Search Results - "SODER, Olle"

Testicular organoid generation by a novel in vitro three-layer gradient system by Alves-Lopes, João Pedro, Söder, Olle, Stukenborg, Jan-Bernd

“…Abstract A system that models the testicular microenvironment and spermatogonial stem-cell (SSC) niche in vitro has not been produced yet. Here, we developed…”
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Child Health Systems in Sweden by Wettergren, Björn, MD, Blennow, Margareta, MD, Hjern, Anders, MD, Söder, Olle, MD, Ludvigsson, Jonas F., MD

“…On a national level, several factors are responsible for Sweden's leading position in achieving the excellent health of children because Sweden has experienced…”
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Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties by Baert, Yoni, De Kock, Joery, Alves-Lopes, João P., Söder, Olle, Stukenborg, Jan-Bernd, Goossens, Ellen

“…So far, successful de novo formation of testicular tissue followed by complete spermatogenesis in vitro has been achieved only in rodents. Our findings reveal…”
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Impact of uteroplacental insufficiency on ovarian follicular pool in the rat by Pampanini, Valentina, Jahnukainen, Kirsi, Sahlin, Lena, Germani, Daniela, Puglianiello, Antonella, Cianfarani, Stefano, Söder, Olle

“…A low oxygen supply to the fetus causes intrauterine growth restriction and can affect gonadal development of the offspring, having a potential impact on…”
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Epididymal expression of the forkhead transcription factor Foxi1 is required for male fertility by Blomqvist, Sandra Rodrigo, Vidarsson, Hilmar, Söder, Olle, Enerbäck, Sven

“…An essential aspect of male reproductive capacity is the immediate availability of fertilization‐ready spermatozoa. To ensure this, most mammals rely on…”
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Hypogonadotrophic hypogonadism, delayed puberty and risk for neurodevelopmental disorders by Ohlsson Gotby, Vide, Söder, Olle, Frisén, Louise, Serlachius, Eva, Bölte, Sven, Almqvist, Catarina, Larsson, Henrik, Lichtenstein, Paul, Tammimies, Kristiina

“…Hypogonadotrophic hypogonadism (HH) is a rare disorder that manifests absent puberty and infertility. Genetic syndromes with hypogonadism, such as Klinefelter…”
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Male germ cell development in humans by Stukenborg, Jan-Bernd, Kjartansdóttir, Kristín Rós, Reda, Ahmed, Colon, Eugenia, Albersmeier, Jan Philipp, Söder, Olle

“…Germ cells are unique cells that possess the ability to transmit genetic information between generations. Detailed knowledge about the molecular and cellular…”
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Later puberty onset among chronically undernourished adolescents living in a Karachi slum, Pakistan by Campisi, Susan C., Humayun, Khadija N., Rizvi, Arjumand, Lou, Wendy, Söder, Olle, Bhutta, Zulfiqar A.

“…Aim To assess factors associated with the timing of puberty onset (Tanner Stage Breast 2/Genital 2) among adolescents living in an urban slum in Karachi,…”
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The Exposure of Fetuses and Children to Endocrine Disrupting Chemicals: A European Society for Paediatric Endocrinology (ESPE) and Pediatric Endocrine Society (PES) Call to Action Statement by Skakkebaek, Niels E, Toppari, Jorma, Söder, Olle, Gordon, Catherine M, Divall, Sara, Draznin, Martin

“…Objective: During recent years, evidence has accumulated that both wildlife species and humans are exposed to ubiquitous endocrine-disrupting chemicals. Some…”
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Medium- and time-related effects on hypothermic storage of rat testicular cells by Elfageih, Rageia, Reda, Ahmed, Kjartansdottir, Kristin Ros, Pampanini, Valentina, Soder, Olle, Stukenborg, Jan-Bernd

“…Testicular samples obtained for fertility preservation often need to be transported between clinics. This study aimed to mimic this short-term hypothermic…”
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Doxorubicin induces apoptosis in germ line stem cells in the immature rat testis and amifostine cannot protect against this cytotoxicity by MI HOU, CHRYSIS, Dionisios, NURMIO, Mirja, PARVINEN, Martti, EKSBORG, Staffan, SÖDER, Olle, JAHNUKAINEN, Kirsi

“…The underlying primary damage to the seminiferous epithelium caused by chemotherapeutic regimens at childhood is largely unknown. The present investigation was…”
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Similar causes of various reproductive disorders in early life by Svechnikov, Konstantin, Stukenborg, Jan-Bernd, Savchuck, Iuliia, Söder, Olle

“…During the past few decades, scientific evidence has been accumulated concerning the possible adverse effects of the exposure to environmental chemicals on the…”
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Bortezomib treatment causes long-term testicular dysfunction in young male mice by Hou, Mi, Eriksson, Emma, Svechnikov, Konstantin, Jahnukainen, Kirsi, Söder, Olle, Meinhardt, Andreas, Sävendahl, Lars

“…With increased long-term survivors of childhood cancer patients, therapy-associated infertility has become one of the most common late side-effects and…”
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Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice by Shabalina, Irina G., Landreh, Luise, Edgar, Daniel, Hou, Mi, Gibanova, Natalia, Atanassova, Nina, Petrovic, Natasa, Hultenby, Kjell, Söder, Olle, Nedergaard, Jan, Svechnikov, Konstantin

“…Point mutations and deletions of mitochondrial DNA (mtDNA) accumulate in tissues during aging in animals and humans and are the basis for mitochondrial…”
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Telomere length regulators are activated in young men after pediatric kidney transplantation compared to healthy controls and survivors of childhood cancer—A cross‐sectional study by Endén, Kira, Tainio, Juuso, Hou, Mi, Suominen, Anu, Pakarinen, Mikko, Huang, Tao, Söder, Olle, Jalanko, Hannu, Jahnukainen, Kirsi, Jahnukainen, Timo

“…Chronic diseases are known to cause premature aging and frailty. Data about telomere length and telomere length‐regulating proteins after pediatric KTx are…”
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Effects of resveratrol analogs on steroidogenesis and mitochondrial function in rat Leydig cells in vitro by Svechnikov, Konstantin, Spatafora, Carmela, Svechnikova, Irina, Tringali, Corrado, Söder, Olle

“…Resveratrol and its analogs are considered to be a promising drug candidate for treatment of cancer and different age‐associated diseases. In the present study…”
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Phthalates Exert Multiple Effects on Leydig Cell Steroidogenesis by Svechnikov, Konstantin, Savchuk, Iuliia, Morvan, Marie-Line, Antignac, Jean-Philippe, Le Bizec, Bruno, Söder, Olle

“…Humans are significantly exposed to phthalates via food packaging, cosmetics and medical devices such as tubings and catheters. Testicular Leydig cells (LCs)…”
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Growth charts and long-term sequelae in extreme preterm infants - from full-term age to 10 years by Horemuzova, Eva, Åmark, Per, Jacobson, Lena, Söder, Olle, Hagenäs, Lars

“…Aim To describe growth pattern from full‐term age to 10 years in infants born before 26 weeks of gestation. Method This retrospective longitudinal cohort…”
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Decontamination of leukemic cells and enrichment of germ cells from testicular samples from rats with Roser’s T-cell leukemia by flow cytometric sorting by Hou, Mi, Andersson, Margareta, Zheng, Chengyun, Sundblad, Anne, Söder, Olle, Jahnukainen, Kirsi

“…Testicular germ cell transplantation is a novel strategy for preservation of fertility in prepubertal cancer patients, but the risk of reseeding tumor cells…”
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Insulin solubility transitions by pH‐dependent interactions with proinsulin C‐peptide by Landreh, Michael, Alvelius, Gunvor, Willander, Hanna, Stukenborg, Jan‐Bernd, Söder, Olle, Johansson, Jan, Jörnvall, Hans

“…Proinsulin processing into insulin and C‐peptide in the secretory granules of the pancreatic β‐cells occurs under mildly acidic conditions and at high peptide…”
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