Search Results - "SOLDANO, STEFANO"

Macrophage M1/M2 polarization and rheumatoid arthritis: A systematic review by Tardito, Samuele, Martinelli, Giulia, Soldano, Stefano, Paolino, Sabrina, Pacini, Greta, Patane, Massimo, Alessandri, Elisa, Smith, Vanessa, Cutolo, Maurizio

“…Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease; the clinical manifestations are correlated with continuum multiarticular synovitis,…”
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The Role of M1/M2 Macrophage Polarization in Rheumatoid Arthritis Synovitis by Cutolo, Maurizio, Campitiello, Rosanna, Gotelli, Emanuele, Soldano, Stefano

“…Innate and adaptive immunity represent a harmonic counterbalanced system involved in the induction, progression, and possibly resolution of the inflammatory…”
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A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement by Trombetta, Amelia Chiara, Soldano, Stefano, Contini, Paola, Tomatis, Veronica, Ruaro, Barbara, Paolino, Sabrina, Brizzolara, Renata, Montagna, Paola, Sulli, Alberto, Pizzorni, Carmen, Smith, Vanessa, Cutolo, Maurizio

“…Systemic sclerosis (SSc) is a disorder characterized by immune system alterations, vasculopathy and fibrosis. SSc-related interstitial lung disease (ILD)…”
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CTLA4-Ig treatment induces M1-M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients by Cutolo, Maurizio, Soldano, Stefano, Gotelli, Emanuele, Montagna, Paola, Campitiello, Rosanna, Paolino, Sabrina, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Tardito, Samuele

“…In rheumatoid arthritis (RA), macrophages play an important role in modulating the immunoinflammatory response through their polarisation into "classically"…”
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Influence of Seasonal Vitamin D Changes on Clinical Manifestations of Rheumatoid Arthritis and Systemic Sclerosis by Cutolo, Maurizio, Soldano, Stefano, Sulli, Alberto, Smith, Vanessa, Gotelli, Emanuele

“…Vitamin D [1,25(OH) 2 D—calcitriol] is basically a steroid hormone with pleiotropic biologic effects, and its impact on the regulation of immune system may…”
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Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease by Soldano, Stefano, Smith, Vanessa, Montagna, Paola, Gotelli, Emanuele, Campitiello, Rosanna, Pizzorni, Carmen, Paolino, Sabrina, Sulli, Alberto, Cere, Andrea, Cutolo, Maurizio

“…Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by vasculopathy and progressive fibrosis of skin and several internal organs,…”
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Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity by Cutolo, Maurizio, Gotelli, Emanuele, Montagna, Paola, Tardito, Samuele, Paolino, Sabrina, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Soldano, Stefano

“…Circulating fibrocytes are an important source of fibroblasts and myofibroblasts, which are involved in fibrotic processes, including systemic sclerosis (SSc)…”
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Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease by Soldano, Stefano, Smith, Vanessa, Montagna, Paola, Gotelli, Emanuele, Campitiello, Rosanna, Pizzorni, Carmen, Paolino, Sabrina, Sulli, Alberto, Cere, Andrea, Cutolo, Maurizio

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Alternatively Activated (M2) Macrophage Phenotype Is Inducible by Endothelin-1 in Cultured Human Macrophages by Soldano, Stefano, Pizzorni, Carmen, Paolino, Sabrina, Trombetta, Amelia Chiara, Montagna, Paola, Brizzolara, Renata, Ruaro, Barbara, Sulli, Alberto, Cutolo, Maurizio

“…Alternatively activated (M2) macrophages are phenotypically characterized by the expression of specific markers, mainly macrophage scavenger receptors (CD204…”
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Correction: Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity by Cutolo, Maurizio, Gotelli, Emanuele, Montagna, Paola, Tardito, Samuele, Paolino, Sabrina, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Soldano, Stefano

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Vitamin D and COVID-19: Narrative Review after 3 Years of Pandemic by Gotelli, Emanuele, Soldano, Stefano, Hysa, Elvis, Paolino, Sabrina, Campitiello, Rosanna, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Cutolo, Maurizio

“…Active vitamin D [1,25(OH) D -calcitriol] is a secosteroid hormone whose receptor is expressed on all cells of the immune system. Vitamin D has a global…”
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Correlation between circulating fibrocytes and dermal thickness in limited cutaneous systemic sclerosis patients: a pilot study by Ruaro, Barbara, Soldano, Stefano, Smith, Vanessa, Paolino, Sabrina, Contini, Paola, Montagna, Paola, Pizzorni, Carmen, Casabella, Andrea, Tardito, Samuele, Sulli, Alberto, Cutolo, Maurizio

“…The objective is to detect any possible correlation between the modified Rodnan skin score (mRSS) and dermal thickness (DT) measured by skin high-frequency…”
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Antibodies against specific extractable nuclear antigens (ENAs) as diagnostic and prognostic tools and inducers of a profibrotic phenotype in cultured human skin fibroblasts: are they functional? by Corallo, Claudio, Cheleschi, Sara, Cutolo, Maurizio, Soldano, Stefano, Fioravanti, Antonella, Volpi, Nila, Franci, Daniela, Nuti, Ranuccio, Giordano, Nicola

“…The importance of systemic sclerosis (SSc) autoantibodies for diagnosis has become recognized by their incorporation into the 2013 ACR/EULAR classification…”
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Bosentan and macitentan prevent the endothelial-to-mesenchymal transition (EndoMT) in systemic sclerosis: in vitro study by Corallo, Claudio, Cutolo, Maurizio, Kahaleh, Bashar, Pecetti, Gianluca, Montella, Antonio, Chirico, Chiara, Soldano, Stefano, Nuti, Ranuccio, Giordano, Nicola

“…Systemic sclerosis (SSc) is characterized by early vascular abnormalities and subsequent fibroblast activation to myofibroblasts, leading to fibrosis…”
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Prevalence of hybrid TLR4+M2 monocytes/macrophages in peripheral blood and lung of systemic sclerosis patients with interstitial lung disease by Gotelli, Emanuele, Soldano, Stefano, Feghali-Bostwick, Carol, Montagna, Paola, Campitiello, Rosanna, Contini, Paola, Mora, Marco, Benelli, Roberto, Hysa, Elvis, Paolino, Sabrina, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Cutolo, Maurizio

“…IntroductionSystemic sclerosis (SSc) is a complex autoimmune connective tissue disease characterized by microvascular damage, immune system reactivity and…”
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Vitamin D Immune-Mediated Responses and SARS-CoV-2 Infection: Clinical Implications in COVID-19 by Gotelli, Emanuele, Paolino, Sabrina, Soldano, Stefano, Cutolo, Maurizio

“…Active vitamin D is a true steroid hormone with pleiotropic biological effects that go beyond the classical concept of bone metabolism regulation. In fact,…”
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A Systematic Review of Aminaphtone from Pathophysiology to Clinical Applications: Focus on New Rheumatological Acquisitions by Gotelli, Emanuele, Soldano, Stefano, Hysa, Elvis, Pacini, Greta, Pizzorni, Carmen, Paolino, Sabrina, Cutolo, Maurizio, Sulli, Alberto

“…Aminaphtone is a chemical drug that has been used for more than thirty years to treat a variety of vascular disorders, with good clinical results and a…”
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Effects of selexipag and its active metabolite in contrasting the profibrotic myofibroblast activity in cultured scleroderma skin fibroblasts by Cutolo, Maurizio, Ruaro, Barbara, Montagna, Paola, Brizzolara, Renata, Stratta, Emanuela, Trombetta, Amelia Chiara, Scabini, Stefano, Tavilla, Pier Paolo, Parodi, Aurora, Corallo, Claudio, Giordano, Nicola, Paolino, Sabrina, Pizzorni, Carmen, Sulli, Alberto, Smith, Vanessa, Soldano, Stefano

“…Myofibroblasts contribute to fibrosis through the overproduction of extracellular matrix (ECM) proteins, primarily type I collagen (COL-1) and fibronectin…”
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Effects of CTLA4-Ig treatment on circulating fibrocytes and skin fibroblasts from the same systemic sclerosis patients: an in vitro assay by Cutolo, Maurizio, Soldano, Stefano, Montagna, Paola, Trombetta, Amelia Chiara, Contini, Paola, Ruaro, Barbara, Sulli, Alberto, Scabini, Stefano, Stratta, Emanuela, Paolino, Sabrina, Pizzorni, Carmen, Smith, Vanessa, Brizzolara, Renata

“…Systemic sclerosis (SSc) is characterized by vasculopathy and progressive fibrosis. CTLA4-Ig (abatacept) is able to interact with the cell surface…”
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Use of glucocorticoids and risk of infections by Cutolo, Maurizio, Seriolo, Bruno, Pizzorni, Carmen, Secchi, Maria Elena, Soldano, Stefano, Paolino, Sabrina, Montagna, Paola, Sulli, Alberto

“…Abstract Glucocorticoids (GC) exert many complex quantitative and qualitative immunosuppressive effects that induce cellular immunodeficiency and consequently…”
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