Search Results - "SOGAWA, Kazuhiro"

Attenuation of inhibitory PAS domain protein-induced cell death by synthetic peptides derived from Mcl-1 transmenbrane domain by Kasai, Shuya, Yasumoto, Ken-ichi, Sogawa, Kazuhiro

“…Expression of Inhibitory PAS domain protein (IPAS) induces apoptosis by inhibiting the anti-apoptotic activity of mitochondrial pro-survival proteins including…”
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Chimeric RNA Oligonucleotides Incorporating Triazole-Linked Trinucleotides: Synthesis and Function as mRNA in Cell-Free Translation Reactions by Fujino, Tomoko, Suzuki, Takeru, Okada, Koudai, Kogashi, Kanako, Yasumoto, Ken-ichi, Sogawa, Kazuhiro, Isobe, Hiroyuki

“…A method for the synthesis of chimeric oligonucleotides was developed to incorporate purine nucleobases and multiple triazole linkers in natural,…”
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Direct protein–protein interaction between Npas4 and IPAS mutually inhibits their critical roles in neuronal cell survival and death by Kasai, Shuya, Li, Xianyu, Torii, Satoru, Yasumoto, Ken-ichi, Sogawa, Kazuhiro

“…Inhibitory PAS domain protein (IPAS) is a bifunctional protein that acts as a transcriptional repressor in hypoxia and as a pro-apoptotic protein involved in…”
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Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2 by Kasai, Shuya, Richardson, Mary J. E., Torii, Satoru, Yasumoto, Ken‐ichi, Shima, Hiroki, Igarashi, Kazuhiko, Itoh, Ken, Sogawa, Kazuhiro, Murayama, Kazutaka

“…Inhibitory PAS domain protein (IPAS) is a bifunctional protein that downregulates hypoxic gene expression and exerts proapoptotic activity by preventing…”
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Identification of a novel mechanism of regulation of Ah (dioxin) receptor function by Mimura, J, Ema, M, Sogawa, K, Fujii-Kuriyama, Y

“…Ah receptor (AhR) is a ligand-activated transcription factor that mediates pleiotropic effects of environmental pollutants such as 2,3,…”
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Control of Photobleaching in Photodynamic Therapy Using the Photodecarbonylation Reaction of Ruthenium Phthalocyanine Complexes via Stepwise Two-Photon Excitation by Ishii, Kazuyuki, Shiine, Masahiko, Shimizu, Yoshitaka, Hoshino, Shun-ichi, Abe, Hisaku, Sogawa, Kazuhiro, Kobayashi, Nagao

“…In this study, we have investigated the photochemical properties and photodynamic effects of ruthenium phthalocyanine (RuPc(CO)(Py)) and naphthalocyanine…”
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A Novel bHLH-PAS Factor with Close Sequence Similarity to Hypoxia-Inducible Factor 1α (HIF1α ) Regulates the VEGF, Expression and is Potentially Involved in Lung and Vascular Development by Ema, Masatsugu, Taya, Shinichiro, Yokotani, Noboru, Sogawa, Kazuhiro, Matsuda, Youichi, Fujii-Kuriyama, Yoshiaki

“…We have isolated and characterized a cDNA for a novel Per-Arnt/AhR-Sim basic helix--loop--helix (bHLH-PAS) factor that interacts with the Ah receptor nuclear…”
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Nucleocytoplasmic shuttling of IPAS by its unique nuclear import and export signals unshared with other HIF-3α splice variants by Torii, Satoru, Sakaki, Kohei, Otomo, Miki, Saka, Kyohei, Yasumoto, Ken-ichi, Sogawa, Kazuhiro

“…Inhibitory Per/Arnt/Sim (PAS) domain protein (IPAS) is a splice variant of hypoxia-inducible factor (HIF)-3α, and possesses two entirely different functions…”
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Conformational changes in inhibitory PAS domain protein associated with binding of HIF-1α and Bcl-xL in living cells by Kasai, Shuya, Kajimoto, Shinji, Ito, Yuma, Saito, Tomo, Yasumoto, Ken-Ichi, Tokunaga, Makio, Sakata-Sogawa, Kumiko, Fukumura, Hiroshi, Sogawa, Kazuhiro

“…Inhibitory PAS domain protein (IPAS) is a dual function protein acting as a transcriptional repressor and as a pro-apoptotic protein. Simultaneous dual-color…”
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Tumour necrosis factor-α suppresses the hypoxic response by NF-κB-dependent induction of inhibitory PAS domain protein in PC12 cells by Goryo, Kenji, Torii, Satoru, Yasumoto, Ken-Ichi, Sogawa, Kazuhiro

“…Inflammation is often accompanied by hypoxia. However, crosstalk between signalling pathways activated by inflammation and signalling events that control…”
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Role of the intracellular localization of HIF-prolyl hydroxylases by Yasumoto, Ken-ichi, Kowata, Yusuke, Yoshida, Atsushi, Torii, Satoru, Sogawa, Kazuhiro

“…Hypoxia-inducible factor-1 (HIF-1) is a major transcription factor regulating the response of tumor cells to hypoxia and is comprised of HIF-1α and Arnt…”
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Inhibitory effect of extracellular histidine on cobalt-induced HIF-1α expression by Torii, Satoru, Kurihara, Atsushi, Li, Xian Yu, Yasumoto, Ken-ichi, Sogawa, Kazuhiro

“…Cobalt chloride (CoCl₂) can mimic hypoxia in inducing hypoxia-inducible factor 1 (HIF-1). Several cultured cells were examined for susceptibility to CoCl₂ in…”
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A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor–Arnt heterodimer by Sogawa, Kazuhiro, Numayama-Tsuruta, Keiko, Takahashi, Tomohiro, Matsushita, Natsuki, Miura, Chisa, Nikawa, Jun-ichi, Gotoh, Osamu, Kikuchi, Yasuo, Fujii-Kuriyama, Yoshiaki

“…We have identified an enhancer responsible for induction by 3-methylcholanthrene in the upstream region of the CYP1A2 gene. The enhancer does not contain the…”
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Structure and Expression of the Ah Receptor Repressor Gene by Baba, Takashi, Mimura, Junsei, Gradin, Katarina, Kuroiwa, Asato, Watanabe, Takafumi, Matsuda, Yoichi, Inazawa, Johji, Sogawa, Kazuhiro, Fujii-Kuriyama, Yoshiaki

“…The aryl hydrocarbon receptor (AhR) repressor (AhRR) gene has been isolated and characterized from a mouse genomic library. The gene is distributed as 11 exons…”
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Magnesium Deficiency Causes Loss of Response to Intermittent Hypoxia in Paraganglion Cells by Torii, Satoru, Kobayashi, Kentaro, Takahashi, Masayuki, Katahira, Kasumi, Goryo, Kenji, Matsushita, Natsuki, Yasumoto, Ken-ichi, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…Magnesium deficiency is suggested to contribute to many age-related diseases. Hypoxia-inducible factor 1α (HIF-1α) is known to be a master regulator of hypoxic…”
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Excitation energy migration in yellow fluorescent protein (citrine) layers adsorbed on modified gold surfaces by Yusoff, Hanis Mohd, Rzeźnicka, Izabela I., Hoshi, Hirotaka, Kajimoto, Shinji, Horimoto, Noriko Nishizawa, Sogawa, Kazuhiro, Fukumura, Hiroshi

“…•Citrine (one of yellow fluorescent protein variants) was not denatured by the adsorption and drying on modified gold surfaces.•Fluorescence anisotropy decay…”
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Triazole-Linked DNA as a Primer Surrogate in the Synthesis of First-Strand cDNA by Fujino, Tomoko, Yasumoto, Ken-ichi, Yamazaki, Naomi, Hasome, Ai, Sogawa, Kazuhiro, Isobe, Hiroyuki

“…A phosphate‐eliminated nonnatural oligonucleotide serves as a primer surrogate in reverse transcription reaction of mRNA. Despite of the nonnatural triazole…”
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The Transcriptional Activation Function of the HIF-like Factor Requires Phosphorylation at a Conserved Threonine by Gradin, Katarina, Takasaki, Chikahisa, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…The hypoxia-inducible factor (HIF)-1α and the HIF-like factor (HLF) transcription factors are regulated at multiple levels including protein stabilization,…”
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Loss of teratogenic response to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) in mice lacking the Ah (dioxin) receptor by Mimura, Junsei, Yamashita, Keisuke, Nakamura, Kenji, Morita, Masanobu, Takagi, Toshio N., Nakao, Kazuki, Ema, Masatsugu, Sogawa, Kazuhiro, Yasuda, Mineo, Katsuki, Motoya, Fujii‐Kuriyama, Yoshiaki

“…Background: The aryl hydrocarbon receptor (AhR or dioxin receptor) is a ligand‐activated transcription factor that is considered to mediate pleiotropic…”
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Identification of amino acid residues in the Ah receptor involved in ligand binding by Goryo, Kenji, Suzuki, Ai, Carpio, Carlos A. Del, Siizaki, Kazuhiro, Kuriyama, Eisuke, Mikami, Yoshinori, Kinoshita, Koshi, Yasumoto, Ken-ichi, Rannug, Agneta, Miyamoto, Akira, Fujii-Kuriyama, Yoshiaki, Sogawa, Kazuhiro

“…The Ah receptor (AhR) is a ligand-activated transcription factor. Five amino acids as candidate amino acids necessary for ligand binding within or near the…”
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