Search Results - "SOARES, Fernando A"
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The fusion of two worlds: Non-coding RNAs and extracellular vesicles - diagnostic and therapeutic implications (Review)
Published in International journal of oncology (01-01-2015)“…The role of the extracellular non-coding RNAs, particularly microRNAs present in tumor-derived extravesicles, has been intensively exploited in human cancer as…”
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Prognostic Implications of Altered Human Epidermal Growth Factor Receptors (HERs) in Gastric Carcinomas: HER2 and HER3 Are Predictors of Poor Outcome
Published in Journal of clinical oncology (01-08-2011)“…The human epidermal growth factor receptor (HER) family consists of four members: ErbB-1 (HER1), ErbB-2 (HER2), ErbB-3 (HER3), and ErbB-4 (HER4). These…”
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Tumor microenvironment composition in pediatric classical Hodgkin lymphoma is modulated by age and Epstein-Barr virus infection
Published in International journal of cancer (01-09-2012)“…Classical Hodgkin lymphoma (cHL) is characterized by a small number of neoplastic cells in a background of reactive cells. Children and adults differ in…”
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In situ T regulatory cells and Th17 cytokines in paired samples of leprosy type 1 and type 2 reactions
Published in PloS one (08-06-2018)“…Leprosy is a complex chronic, infectious dermato-neurological disease that affects the skin and peripheral nerves especially during immuno-inflammatory…”
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GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker
Published in Clinics (São Paulo, Brazil) (01-01-2011)“…To analyze glucose transporter 1 expression patterns in malignant tumors of various cell types and evaluate their diagnostic value by immunohistochemistry…”
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Prevalence of the TP53 p.R337H mutation in breast cancer patients in Brazil
Published in PloS one (17-06-2014)“…Germline TP53 mutations predispose individuals to multiple cancers and are associated with Li-Fraumeni/Li-Fraumeni-Like Syndromes (LFS/LFL). The founder…”
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Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients
Published in Breast cancer research and treatment (01-02-2011)“…An increasing number of studies have shown altered expression of secreted protein acidic and rich in cysteine (SPARC) and N-myc down-regulated gene (NDRG1) in…”
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Evaluation of cell cycle protein expression in gastric cancer: cyclin B1 expression and its prognostic implication
Published in Human pathology (01-08-2010)“…Summary The cell cycle progression is regulated by interactions of specific cyclin-dependent kinases at the G1-S and G2-M checkpoints. In addition, the cell…”
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ERBB4 confers metastatic capacity in Ewing sarcoma
Published in EMBO molecular medicine (01-07-2013)“…Metastatic spread is the single‐most powerful predictor of poor outcome in Ewing sarcoma (ES). Therefore targeting pathways that drive metastasis has…”
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Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry
Published in BMC cancer (07-01-2009)“…Esophageal squamous cell carcinoma (ESCC) is the sixth most frequent neoplasia in Brazil. It is usually associated with a poor prognosis because it is often at…”
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Differential Expression of MicroRNAs in Leprosy Skin Lesions
Published in Frontiers in immunology (25-08-2017)“…Leprosy, a chronic infectious disease caused by , is a major public health problem in poor and developing countries of the Americas, Africa, and Asia…”
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Prognostic impact of the cancer stem cell related markers ALDH1 and EZH2 in triple negative and basal-like breast cancers
Published in Pathology (01-06-2012)“…We assessed the expression of ALDH1 and EZH2, cancer stem cell (CSC) related markers, in triple negative and basal-like breast cancers, investigating their…”
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Human salivary gland morphogenesis: myoepithelial cell maturation assessed by immunohistochemical markers
Published in Histopathology (01-09-2010)“…Ianez R F, Buim M E, Coutinho‐Camillo C M, Schultz R, Soares F A & Lourenço S V (2010) Histopathology 57, 410–417 Human salivary gland morphogenesis:…”
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Common chromosomal imbalances and stemness-related protein expression markers in endometriotic lesions from different anatomical sites: the potential role of stem cells
Published in Human reproduction (Oxford) (01-11-2012)“…BACKGROUND Endometriosis is a multifactorial gynecological disease characterized by the presence of functional endometrium-like tissue in ectopic sites…”
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Epigenetic Silencing of CRABP2 and MX1 in Head and Neck Tumors
Published in Neoplasia (New York, N.Y.) (01-12-2009)“…Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous disease affecting the epithelium of the oral cavity, pharynx and larynx. Conditions of most…”
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HOXB7 expression is a prognostic factor for oral squamous cell carcinoma
Published in Histopathology (01-03-2012)Get full text
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KRAS G12C in advanced NSCLC: Prevalence, co-mutations, and testing
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2023)“…•KRAS is the most commonly mutated oncogene in advanced NSCLCin Western countries.•KRAS G12C is the most common KRAS variant at ∼13% of NSCLC cases…”
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Diagnostic utility of DREAM gene mRNA levels in thyroid tumours
Published in Archives of Endocrinology and Metabolism (01-03-2018)“…The transcriptional repressor DREAM is involved in thyroid-specific gene expression, thyroid enlargement and nodular development, but its clinical utility is…”
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Development of human minor salivary glands: expression of mucins according to stage of morphogenesis
Published in Journal of anatomy (01-09-2011)“…The formation of salivary glands entails the proliferation of epithelial cells from the stomatodeum into the underlying ectomesenchyme, culminating in a…”
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Phyllodes tumours of the breast: a consensus review
Published in Histopathology (01-01-2016)“…Phyllodes tumours constitute an uncommon but complex group of mammary fibroepithelial lesions. Accurate and reproducible grading of these tumours has long been…”
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