Search Results - "SOENO, CHIE"
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Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer
Published in Molecular cancer therapeutics (01-11-2015)“…Patients with non-small cell lung cancer (NSCLC) EGFR mutations have shown a dramatic response to EGFR inhibitors (EGFR-TKI). EGFR T790M mutation and MET…”
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miR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma
Published in Oncology reports (01-12-2014)“…Malignant pleural mesothelioma (MPM) is a rapidly fatal malignancy that is increasing in incidence in Japan. In this study, we performed gene and microRNA…”
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Histone deacetylase inhibitor enhances sensitivity of non‐small‐cell lung cancer cells to 5‐FU/S‐1 via down‐regulation of thymidylate synthase expression and up‐regulation of p21waf1/cip1 expression
Published in Cancer science (01-06-2010)“…It is desirable to find more appropriate therapeutic opportunities in non‐small‐cell lung cancer (NSCLC) due to the current poor prognosis of affected…”
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Significance of osteopontin in the sensitivity of malignant pleural mesothelioma to pemetrexed
Published in International journal of oncology (01-06-2014)“…Pemetrexed (PEM) is currently recommended as one of the standard anticancer drugs for malignant pleural mesothelioma (MPM). However, the mechanism of the…”
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Journal Article -
5
Histone deacetylase inhibitor enhances sensitivity of non‐small‐cell lung cancer cells to 5‐FU/S‐1 via down‐regulation of thymidylate synthase expression and up‐regulation of p21 waf1/cip1 expression
Published in Cancer science (10-06-2010)“…It is desirable to find more appropriate therapeutic opportunities in non‐small‐cell lung cancer (NSCLC) due to the current poor prognosis of affected…”
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MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells
Published in International journal of oncology (01-09-2012)“…Transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition (EMT) has been shown to be related to the pathogenesis of various diseases…”
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miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells
Published in International journal of oncology (01-03-2016)“…Nintedanib (BIBF1120) is a multi-targeted angiokinase inhibitor and has been evaluated in idiopathic pulmonary fibrosis and advanced non-small cell lung cancer…”
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Identification of haptoglobin peptide as a novel serum biomarker for lung squamous cell carcinoma by serum proteome and peptidome profiling
Published in International journal of oncology (01-03-2016)“…To date, a number of potential biomarkers for lung squamous cell cancer (SCC) have been identified; however, sensitive biomarkers are currently lacking to…”
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MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation
Published in BMC cancer (06-02-2015)“…Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib. However, drug resistance eventually emerges which limits the…”
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Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer
Published in BMC cancer (09-04-2015)“…Mammalian target of rapamycin (mTOR) inhibitors have anti-tumor effects against renal cell carcinoma, pancreatic neuroendocrine cancer and breast cancer. In…”
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(2)The Anticancer Effect of Histone Deacetylase Inhibitors and Combination with the Cytotoxic Agents in Lung Cancer Cells: Biological Analyses for Future Clinical Application
Published in Journal of Nippon Medical School (2009)“…「Introduction」 Even though a wide range of anticancer agents have been developed, many patients with advanced solid tumors still have a poor prognosis. For the…”
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Abstract 756: Inhibition of ABCB1 overcomes cancer stem cell-like properties and acquired resistance to MET inhibitor in non-small cell lung cancer
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Non-small cell lung cancer (NSCLC) patients with EGFR mutations have shown a dramatic response to EGFR inhibitors (EGFR-TKI). EGFR T790M mutation and MET…”
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Abstract 3541: Significance of osteopontin in the sensitivity of malignant pleural mesothelioma cells to pemetrexed
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Introduction: Malignant pleural mesothelioma (MPM) is one of the fatal cancers associated with asbestos exposure.Pemetrexed (PEM) is currently recommended as…”
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Abstract 784: Significance of osteopontin in the sensitivity of malignant pleural mesothelioma to pemetrexed
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Background: Pemetrexed (PEM) is currently recommended as one of the standard anticancer drugs for malignant pleural mesothelioma (MPM). However, the mechanism…”
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Abstract 2298: MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in pulmonary epithelium cells
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition (EMT) has been reported to be related to pathogenesis of various diseases…”
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Journal Article -
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Abstract 5548: High copy number of the MET gene predicts resistance to EGFR-TKI in non-small cell lung cancer patients
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Background Non-small cell lung cancer (NSCLC) patients with EGFR gene mutations have shown a dramatic responses to EGFR tyrosine kinase inhibitor (EGFR-TKI)…”
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HSP27 modulates epithelial to mesenchymal transition of lung cancer cells in a Smad-independent manner
Published in Oncology letters (01-11-2010)“…Epithelial to mesenchymal transition (EMT) is induced by transforming growth factor-β1 (TGF-β1) and is a crucial event for cancer cells to acquire invasive and…”
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Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression
Published in Cancer science (01-06-2010)“…It is desirable to find more appropriate therapeutic opportunities in non-small-cell lung cancer (NSCLC) due to the current poor prognosis of affected…”
Get full text
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