Search Results - "SNABAITIS, A. K"

The role of apolipoprotein N‐acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target by Silva, R A G, Churchward, C P, Karlyshev, A V, Eleftheriadou, O, Snabaitis, A K, Longman, M R, Ryan, A, Griffin, R

“…Background and Purpose The level of cell surface expression of the meningococcal vaccine antigen, Factor H binding protein (FHbp) varies between and within…”
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Comparison of polarized and depolarized arrest in the isolated rat heart for long-term preservation by SNABAITIS, A. K, SHATTOCK, M. J, CHAMBERS, D. J

“…Hypothermic hyperkalemic cardioplegic solutions are currently used for donor heart preservation. Hyperkalemia-induced depolarization of the resting membrane…”
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Long-term myocardial preservation : Beneficial and additive effects of polarized arrest (Na+-channel blockade), Na+/H+-exchange inhibition, and Na+/K+/2Cl--cotransport inhibition combined with calcium desensitization by SNABAITIS, A. K, CHAMBERS, D. J

“…Polarized arrest, induced by tetrodotoxin (TTX) at an optimal concentration of 22 micromol/L, has been shown to reduce ionic imbalance and improve myocardial…”
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Long-term myocardial preservation: effects of hyperkalemia, sodium channel, and NA +/K +/2CL - cotransport inhibition on extracellular potassium accumulation during hypothermic storage by Snabaitis, Andrew K., Shattock, Michael J., Chambers, David J.

“…Objectives: We previously demonstrated improved myocardial preservation with polarized (tetrodotoxin-induced), compared with depolarized…”
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Roles of mitogen-activated protein kinases and protein kinase C in alpha(1A)-adrenoceptor-mediated stimulation of the sarcolemmal Na(+)-H(+) exchanger by Snabaitis, A K, Yokoyama, H, Avkiran, M

“…Activation of the sarcolemmal Na(+)-H(+) exchanger (NHE) has been implicated as a mechanism of inotropic, arrhythmogenic, antiacidotic, and hypertrophic…”
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Regulation of cardiac sarcolemmal Na+/H+ exchanger activity: potential pathophysiological significance of endogenous mediators and oxidant stress by Avkiran, M, Snabaitis, A K

“…The cardiac sarcolemmal Na(+)/H(+) exchanger (NHE) extrudes one H(+) in exchange for one Na(+) entering the myocyte, utilizing for its driving force the…”
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HYDROGEN PEROXIDE ACTIVATES THE SARCOLEMMAL NA+/H+ EXCHANGER IN ADULT VENTRICULAR MYOCYTES by Snabaitis, A K, Avkiran, M

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Long-term myocardial preservation: Beneficial and additive effects of polarized arrest (Na super(+)-channel blockade), Na super(+)/H super(+)-exchange inhibition, and Na super(+)/K super(+)/2Cl super(-)-cotransport inhibition combined with calcium desensitization by Snabaitis, A K, Chambers, D J

“…Polarized arrest, induced by tetrodotoxin (TTX) at an optimal concentration of 22 mu mol/L, has been shown to reduce ionic imbalance and improve myocardial…”
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Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway by Haworth, Robert S, McCann, Caroline, Snabaitis, Andrew K, Roberts, Neil A, Avkiran, Metin

“…Activity of the Na+/H+ exchanger (NHE) isoform 1 (NHE1) is increased by intracellular acidosis through the interaction of intracellular H+ with an allosteric…”
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Inhibition of the Na+/H+ exchanger attenuates the deterioration of ventricular function during pacing-induced heart failure in rabbits by AKER, Stephanie, SNABAITIS, Andrew K, KONIETZKA, Ina, VAN DE SAND, Anita, BÖNGLER, Kerstin, AVKIRAN, Metin, HEUSCH, Gerd, SCHULZ, Rainer

“…Inhibition of the Na+/H+-exchanger (NHE) preserves myocardial morphology and function in rat and mouse models of hypertrophy and failure. The mechanism(s)…”
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Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes by Snabaitis, Andrew K, Hearse, David J, Avkiran, Metin

“…To characterise the effects of exogenous H(2)O(2) on sarcolemmal Na(+)/H(+) exchanger (NHE) activity and determine the roles of extracellular signal-regulated…”
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Roles of Mitogen-Activated Protein Kinases and Protein Kinase C in α1A-Adrenoceptor–Mediated Stimulation of the Sarcolemmal Na+-H+ Exchanger by Snabaitis, Andrew K, Yokoyama, Hiroyuki, Avkiran, Metin

“…ABSTRACTActivation of the sarcolemmal Na-H exchanger (NHE) has been implicated as a mechanism of inotropic, arrhythmogenic, antiacidotic, and hypertrophic…”
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