Search Results - "SOMBERG, John C"

Evaluation of the Effects of Different Energy Drinks and Coffee on Endothelial Function by Molnar, Janos, MD, Somberg, John C., MD

“…Endothelial function plays an important role in circulatory physiology. There has been differing reports on the effect of energy drink on endothelial function…”
Get full text

Assessment of Cardiovascular and Noncardiovascular Medical Device Recalls by Somberg, John C., MD, McEwen, Pauline, MD, Molnar, Janos, MD

“…Medical device recalls have called attention to the device approval process in the United States. The premarket approval (PMA) process requires clinical trials…”
Get full text

Van Gogh and Digitalis by Somberg, John C.

“…Digitalis can cause direct cardiotoxicity, but the neuroexcitatory effects of digitalis and sympathetic/parasympathetic activity arising from activation of the…”
Get full text

The clinical pharmacology of ethacrynic acid by Molnar, Janos, Somberg, John C

“…Ethacrynic acid (Edecrin) is a loop diuretic that produces a prompt and profound diuresis. The primary action of ethacrynic acid is the inhibition of the…”
Get full text

The Extrapolation of Study Results in the Device Approval Process by Somberg, John C., MD

Get full text

Usefulness of QT dispersion as an electrocardiographically derived index by Somberg, John C, Molnar, Janos

“…One way to assess increased dispersion of ventricular repolarization is the measurement of QT dispersion. Somberg diecusses the usefulness of QT dispersion as…”
Get full text

Intravenous Sotalol for the Treatment of Ventricular Dysrhythmias in an Infant on Extracorporeal Membrane Oxygenation by Jacobson, Jessica L., Somberg, John C., Nguyen, Hoang H.

“…Sotalol is a class III anti-arrhythmic agent with beta receptor blocking properties. Intravenous (IV) sotalol may be useful to treat refractory atrial and…”
Get full text

Model-Informed Development of Sotalol Loading and Dose Escalation Employing an Intravenous Infusion by Somberg, John C, Vinks, Alexander A, Dong, Min, Molnar, Janos

“…Sotalol is often employed to prevent recurrence of symptomatic atrial flutter/atrial fibrillation. Because sotalol can prolong the QT interval excessively…”
Get full text

Retrospective Study on the Analgesic Activity of a Topical (TT-CTAC) Cream in Patients With Diabetic Neuropathy and Other Chronic Pain Conditions by Somberg, John C, Molnar, Janos

“…Treatment of chronic pain in diabetic neuropathy or neuropathic pain of other origins is challenging. Compounded topical formulations have evolved as potential…”
Get full text

Digoxin therapy for atrial fibrillation in the twenty-first century by Somberg, John C

Get full text

The new year by Somberg, John C

Get full text

The failing Ebola policy by Somberg, John C

Get full text

Efficacy of Intravenous and Oral Sotalol in Pharmacologic Conversion of Atrial Fibrillation: A Systematic Review and Meta-Analysis by Milan, David J, Saul, J Philip, Somberg, John C, Molnar, Janos

“…The role of sotalol is well established for the maintenance of sinus rhythm after successful conversion of atrial fibrillation (AF). However, its role in…”
Get more information

Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol by Shugg, Tyler, Somberg, John C., Molnar, Janos, Overholser, Brian R.

“…The clinical utility of intravenous sotalol is limited due to an extended half-life combined with the potential to generate life-threatening arrhythmias. The…”
Get full text

Differential effect of glyburide ( glibenclamide) and metformin on qt dispersion: a potential adenosine triphosphate sensitive k+ channel effect by Najeed, Syed A, Khan, Ijaz A, Molnar, Janos, Somberg, John C

“…Glyburide (glibenclamide) is a specific blocker of the adenosine triphosphate (ATP) sensitive potassium (K+) channel. It has been reported to result in…”
Get full text

A Rapid Method to Evaluate Cardiac Repolarization Changes: The Effect of Two Coffee Strengths on the QT Interval by Molnar, Janos, Somberg, John C

“…To assess the effect of coffee on ventricular repolarization as measured by an electrocardiogram. Fifty-four healthy volunteers (34 males and 20 females, age…”
Get more information

Guidelines for a new year by Somberg, John C

Get full text

Retrospective Evaluation on the Analgesic Activities of 2 Compounded Topical Creams and Voltaren Gel in Chronic Noncancer Pain by Somberg, John C, Molnar, Janos

“…Pharmacologic treatment of chronic pain is challenging. Oral therapy may require multiple medications; each has side effects, dose limitations, and limited…”
Get full text

A perspective on the support of scientific research by Somberg, John C

Get full text

The cart before the horse by Somberg, John C

Get full text