Search Results - "SODUM, R. S"

1,N2-Ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal by SODUM, R. S, FUNG-LUNG CHUNG

“…The reaction of trans-4-hydroxy-2-nonenal, a major alpha, beta-unsaturated aldehyde released during lipid peroxidation, with deoxyguanosine under physiological…”
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Inhibition of 2-nitropropane-induced rat liver DNA and RNA damage by benzyl selenocyanate by FIALA, E. S, OCK SOON SOHN, LI, H, EL-BAYOUMY, K, SODUM, R. S

“…We observed that pretreatment of male F344 rats with benzyl selenocyanate, a versatile organoselenium chemopreventive agent in several animal model systems,…”
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8-Aminoguanine: A base modification produced in rat liver nucleic acids by the hepatocarcinogen 2-nitropropane by Sodum, Rama S, Nie, Guo, Fiala, Emerich S

“…2-Nitropropane (2-NP), an important industrial chemical and a hepatocarcinogen in rats, had previously been found to produce several modifications of…”
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Secondary nitroalkanes: Induction of DNA repair in rat hepatocytes, activation by aryl sulfotransferase and hepatocarcinogenicity of 2-nitrobutane and 3-nitropentane in male F344 rats by Fiala, Emerich S., Sodum, Rama S., Hussain, Nalband S., Rivenson, Abraham, Dolan, Lisa

“…The secondary nitroalkanes, 2-nitropropane, 2-nitrobutane, 3-nitropentane, 2-nitroheptane, nitrocyclopentane and nitrocyclohexane, as well as the primary…”
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Activation of the Liver Carcinogen 2-Nitropropane by Aryl Sulfotransferase by Sodum, Rama S, Sohn, Ock Soon, Nie, Guo, Fiala, Emerich S

“…8-Aminoguanine had previously been identified as one of the nucleic acid base modifications produced in livers of rats by treatment with the hepatocarcinogen…”
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Analysis of Peroxynitrite Reactions with Guanine, Xanthine, and Adenine Nucleosides by High-Pressure Liquid Chromatography with Electrochemical Detection:  C8-Nitration and -Oxidation by Sodum, Rama S, Fiala, Emerich S

“…Peroxynitrite, the reaction product of nitric oxide and superoxide anion, and a powerful oxidant, was found to nitrate as well as oxidize adenine, guanine, and…”
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Determination of 3-Nitrotyrosine by High-Pressure Liquid Chromatography with a Dual-Mode Electrochemical Detector by Sodum, Rama S., Akerkar, Shobha A., Fiala, Emerich S.

“…3-Nitrotyrosine, a product of tyrosine nitration, is useful as a marker for the generation of reactive nitrogen oxide species with short half-lives such as…”
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Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal by SODUM, R. S, FUNG-LUNG CHUNG

“…This paper describes the reactions of purine nucleosides and nucleic acids with 2,3-epoxy-4-hydroxynonanal. 2,3-Epoxy-4-hydroxynonanal was produced with…”
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(-)-Epigallocatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitrite-mediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine by Fiala, E S, Sodum, R S, Bhattacharya, M, Li, H

“…Reaction with peroxynitrite at pH 7.4 and 37 degrees C was found to increase the 8-oxodeoxyguanosine levels in calf thymus DNA 35- 38-fold. This oxidation of…”
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N2-Amination of Guanine to 2-Hydrazinohypoxanthine, a Novel in Vivo Nucleic Acid Modification Produced by the Hepatocarcinogen 2-Nitropropane by Sodum, Rama S, Fiala, Emerich S

“…2-Nitropropane, an industrial chemical and a hepatocarcinogen in rats, induces aryl sulfotransferase-mediated liver DNA and RNA base modifications [Sodum, R…”
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Structural characterization of adducts formed in the reaction of 2,3-epoxy-4-hydroxynonanal with deoxyguanosine by Sodum, Rama S, Chung, Fung Lung

“…Six adducts were isolated by reverse-phase high-performance liquid chromatography from the reaction of deoxyguanosine at 50 degrees C in pH 7.0 buffer with the…”
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(−)-Epigallocatechin gallate, a polyphenolic tea antioxidant, inhibits peroxynitritemediated formation of 8-oxodeoxyguanosine and 3-nitrotyrosine by Fiala, E. S., Sodum, R. S., Bhattacharya, M., Li, H.

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Reactions of nucleosides with glyoxal and acrolein by Shapiro, R, Sodum, R S, Everett, D W, Kundu, S K

“…The structural determination of the products formed by the reaction of derivatives of glyoxal with guanine are reviewed, as are the applications of these…”
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N super(2)-amination of guanine to 2-hydrazinohypoxanthine, a novel in vivo nucleic acid modification produced by the hepatocarcinogen 2-nitropropane by Sodum, R S, Fiala, E S

“…2-Nitropropane, an industrial chemical and a hepatocarcinogen in rats, induces aryl sulfotransferase-mediated liver DNA and RNA base modifications [Sodum, R…”
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The chemistry of 4-pyrimidinones: Acetylation and ring-opening reactions by Sodum, Rama S., Klein, Robert S., Otter, Brian A.

“…4(3H)‐Pyrimidinone, as well as its 5‐acetoxy and 5‐methoxy derivatives, undergoes selective acetylation at N‐1 when treated with acetic anhydride. In the…”
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Amination of Tyrosine in Liver Cytosol Protein of Male F344 Rats Treated with 2-Nitropropane, 2-Nitrobutane, 3-Nitropentane, or Acetoxime by Sodum, Rama S, Fiala, Emerich S

“…Previously, the secondary nitroalkane 2-nitropropane, a strong hepatocarcinogen in rats, had been shown to induce the formation of 8-aminoguanine in both DNA…”
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Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E by Fiala, Emerich S., Sohn, Ock Soon, Wang, Chung-Xiou, Seibert, Eleanore, Tsurutani, Junji, Dennis, Phillip A., El-Bayoumy, Karam, Sodum, Rama S., Desai, Dhimant, Reinhardt, Joel, Aliaga, Cesar

“…The development of effective chemopreventive agents against cigarette smoke-induced lung cancer could be greatly facilitated by the availability of suitable…”
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1,N super(2)-ethenodeoxyguanosine as a potential marker for DNA adduct formation by trans-4-hydroxy-2-nonenal by Sodum, R S, Chung, Fung-Lung

“…The reaction of trans-4-hydroxy-2-nonenal, a major alpha , beta -unsaturated aldehyde released during lipid peroxidation, with deoxyguanosine under…”
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