Search Results - "SOELDNER, J. S"

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study by Martin, B C, Warram, J H, Krolewski, A S, Bergman, R N, Soeldner, J S, Kahn, C R

“…Type 2 diabetes mellitus is characterised by resistance of peripheral tissues to insulin and a relative deficiency of insulin secretion. To find out which is…”
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Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents by Warram, J H, Martin, B C, Krolewski, A S, Soeldner, J S, Kahn, C R

“…To determine whether insulin resistance or insulin deficiency is primary in the pathogenesis of type II diabetes. Cohort analytic study of persons with normal…”
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Acute postchallenge hyperinsulinemia predicts weight gain: a prospective study by Sigal, R. J., El-Hashimy, M., Martin, B. C., Soeldner, J. S., Krolewski, A. S., Warram, J. H.

“…Acute postchallenge hyperinsulinemia predicts weight gain: a prospective study. R J Sigal , M El-Hashimy , B C Martin , J S Soeldner , A S Krolewski and J H…”
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Late progression to diabetes and evidence for chronic beta-cell autoimmunity in identical twins of patients with type I diabetes by Verge, C. F., Gianani, R., Yu, L., Pietropaolo, M., Smith, T., Jackson, R. A., Soeldner, J. S., Eisenbarth, G. S.

“…Late progression to diabetes and evidence for chronic beta-cell autoimmunity in identical twins of patients with type I diabetes. C F Verge , R Gianani , L Yu…”
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Familial clustering of insulin sensitivity by Martin, B. C., Warram, J. H., Rosner, B., Rich, S. S., Soeldner, J. S., Krolewski, A. S.

“…Familial clustering of insulin sensitivity. B C Martin , J H Warram , B Rosner , S S Rich , J S Soeldner and A S Krolewski Section on Epidemiology and…”
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Prognostically significant heterogeneity of cytoplasmic islet cell antibodies in relatives of patients with type I diabetes by Gianani, R., Pugliese, A., Bonner-Weir, S., Shiffrin, A. J., Soeldner, J. S., Erlich, H., Awdeh, Z., Alper, C. A., Jackson, R. A., Eisenbarth, G. S.

“…Prognostically significant heterogeneity of cytoplasmic islet cell antibodies in relatives of patients with type I diabetes. R Gianani , A Pugliese , S…”
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Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes by BAEKKESKOV, S, LANDIN, M, SUNDQUIST, G, LERNMARK, A, KRISTENSEN, J. K, SRIKANTA, S, BRUINING, G. J, MANDRUP-POULSEN, T, DE BEAUFORT, C, SOELDNER, J. S, EISENBARTH, G, LINDGREN, F

“…Antibodies in sera from newly diagnosed insulin-dependent diabetes mellitus (IDDM) patients are directed to a human islet cell protein of relative molecular…”
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Pre-type I diabetes. Linear loss of beta cell response to intravenous glucose by SRIKANTA, S, GANDA, O. P, GLEASON, R. E, JACKSON, R. A, SOELDNER, J. S, EISENBARTH, G. S

“…Pre-type I diabetes. Linear loss of beta cell response to intravenous glucose. S Srikanta , O P Ganda , R E Gleason , R A Jackson , J S Soeldner and G S…”
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Competitive insulin autoantibody assay: prospective evaluation of subjects at high risk for development of type I diabetes mellitus by VARDI, P, TUTTLEMAN, M, CONNELLY, J. E, GRINBERGS, M, RADIZABETH, A, RILEY, W. J, MACLAREN, N. K, EISENBARTH, G. S, SOELDNER, J. S

“…A quantitative fluid-phase radioassay for autoantibodies reacting with insulin (competitive insulin autoantibody assay, CIAA) was developed. The assay's…”
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Life-table analysis of progression to diabetes of anti-insulin autoantibody-positive relatives of individuals with type I diabetes by Ziegler, A. G., Ziegler, R., Vardi, P., Jackson, R. A., Soeldner, J. S., Eisenbarth, G. S.

“…Life-table analysis of progression to diabetes of anti-insulin autoantibody-positive relatives of individuals with type I diabetes. A G Ziegler , R Ziegler , P…”
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Genetically programmed selective islet beta-cell loss in diabetic subjects with Wolfram's syndrome by Karasik, A, O'Hara, C, Srikanta, S, Swift, M, Soeldner, J S, Kahn, C R, Herskowitz, R D

“…Genetically programmed selective islet beta-cell loss in diabetic subjects with Wolfram's syndrome. A Karasik , C O'Hara , S Srikanta , M Swift , J S Soeldner…”
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Natural history of impaired glucose tolerance: follow-up at Joslin Clinic by Warram, J H, Sigal, R J, Martin, B C, Krolewski, A S, Soeldner, J S

“…The goal of this study was to examine follow-up data on the offspring of two parents with NIDDM who have IGT to identify predictors of progression to NIDDM…”
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Autoimmunity to insulin, beta cell dysfunction, and development of insulin-dependent diabetes mellitus by SRIKANTA, S, RICKER, A. T, MCCULLOCH, D. K, SOELDNER, J. S, EISENBARTH, G. S, PALMER, J. P

“…Circulating insulin autoantibodies (INSAAb) were measured in discordant monozygotic twins, first-degree relatives, and other groups at "high risk" for the…”
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Clinical consequences of acquired transfusional iron overload in adults by Schafer, A I, Cheron, R G, Dluhy, R, Cooper, B, Gleason, R E, Soeldner, J S, Bunn, H F

“…We assessed the clinical sequelae of transfusional iron overload in 15 nonthalassemic adults (40 to 71 years of age) with anemias requiring transfusions. Iron…”
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Acute postchallenge hyperinsulinemia predicts weight gain: A prospective study by SIGAL, R. J, EL-HASHIMY, M, MARTIN, B. C, SOELDNER, J. S, KROLEWSKI, A. S, WARRAM, J. H

“…The relationships of insulin secretion and insulin action to body weight are incompletely understood. Obesity is associated with reduced sensitivity to insulin…”
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Type I diabetes mellitus in monozygotic twins: chronic progressive beta cell dysfunction by Srikanta, S, Ganda, O P, Jackson, R A, Gleason, R E, Kaldany, A, Garovoy, M R, Milford, E L, Carpenter, C B, Soeldner, J S, Eisenbarth, G S

“…In a prospective 21-year study, islet cell antibodies and beta cell function were serially assessed in 24 monozygotic twins initially discordant for type I…”
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Insulin Resistance Is a Poor Predictor of Type 2 Diabetes in Individuals with No Family History of Disease by Goldfine, Allison B., Bouche, Clara, Parker, Robert A., Kim, Caroline, Kerivan, Amy, Soeldner, J. Stuart, Martin, Blaise C., Warram, James H., Kahn, C. Ronald

“…In normoglycemic offspring of two type 2 diabetic parents, low insulin sensitivity (SI) and low insulin-independent glucose effectiveness (SG) predict the…”
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Specific association of HLA-DR4 with increased prevalence and level of insulin autoantibodies in first-degree relatives of patients with type I diabetes by Ziegler, R., Alper, C. A., Awdeh, Z. L., Castano, L., Brink, S. J., Soeldner, J. S., Jackson, R. A., Eisenbarth, G. S.

“…Specific association of HLA-DR4 with increased prevalence and level of insulin autoantibodies in first-degree relatives of patients with type I diabetes. R…”
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Autoimmunity to insulin, beta cell dysfunction, and development of insulin-dependent diabetes mellitus by Srikanta, S., Ricker, A. T., McCulloch, D. K., Soeldner, J. S., Eisenbarth, G. S., Palmer, J. P.

“…Autoimmunity to insulin, beta cell dysfunction, and development of insulin-dependent diabetes mellitus. S Srikanta , A T Ricker , D K McCulloch , J S Soeldner…”
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Differential sensitivity to β-cell secretagogues in early, type I diabetes mellitus by GANDA, O. P, SRIKANTA, S, BRINK, S. J, MORRIS, M. A, GLEASON, R. E, SOELDNER, J. S, EISENBARTH, G. S

“…The insulin secretory response to various beta-cell secretagogues was studied in four children (ages 11, 11, 12, and 10 yr) in "early" stages or remission of…”
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