Search Results - "SMITH, LEON"

Gene transfer to plants by diverse species of bacteria by Broothaerts, W, Mitchell, H.J, Weir, B, Kaines, S, Smith, L.M.A, Yang, W, Mayer, J.E, Roa-Rodriguez, C, Jefferson, R.A

“…Agrobacterium is widely considered to be the only bacterial genus capable of transferring genes to plants. When suitably modified, Agrobacterium has become the…”
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Symbiotic gut microbes modulate human metabolic phenotypes by Li, Min, Wang, Baohong, Zhang, Menghui, Rantalainen, Mattias, Wang, Shengyue, Zhou, Haokui, Zhang, Yan, Shen, Jian, Pang, Xiaoyan, Zhang, Meiling, Wei, Hua, Chen, Yu, Lu, Haifeng, Zuo, Jian, Su, Mingming, Qiu, Yunping, Jia, Wei, Xiao, Chaoni, Smith, Leon M, Yang, Shengli, Holmes, Elaine, Tang, Huiru, Zhao, Guoping, Nicholson, Jeremy K, Li, Lanjuan, Zhao, Liping

“…Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host…”
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Host specialisation and disparate evolution of Pyrenophora teres f. teres on barley and barley grass by Linde, Celeste C, Smith, Leon M

“…Pathogens evolve in an arms race, frequently evolving virulence that defeats resistance genes in their hosts. Infection of multiple hosts may accelerate this…”
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Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212) by Pinto, Donald J. P., Orwat, Michael J., Smith, Leon M., Quan, Mimi L., Lam, Patrick Y. S., Rossi, Karen A., Apedo, Atsu, Bozarth, Jeffrey M., Wu, Yiming, Zheng, Joanna J., Xin, Baomin, Toussaint, Nathalie, Stetsko, Paul, Gudmundsson, Olafur, Maxwell, Brad, Crain, Earl J., Wong, Pancras C., Lou, Zhen, Harper, Timothy W., Chacko, Silvi A., Myers, Joseph E., Sheriff, Steven, Zhang, Huiping, Hou, Xiaoping, Mathur, Arvind, Seiffert, Dietmar A., Wexler, Ruth R., Luettgen, Joseph M., Ewing, William R.

“…Factor XIa (FXIa) is a blood coagulation enzyme that is involved in the amplification of thrombin generation. Mounting evidence suggests that direct inhibition…”
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Simultaneous Pulmonary Embolism and Carotid Thrombosis as a Presenting Manifestation of COVID-19 by Smith, Leon, Zeman, Brian

“…Although COVID-19 was initially described predominantly as a respiratory infection, subsequent reports noted that it can produce generalised inflammation with…”
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Weeds, as ancillary hosts, pose disproportionate risk for virulent pathogen transfer to crops by Linde, Celeste C, Smith, Leon M, Peakall, Rod

“…The outcome of the arms race between hosts and pathogens depends heavily on the interactions between their genetic diversity, population size and transmission…”
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Nanoparticles for MRI-guided radiation therapy: a review by Smith, Leon, Byrne, Hilary L., Waddington, David, Kuncic, Zdenka

“…The development of nanoparticle agents for MRI-guided radiotherapy is growing at an increasing pace, with clinical trials now underway and many pre-clinical…”
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Periventricular cyst as a complication of ventriculoperitoneal shunting in the context of intracranial haemorrhage: a case report and review of the literature by Smith, Leon E, Zeman, Brian D

“…Abstract Spontaneous intraventricular haemorrhage with hydrocephalus frequently requires neurosurgical intervention, including ventriculoperitoneal shunting…”
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High-Dose, Short-Course Levofloxacin for Community-Acquired Pneumonia: A New Treatment Paradigm by Dunbar, Lala M, Wunderink, Richard G, Habib, Michael P, Smith, Leon G, Tennenberg, Alan M, Khashab, Mohammed M, Wiesinger, Barbara A, Xiang, Jim X, Zadeikis, Neringa, Kahn, James B

“…Levofloxacin demonstrates concentration-dependent bactericidal activity most closely related to the pharmacodynamic parameters of the ratio of area under the…”
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A mild and readily scalable procedure for the N-1-difluoromethylation of ethyl 6-((tert-butyldiphenylsilyl)oxy)-1H-indazole-3-carboxylate and its applications to the N-difluoromethylation of indazole, benzotriazole, imidazole, indole and pyrazole derivatives by Hong, Zhenqiu, Hou, Xiaoping, Zhao, Rulin, Li, Jianqing, Pawluczyk, Joseph, Wang, Bei, Kempson, James, Khandelwal, Purnima, Smith, Leon M., Glunz, Peter, Mathur, Arvind

“…[Display omitted] •Mild condition.•Scalable.•Suitable for substartes bearing labile groups. A set of mild conditions for the N-1-difluoromethylation of ethyl…”
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Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties by Pinto, Donald J.P., Smallheer, Joanne M., Corte, James R., Austin, Erin J.D., Wang, Cailan, Fang, Tianan, Smith, Leon M., Rossi, Karen A., Rendina, Alan R., Bozarth, Jeffrey M., Zhang, Ge, Wei, Anzhi, Ramamurthy, Vidhyashankar, Sheriff, Steven, Myers, Joseph E., Morin, Paul E., Luettgen, Joseph M., Seiffert, Dietmar A., Quan, Mimi L., Wexler, Ruth R.

“…[Display omitted] Compound 2 was previously identified as a potent inhibitor of factor XIa lacking oral bioavailability. A structure-based approach was used to…”
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Correction: Nanoparticles for MRI-guided radiation therapy: a review by Smith, Leon, Byrne, Hilary L., Waddington, David, Kuncic, Zdenka

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New species of Tulasnella associated with terrestrial orchids in Australia by Linde, Celeste C, May, Tom W, Phillips, Ryan D, Ruibal, Monica, Smith, Leon M, Peakall, Rod

“…Recent studies using sequence data from eight sequence loci and coalescent-based species delimitation methods have revealed several species-level lineages of…”
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Novel phenylalanine derived diamides as Factor XIa inhibitors by Smith, Leon M., Orwat, Michael J., Hu, Zilun, Han, Wei, Wang, Cailan, Rossi, Karen A., Gilligan, Paul J., Pabbisetty, Kumar B., Osuna, Honey, Corte, James R., Rendina, Alan R., Luettgen, Joseph M., Wong, Pancras C., Narayanan, Ranga, Harper, Timothy W., Bozarth, Jeffrey M., Crain, Earl J., Wei, Anzhi, Ramamurthy, Vidhyashankar, Morin, Paul E., Xin, Baomin, Zheng, Joanna, Seiffert, Dietmar A., Quan, Mimi L., Lam, Patrick Y.S., Wexler, Ruth R., Pinto, Donald J.P.

“…[Display omitted] The synthesis, structural activity relationships (SAR), and selectivity profile of a potent series of phenylalanine diamide FXIa inhibitors…”
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narrow group of monophyletic Tulasnella (Tulasnellaceae) symbiont lineages are associated with multiple species of Chiloglottis (Orchidaceae): Implications for orchid diversity by Roche, Sean A, Carter, Richard J, Peakall, Rod, Smith, Leon M, Whitehead, Michael R, Linde, Celeste C

“…Premise of the study: The Orchidaceae is characterized by exceptional species diversity. Obligate orchid mycorrhizae are predicted to determine orchid…”
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Mycoplasma Pneumonia and Its Complications by Smith, Leon G., MD, MACP

“…Mycoplasma pneumoniae continues to be the most frequent cause of atypical pneumonia. Fortunately, the antibiotics listed in this article are generally very…”
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The Competency Movement Within Psychology: An Historical Perspective by Rubin, Nancy J, Bebeau, Muriel, Leigh, Irene W, Lichtenberg, James W, Nelson, Paul D, Portnoy, Sanford, Smith, I. Leon, Kaslow, Nadine J

“…The authors provide a recitation of events in recent years that document an increased focus on competency-based models of education, training, and assessment…”
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Statistical Correlation and Projection Methods for Improved Information Recovery from Diffusion-Edited NMR Spectra of Biological Samples by Smith, Leon M, Maher, Anthony D, Cloarec, Olivier, Rantalainen, Mattias, Tang, Huiru, Elliott, Paul, Stamler, Jeremiah, Lindon, John C, Holmes, Elaine, Nicholson, Jeremy K

“…Although NMR spectroscopic techniques coupled with multivariate statistics can yield much useful information for classifying biological samples based on…”
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Worldwide Assessment of Linezolid's Clinical Safety and Tolerability: Comparator-Controlled Phase III Studies by Rubinstein, Ethan, Isturiz, Raul, Standiford, Harold C, Smith, Leon G, Oliphant, Thomas H, Cammarata, Sue, Hafkin, Barry, Le, Vu, Remington, Jack

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Tetraplegic spinal cord injury as a presentation of multiple myeloma: A case report by Smith, Leon Edward, Li, Vicky Ying, Chan, Simon

“…Key Clinical Message Spinal cord injury is a devastating complication of cancers that exert physical compression on the spinal cord. Multiple myeloma is known…”
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