Search Results - "SOBHANI, Iradj"
-
1
DNA Methylation Is a Main Key for Bacteria-Related Colon Carcinogenesis
Published in Microorganisms (Basel) (13-12-2021)“…Colorectal cancer (CRC) is the second most common cause of cancer deaths in men and women combined [...]…”
Get full text
Journal Article -
2
Extensive transmission of microbes along the gastrointestinal tract
Published in eLife (12-02-2019)“…The gastrointestinal tract is abundantly colonized by microbes, yet the translocation of oral species to the intestine is considered a rare aberrant event, and…”
Get full text
Journal Article -
3
Colorectal cancer-associated microbiota contributes to oncogenic epigenetic signatures
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2019)“…Sporadic colorectal cancer (CRC) is a result of complex interactions between the host and its environment. Environmental stressors act by causing host cell DNA…”
Get full text
Journal Article -
4
Characterization of biliary microbiota dysbiosis in extrahepatic cholangiocarcinoma
Published in PloS one (09-03-2021)“…Extrahepatic cholangiocarcinoma (CCA) accounts for 3% of digestive cancers. The role of biliary microbiota as an environment-related modulator has been…”
Get full text
Journal Article -
5
Potential of fecal microbiota for early‐stage detection of colorectal cancer
Published in Molecular systems biology (01-11-2014)“…Several bacterial species have been implicated in the development of colorectal carcinoma (CRC), but CRC‐associated changes of fecal microbiota and their…”
Get full text
Journal Article -
6
Microbial dysbiosis in colorectal cancer (CRC) patients
Published in PloS one (27-01-2011)“…The composition of the human intestinal microbiota is linked to health status. The aim was to analyze the microbiota of normal and colon cancer patients in…”
Get full text
Journal Article -
7
Crypt- and Mucosa-Associated Core Microbiotas in Humans and Their Alteration in Colon Cancer Patients
Published in mBio (16-07-2019)“…We have previously identified a crypt-specific core microbiota (CSCM) in the colons of healthy laboratory mice and related wild rodents. Here, we confirm that…”
Get full text
Journal Article -
8
Bacteria-related changes in host DNA methylation and the risk for CRC
Published in Gut microbes (09-11-2020)“…Colorectal cancer (CRC) is the second most common cause of cancer deaths in men and women combined. Colon-tumor growth is multistage and the result of the…”
Get full text
Journal Article -
9
Contribution of pks+ Escherichia coli ( E . coli ) to Colon Carcinogenesis
Published in Microorganisms (Basel) (30-05-2024)“…Colorectal cancer (CRC) stands as a significant global health concern, ranking second in mortality and third in frequency among cancers worldwide. While only a…”
Get full text
Journal Article -
10
A Study of Hypermethylated Circulating Tumor DNA as a Universal Colorectal Cancer Biomarker
Published in Clinical chemistry (Baltimore, Md.) (01-08-2016)“…Circulating tumor DNA (ctDNA) has emerged as a good candidate for tracking tumor dynamics in different cancer types, potentially avoiding repeated tumor…”
Get full text
Journal Article -
11
Loss of symbiotic and increase of virulent bacteria through microbial networks in Lynch syndrome colon carcinogenesis
Published in Frontiers in oncology (05-02-2024)“…Through a pilot study, we performed whole gut metagenomic analysis in 17 Lynch syndrome (LS) families, including colorectal cancer (CRC) patients and their…”
Get full text
Journal Article -
12
Detection of Streptococcus gallolyticus and Four Other CRC-Associated Bacteria in Patient Stools Reveals a Potential "Driver" Role for Enterotoxigenic Bacteroides fragilis
Published in Frontiers in cellular and infection microbiology (11-03-2022)“…subspecies ( ) is an opportunistic pathogen causing invasive infections in the elderly often associated with colon neoplasia. The prevalence of in the stools…”
Get full text
Journal Article -
13
Extended right colectomy, left colectomy, or segmental left colectomy for splenic flexure carcinomas: a European multicenter propensity score matching analysis
Published in Surgical endoscopy (01-02-2021)“…Background The surgical resection of the splenic flexure carcinoma (SFC) is challenging and the optimal surgical procedure for SFCs remains a matter of debate…”
Get full text
Journal Article -
14
Role of the intestinal microbiome in colorectal cancer surgery outcomes
Published in World journal of surgical oncology (02-12-2019)“…Growing evidence supports the role of the intestinal microbiome in the carcinogenesis of colorectal cancers, but its impact on colorectal cancer surgery…”
Get full text
Journal Article -
15
Functional digestive symptoms and quality of life in patients with Ehlers-Danlos syndromes: results of a national cohort study on 134 patients
Published in PloS one (22-11-2013)“…Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders. Gastrointestinal manifestations in EDS have been described…”
Get full text
Journal Article -
16
Virulent Bacteria as Inflammatory and Immune Co-Factor in Colon Carcinogenesis: Evidence From Two Monozygotic Patients and Validation in CRC Patient and Healthy Cohorts
Published in Frontiers in cellular and infection microbiology (04-11-2021)“…Colorectal carcinoma (CRC) is a common disease, the incidence of which is increasing according to Western lifestyle; it remains to have a poor prognosis…”
Get full text
Journal Article -
17
Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes
Published in Gut microbes (18-12-2023)“…Recently, an intestinal dysbiotic microbiota with enrichment in oral cavity bacteria has been described in colorectal cancer (CRC) patients. Here, we…”
Get full text
Journal Article -
18
The Limits and Avoidance of Biases in Metagenomic Analyses of Human Fecal Microbiota
Published in Microorganisms (Basel) (09-12-2020)“…An increasing body of evidence highlights the role of fecal microbiota in various human diseases. However, more than two-thirds of fecal bacteria cannot be…”
Get full text
Journal Article -
19
The detection of the methylated Wif-1 gene is more accurate than a fecal occult blood test for colorectal cancer screening
Published in PloS one (15-07-2014)“…The clinical benefit of guaiac fecal occult blood tests (FOBT) is now well established for colorectal cancer screening. Growing evidence has demonstrated that…”
Get full text
Journal Article -
20
Intravoxel incoherent motion (IVIM) MR imaging of colorectal liver metastases: Are we only looking at tumor necrosis?
Published in Journal of magnetic resonance imaging (01-02-2014)“…Purpose To determine if intra‐voxel incoherent motion diffusion‐weighted imaging (IVIM‐DWI) parameters, including free molecular‐based (D) and…”
Get full text
Journal Article