regulators of angiogenesis, as illustrated by the vascular defects observed in miR-126-deficient animals. The miR-126 duplex gives rise to…”
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RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non-Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway by Dubois, Fatéméh, Keller, Maureen, Calvayrac, Olivier, Soncin, Fabrice, Hoa, Lily, Hergovich, Alexander, Parrini, Maria-Carla, Mazières, Julien, Vaisse-Lesteven, Mélissa, Camonis, Jacques, Levallet, Guénaëlle, Zalcman, Gérard

“…Inactivation of the tumor suppressor gene RASSF1A by promoter hypermethylation represents a key event underlying the initiation and progression of lung cancer…”
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Endothelial Cell Activation Is Regulated by Epidermal Growth Factor-like Domain 7 (Egfl7) during Inflammation by Pinte, Sébastien, Caetano, Bertrand, Le Bras, Alexandra, Havet, Chantal, Villain, Gaëlle, Dernayka, Racha, Duez, Catherine, Mattot, Virginie, Soncin, Fabrice

“…Activation of the blood vessel endothelium is a critical step during inflammation. Endothelial cells stimulated by pro-inflammatory cytokines play an essential…”
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The impact of macrophages on endothelial cells is potentiated by cycling hypoxia: Enhanced tumor inflammation and metastasis by Delprat, Victor, Huart, Camille, Feron, Olivier, Soncin, Fabrice, Michiels, Carine

“…Cycling hypoxia (cyH), neo-angiogenesis, and tumor-associated macrophages are key features of the tumor microenvironment. In this study, we demonstrate that…”
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A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs by Pauty, Joris, Usuba, Ryo, Cheng, Irene Gayi, Hespel, Louise, Takahashi, Haruko, Kato, Keisuke, Kobayashi, Masayoshi, Nakajima, Hiroyuki, Lee, Eujin, Yger, Florian, Soncin, Fabrice, Matsunaga, Yukiko T.

“…Angiogenesis is the formation of new capillaries from pre-existing blood vessels and participates in proper vasculature development. In pathological conditions…”
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Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform by Messelmani, Taha, Le Goff, Anne, Soncin, Fabrice, Souguir, Zied, Merlier, Franck, Maubon, Nathalie, Legallais, Cécile, Leclerc, Eric, Jellali, Rachid

“…The liver is one of the main organs involved in the metabolism of xenobiotics and a key organ in toxicity studies. Prior to accessing the hepatocytes,…”
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Genes Involved in miRNA Biogenesis Are Not Downregulated in SARS-CoV-2 Infection by Garnier, Nathalie, Sane, Famara, Massara, Layal, Soncin, Fabrice, Gosset, Philippe, Hober, Didier, Szunerits, Sabine, Engelmann, Ilka

“…miRNAs, small non-coding RNAs that regulate gene expression, are involved in various pathological processes, including viral infections. Virus infections may…”
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Egfl7 Promotes Tumor Escape from Immunity by Repressing Endothelial Cell Activation by DELFORTRIE, Suzanne, PINTE, Sébastien, FAVEEUW, Christelle, SONCIN, Fabrice, MATTOT, Virginie, SAMSON, Chantal, VILLAIN, Gaëlle, CAETANO, Bertrand, LAURIDANT-PHILIPPIN, Géraldine, BARANZELLI, Marie-Christine, BONNETERRE, Jacques, TROTTEIN, François

“…Downregulating the leukocyte adhesion molecules expressed by endothelial cells that line tumor blood vessels can limit the entry of immune effector cells into…”
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IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein by Gaggero, Silvia, Martinez-Fabregas, Jonathan, Cozzani, Adeline, Fyfe, Paul K, Leprohon, Malo, Yang, Jie, Thomasen, F Emil, Winkelmann, Hauke, Magnez, Romain, Conti, Alberto G, Wilmes, Stephan, Pohler, Elizabeth, van Gijsel Bonnello, Manuel, Thuru, Xavier, Quesnel, Bruno, Soncin, Fabrice, Piehler, Jacob, Lindorff-Larsen, Kresten, Roychoudhuri, Rahul, Moraga, Ignacio, Mitra, Suman

“…Cytokines interact with their receptors in the extracellular space to control immune responses. How the physicochemical properties of the extracellular space…”
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Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells by Danoy, Mathieu, Jellali, Rachid, Tauran, Yannick, Bruce, Johanna, Leduc, Marjorie, Gilard, Françoise, Gakière, Bertrand, Scheidecker, Benedikt, Kido, Taketomo, Miyajima, Atsushi, Soncin, Fabrice, Sakai, Yasuyuki, Leclerc, Eric

“…The liver is a complex organ composed of several cell types organized hierarchically. Among these, liver sinusoidal endothelial cells (LSECs) are specialized…”
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Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor by Thirant, Cécile, Galan-Moya, Eva-Maria, Dubois, Luiz Gustavo, Pinte, Sébastien, Chafey, Philippe, Broussard, Cédric, Varlet, Pascale, Devaux, Bertrand, Soncin, Fabrice, Gavard, Julie, Junier, Marie-Pierre, Chneiweiss, Hervé

“…Presence in glioblastomas of cancer cells with normal neural stem cell (NSC) properties, tumor initiating capacity, and resistance to current therapies…”
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Multi-Layered Human Blood Vessels-on-Chip Design Using Double Viscous Finger Patterning by Delannoy, Elise, Tellier, Géraldine, Cholet, Juliette, Leroy, Alice M, Treizebré, Anthony, Soncin, Fabrice

“…Blood vessel-on-a-chip models aim at reproducing vascular functions. However, very few efficient methods have been designed to address the need for biological…”
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Egfl7 is differentially expressed in arteries and veins during retinal vascular development by Poissonnier, Loïc, Villain, Gaëlle, Soncin, Fabrice, Mattot, Virginie

“…The vasculature of the central nervous system (CNS) is composed of vascular endothelial and mural cells which interact closely with glial cells and neurons…”
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Bone morphogenic proteins are overexpressed in malignant melanoma and promote cell invasion and migration by ROTHHAMMER, Tanja, POSER, Ina, SONCIN, Fabrice, BATAILLE, Frauke, MOSER, Markus, BOSSERHOFF, Anja-Katrin

“…Malignant melanoma cells are known to have altered expression of growth factors compared with normal human melanocytes. These changes probably favor tumor…”
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Altered microRNA expression in severe COVID‐19: Potential prognostic and pathophysiological role by Garnier, Nathalie, Pollet, Kato, Fourcot, Marie, Caplan, Morgan, Marot, Guillemette, Goutay, Julien, Labreuche, Julien, Soncin, Fabrice, Boukherroub, Rabah, Hober, Didier, Szunerits, Sabine, Poissy, Julien, Engelmann, Ilka

“…Benjamini-Hochberg false discovery rate correction Of the miRNAs found of interest to discriminate between severe and non-severe COVID-19 in our study, some…”
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Egfl7 promotes tumor escape from immunity by Pinte, Sébastien, Soncin, Fabrice

“…Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by…”
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Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses by Ghinnagow, Reem, De Meester, Julie, Cruz, Luis Javier, Aspord, Caroline, Corgnac, Stéphanie, Macho-Fernandez, Elodie, Soulard, Daphnée, Fontaine, Josette, Chaperot, Laurence, Charles, Julie, Soncin, Fabrice, Mami-Chouaib, Fathia, Plumas, Joel, Faveeuw, Christelle, Trottein, François

“…Vaccines designed to abrogate the tolerance of tumor self-antigens and amplify cytotoxic CD8 + T cells (CTLs) have promise for the treatment of cancer. Type I…”
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Ets-1 expression promotes epithelial cell transformation by inducing migration, invasion and anchorage-independent growth by HAHNE, Jens Claus, OKUDUCU, Ali Fuat, KAMINSKI, Annette, FLORIN, Alexandra, SONCIN, Fabrice, WERNERT, Nicolas

“…Ets-1 is the prototype of the family of ETS transcription factors. In human tumors, Ets-1 is expressed in endothelial cells and fibroblasts of the tumor stroma…”
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VE-statin/egfl7 expression in endothelial cells is regulated by a distal enhancer and a proximal promoter under the direct control of Erg and GATA-2 by Le Bras, Alexandra, Samson, Chantal, Trentini, Matteo, Caetano, Bertrand, Lelievre, Etienne, Mattot, Virginie, Beermann, Friedrich, Soncin, Fabrice

“…Angiogenesis is the process by which new blood vessels arise from existing ones by the budding out of endothelial cell capillaries from the luminal side of…”
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Sequential Phosphorylation by Mitogen-activated Protein Kinase and Glycogen Synthase Kinase 3 Represses Transcriptional Activation by Heat Shock Factor-1 by Chu, Boyang, Soncin, Fabrice, Price, Brendan D., Stevenson, Mary Ann, Calderwood, Stuart K.

“…Mammalian heat shock genes are regulated at the transcriptional level by heat shock factor-1 (HSF-1), a sequence-specific transcription factor. We have…”
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