Search Results - "SOFIA, Antonella"
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Homocysteine exchange across skeletal muscle in patients with chronic kidney disease
Published in Physiological reports (01-03-2023)“…Sites and mechanisms regulating the supply of homocysteine (Hcy) to the circulation are unexplored in humans. We studied the exchange of Hcy across the forearm…”
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The Organ Handling of Soluble Klotho in Humans
Published in Kidney & blood pressure research (01-08-2019)“…Background: Chronic kidney disease (CKD) reduces both Klotho expression and its shedding into circulation, an effect that accelerates progression and…”
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Effects of Low-Protein, and Supplemented Very Low–Protein Diets, on Muscle Protein Turnover in Patients With CKD
Published in Kidney international reports (01-05-2018)“…Early studies have shown that patients with chronic kidney disease (CKD) are able to maintain nitrogen balance despite significantly lower protein intake, but…”
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Effects of Late Conversion from Twice-Daily to Once-Daily Slow Release Tacrolimus on the Insulin Resistance Indexes in Kidney Transplant Patients
Published in Transplantology (Basel, Switzerland) (03-02-2021)“…The use of tacrolimus (Tac) may be involved in the development of new-onset diabetes after transplantation (NODAT) in a dose-related manner. This study aimed…”
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P0915PROTEIN ENERGY WASTING IS ASSOCIATED WITH A DECLINE IN MUSCLE PROTEIN SYNTHESIS IN CKD PATIENTS
Published in Nephrology, dialysis, transplantation (01-06-2020)“…Abstract Background and Aims Skeletal muscle is a highly adaptive tissue, however even small imbalances between protein synthesis and degradation can lead to…”
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Biochemical profile of renal amyloidosis in a Latin American cohort
Published in Journal of nephrology (03-09-2024)“…Two-thirds of patients with immunoglobulin light chain (AL) amyloidosis have renal involvement. The biochemical profile of kidney damage is poorly described. A…”
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Amino acid and protein metabolism in the human kidney and in patients with chronic kidney disease
Published in Clinical nutrition (Edinburgh, Scotland) (01-08-2010)“…Summary The progressive loss of kidney function in patients with chronic kidney disease (CKD) is associated with a number of complications, including…”
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Toll‐like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease
Published in Journal of cachexia, sarcopenia and muscle (01-02-2017)“…Background Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up‐regulates pro‐inflammatory…”
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Protein-energy wasting and mortality in chronic kidney disease
Published in International journal of environmental research and public health (01-05-2011)“…Protein-energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with an increased death risk from cardiovascular…”
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Apoptosis and myostatin mRNA are upregulated in the skeletal muscle of patients with chronic kidney disease
Published in Kidney international (01-04-2011)“…Apoptosis and myostatin are major mediators of muscle atrophy and might therefore be involved in the wasting of uremia. To examine whether they are expressed…”
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Changing Trends in B-Cell Non-Hodgkin Lymphoma Treatment: The Role of Novel Monoclonal Antibodies in Clinical Practice
Published in Cancers (01-11-2023)“…We are currently witnessing a dramatic shift in our approach to the treatment of B-cell non-Hodgkin lymphoma (B-NHL). In the evolving clinical landscape, novel…”
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SA-β-Gal in Kidney Tubules as a Predictor of Renal Outcome in Patients with Chronic Kidney Disease
Published in Journal of clinical medicine (01-01-2024)“…Cellular senescence has emerged as an important driver of aging and age-related disease in the kidney. The activity of β-galactosidase at pH 6 (SA-β-Gal) is a…”
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Interorgan handling of fibroblast growth factor-23 in humans
Published in American journal of physiology. Renal physiology (01-02-2017)“…Fibroblast growth factor-23 (FGF-23) accumulates in blood of patients with chronic kidney disease (CKD) and is associated both with cardiovascular…”
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SP264THE KIDNEY IS THE MAJOR SITE FOR THE REGULATION OF SOLUBLE KLOTHO IN HUMANS
Published in Nephrology, dialysis, transplantation (01-05-2017)Get full text
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Effects of Chronic Metabolic Acidosis on Splanchnic Protein Turnover and Oxygen Consumption in Human Beings
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2010)“…Background & Aims Although metabolic acidosis stimulates protein catabolism, its effects on splanchnic protein turnover and energy expenditure have not been…”
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Effects of uremia and inflammation on growth hormone resistance in patients with chronic kidney diseases
Published in Kidney international (01-10-2008)“…Resistance to the anabolic action of growth hormone may contribute to the loss of strength and muscle mass in adult patients with chronic kidney disease. We…”
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Prevalence and Clinical Correlates of Microalbuminuria in Essential Hypertension: The MAGIC Study
Published in Hypertension (Dallas, Tex. 1979) (01-11-1997)“…The prevalence of microalbuminuria and its relationship with several cardiovascular risk factors and target organ damage were evaluated in a cohort of 787…”
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Mechanisms of renal ammonia production and protein turnover
Published in Metabolic brain disease (01-03-2009)“…Renal synthesis and excretion of ammonia are critical for efficient removal of acids from the body. Besides the rate of ammonia production, the intrarenal…”
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Kidney and splanchnic handling of Interleukin-6 in humans
Published in Cytokine (Philadelphia, Pa.) (2007)“…Chronic elevation of circulating Interleukin-6 (IL-6) is observed in elderly individuals as well as in several illnesses, including chronic kidney diseases. A…”
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