Search Results - "SOLTYS, Stephen"

Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector by Grieger, Joshua C, Soltys, Stephen M, Samulski, Richard Jude

“…Adeno-associated virus (AAV) has shown great promise as a gene therapy vector in multiple aspects of preclinical and clinical applications. Many developments…”
Get full text

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection by Zincarelli, Carmela, Soltys, Stephen, Rengo, Giuseppe, Rabinowitz, Joseph E

“…This study examines transgene expression and biodistribution of adeno-associated virus (AAV) pseudotyped 1–9 after tail vein (TV) injection in male mice. Using…”
Get full text

An association of intrapartum synthetic oxytocin dosing and the odds of developing autism by Soltys, Stephen M, Scherbel, Jill Rose, Kurian, Joseph R, Diebold, Todd, Wilson, Teresa, Hedden, Lindsay, Groesch, Kathleen, Diaz-Sylvester, Paula L, Botchway, Albert, Campbell, Pamela, Loret de Mola, Julio Ricardo

“…A case-control study was performed to determine whether an association exists between exposure to synthetic oxytocin and a subsequent autism spectrum disorder…”
Get full text

adrenal β-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo by Lymperopoulos, Anastasios, Rengo, Giuseppe, Zincarelli, Carmela, Kim, Jihee, Soltys, Stephen, Koch, Walter J

“…Aldosterone produces a multitude of effects in vivo, including promotion of postmyocardial infarction adverse cardiac remodeling and heart failure progression…”
Get full text

Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue by PLEGER, Sven T, MOST, Patrick, KATUS, Hugo A, ECKHART, Andrea D, RABINOWITZ, Joseph E, KOCH, Walter J, BOUCHER, Matthieu, SOLTYS, Stephen, KURT CHUPRUN, J, PLEGER, Wiebke, ERHE GAO, DASGUPTA, Abhijit, RENGO, Giuseppe, REMPPIS, Andrew

“…The incidence of heart failure is ever-growing, and it is urgent to develop improved treatments. An attractive approach is gene therapy; however, the clinical…”
Get full text

Targeted Inhibition of Cardiomyocyte Gi Signaling Enhances Susceptibility to Apoptotic Cell Death in Response to Ischemic Stress by DEGEORGE, Brent R, ERHE GAO, ECKHART, Andrea D, KOCH, Walter J, BOUCHER, Matthieu, VINGE, Leif E, MARTINI, Jeffrey S, RAAKE, Philip W, CHUPRUN, J. Kurt, HARRIS, David M, KIM, Gilbert W, SOLTYS, Stephen

“…A salient characteristic of dysfunctional myocardium progressing to heart failure is an upregulation of the adenylyl cyclase inhibitory guanine nucleotide (G)…”
Get full text

The self-directed, structured summary as a teaching tool in a psychiatry journal club by Dzara, Kristina, Jain, Gaurav, Soltys, Stephen M

“…[...]a self-directed, structured summary format was incorporated to standardize the curriculum, clarify methodology, and increase critical appraisal skills…”
Get full text

A case of excessive weight gain with guanfacine extended release: 9.53 kg in 4 weeks by Khan, Mehnaz A, Jain, Gaurav, Soltys, Stephen M, Takahashi, Ayame

Get more information

The Self-Directed, Structured Summary as a Teaching Tool in a PsychiatryJournal Club by Dzara, Kristina, Jain, Gaurav, Soltys, Stephen M.

Get full text

Primer for the Interim Chair by Soltys, Stephen M.

“…Objective Being successful in the role of an Interim Chair requires an approach to transitional leadership that is different from that of individuals filling…”
Get full text

Transitioning Between Clerkship Directors by Soltys, Stephen M., Pary, Robert J., Robinson, Stephen W., Markwell, Stephen J.

“…Objective The authors report on succession-planning for mid-level academic positions. Method The authors describe the process of succession-planning between…”
Get full text

Do-Not-Resuscitate Orders in Suicidal Patients: Clinical, Ethical, and Legal Dilemmas by Cook, Renee, D.O, Pan, Philip, M.D, Silverman, Ross, J.D, Soltys, Stephen M., M.D

“…Background The authors review the literature related to patients who obtain a Do-Not-Resuscitate (DNR) order in preparation for a suicide attempt. Objective…”
Get full text

Do-not-resuscitate orders in suicidal patients: clinical, ethical, and legal dilemmas by Cook, Renee, Pan, Philip, Silverman, Ross, Soltys, Stephen M

“…BACKGROUNDThe authors review the literature related to patients who obtain a Do-Not-Resuscitate (DNR) order in preparation for a suicide attempt.OBJECTIVEThe…”
Get full text

3.33 Is Intrapartum Epidural Anesthesia Associated With Increased Synthetic Oxytocin Exposure and ASD? by Soltys, Stephen M., Wilson, Teresa S., Botchway, Albert, Groesch, Kathleen, Diaz-Sylvester, Paula L., Riva, Stephanie Dalla, Campbell, Pamela, Loret de Mola, Julio Ricardo

Get full text

Myocardial Adeno-Associated Virus Serotype 6-βARKct Gene Therapy Improves Cardiac Function and Normalizes the Neurohormonal Axis in Chronic Heart Failure by RENGO, Giuseppe, LYMPEROPOULOS, Anastasios, ZINCARELLI, Carmela, DONNIACUO, Maria, SOLTYS, Stephen, RABINOWITZ, Joseph E, KOCH, Walter J

“…Background— The upregulation of G protein–coupled receptor kinase 2 in failing myocardium appears to contribute to dysfunctional β-adrenergic receptor (βAR)…”
Get full text

Modulation of Adrenal Catecholamine Secretion by In Vivo Gene Transfer and Manipulation of G Protein–coupled Receptor Kinase-2 Activity by Lymperopoulos, Anastasios, Rengo, Giuseppe, Zincarelli, Carmela, Soltys, Stephen, Koch, Walter J

“…We recently reported that the upregulation of adrenal G protein–coupled receptor kinase-2 (GRK2) causes enhanced catecholamine (CA) secretion by desensitizing…”
Get full text

Comparative Cardiac Gene Delivery of Adeno-Associated Virus Serotypes 1-9 reveals that AAV6 Mediates the Most Efficient Transduction in Mouse Heart by Zincarelli, Carmela, Soltys, Stephen, Rengo, Giuseppe, Koch, Walter J., Rabinowitz, Joseph E.

“…Cardiac gene transfer is an attractive tool for developing novel heart disease treatments. Adeno‐associated viral (AAV) vectors are widely used to mediate…”
Get full text

Nonadherence to medication in hypothyroidism: a case report by Kandukuri, Rajeev C, Khan, Mehnaz A, Soltys, Stephen M

“…This case report reviews the consequences of nonadherence to a hypothyroidism medication schedule and examines the complexity of hypothyroidism treatment. Both…”
Get full text

Perceived family and social support: impact on children by Kashani, J H, Canfield, L A, Borduin, C M, Soltys, S M, Reid, J C

“…The purpose of this study was to investigate the relation of children's perceived family and social support to their behavior and hopelessness. Subjects were…”
Get more information

Correlates of anxiety in psychiatrically hospitalized children and their parents by Kashani, J H, Vaidya, A F, Soltys, S M, Dandoy, A C, Katz, L M, Reid, J C

“…The authors separated 100 children hospitalized in a child psychiatry service into three groups according to their level of anxiety on the basis of the…”
Get more information