Search Results - "SMITH, Gavin J"

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic by Guan, Yi, Rambaut, Andrew, Smith, Gavin J. D, Vijaykrishna, Dhanasekaran, Bahl, Justin, Lycett, Samantha J, Worobey, Michael, Pybus, Oliver G, Ma, Siu Kit, Cheung, Chung Lam, Raghwani, Jayna, Bhatt, Samir, Peiris, J. S. Malik

“…In March and early April 2009, a new swine-origin influenza A (H1N1) virus (S-OIV) emerged in Mexico and the United States. During the first few weeks of…”
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RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion by Vijaykrishna, Dhanasekaran, Mukerji, Reshmi, Smith, Gavin J D

“…  Virus reassortment, or simply reassortment, is a process of genetic recombination that is exclusive to segmented RNA viruses in which co-infection of a host…”
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Determinants of influenza and pneumococcal vaccine uptake among preschool children in Singapore by Zahari, Marina, Offeddu, Vittoria, Smith, Gavin J D, Tam, Clarence C

“…Young children are at increased risk of severe illness from influenza and pneumococcal infections. The World Health Organization (WHO) recommends vaccination…”
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Evidence for antigenic seniority in influenza A (H3N2) antibody responses in southern China by Lessler, Justin, Riley, Steven, Read, Jonathan M, Wang, Shuying, Zhu, Huachen, Smith, Gavin J D, Guan, Yi, Jiang, Chao Qiang, Cummings, Derek A T

“…A key observation about the human immune response to repeated exposure to influenza A is that the first strain infecting an individual apparently produces the…”
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Nomenclature updates resulting from the evolution of avian influenza A(H5) virus clades 2.1.3.2a, 2.2.1, and 2.3.4 during 2013–2014 by Smith, Gavin J. D., Donis, Ruben O.

“…Aim The A/goose/Guangdong/1/96‐like hemagglutinin (HA) genes of highly pathogenic avian influenza (HPAI) A(H5) viruses have continued to rapidly evolve since…”
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Long-term evolution and transmission dynamics of swine influenza A virus by Vijaykrishna, Dhanasekaran, Smith, Gavin J. D., Pybus, Oliver G., Zhu, Huachen, Bhatt, Samir, Poon, Leo L. M., Riley, Steven, Bahl, Justin, Ma, Siu K., Cheung, Chung L., Perera, Ranawaka A. P. M., Chen, Honglin, Shortridge, Kennedy F., Webby, Richard J., Webster, Robert G., Guan, Yi, Peiris, J. S. Malik

“…Swine flu surveillance in pigs Pigs are recognized as important 'mixing vessels' in which influenza viruses can undergo reassortment, but despite the resulting…”
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Ecological Drivers of Virus Evolution: Astrovirus as a Case Study by Mendenhall, Ian H, Smith, Gavin J D, Vijaykrishna, Dhanasekaran

“…Although RNA viruses exhibit a high frequency of host jumps, major differences exist among the different virus families. Astroviruses infect a wide range of…”
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Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans by Bahl, Justin, Nelson, Martha I, Chan, Kwok H, Chen, Rubing, Vijaykrishna, Dhanasekaran, Halpin, Rebecca A, Stockwell, Timothy B, Lin, Xudong, Wentworth, David E, Ghedin, Elodie, Guan, Yi, Peiris, J. S. Malik, Riley, Steven, Rambaut, Andrew, Holmes, Edward C, Smith, Gavin J. D

“…Populations of seasonal influenza virus experience strong annual bottlenecks that pose a considerable extinction risk. It has been suggested that an influenza…”
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Dating the emergence of pandemic influenza viruses by Smith, Gavin J.D, Bahl, Justin, Vijaykrishna, Dhanasekaran, Zhang, Jinxia, Poon, Leo L.M, Chen, Honglin, Webster, Robert G, Peiris, J.S. Malik, Guan, Yi

“…Pandemic influenza viruses cause significant mortality in humans. In the 20th century, 3 influenza viruses caused major pandemics: the 1918 H1N1 virus, the…”
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Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover by Dovih, Pilot, Laing, Eric D, Chen, Yihui, Low, Dolyce H W, Ansil, B R, Yang, Xinglou, Shi, Zhengli, Broder, Christopher C, Smith, Gavin J D, Linster, Martin, Ramakrishnan, Uma, Mendenhall, Ian H

“…Bats are reservoirs for several zoonotic pathogens, including filoviruses. Recent work highlights the diversity of bat borne filoviruses in Asia. High risk…”
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TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection by Yousefi, Meisam, Lee, Wai Suet, Yan, Biaoguo, Cui, Liang, Yong, Cythia Lingli, Yap, Xin, Tay, Kwan Sing Leona, Qiao, Wenjie, Tan, Dewei, Nurazmi, Nur Insyirah, Linster, Martin, Smith, Gavin J. D, Lee, Yie Hou, Carette, Jan E, Ooi, Eng Eong, Chan, Kuan Rong, Ooi, Yaw Shin

“…Transmembrane Protein 41B (TMEM41B) and Vacuole Membrane Protein 1 (VMP1) are two ER-associated lipid scramblases that play a role in autophagosome formation…”
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Human Infection with an Avian H9N2 Influenza A Virus in Hong Kong in 2003 by Butt, K. M, Smith, Gavin J. D, Chen, Honglin, Zhang, L. J, Leung, Y. H. Connie, Xu, K. M, Lim, Wilina, Webster, Robert G, Yuen, K. Y, Peiris, J. S. Malik, Guan, Yi

“…Avian H9N2 influenza A virus has caused repeated human infections in Asia since 1998. Here we report that an H9N2 influenza virus infected a 5-year-old child…”
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The effective rate of influenza reassortment is limited during human infection by Sobel Leonard, Ashley, McClain, Micah T, Smith, Gavin J D, Wentworth, David E, Halpin, Rebecca A, Lin, Xudong, Ransier, Amy, Stockwell, Timothy B, Das, Suman R, Gilbert, Anthony S, Lambkin-Williams, Rob, Ginsburg, Geoffrey S, Woods, Christopher W, Koelle, Katia, Illingworth, Christopher J R

“…We characterise the evolutionary dynamics of influenza infection described by viral sequence data collected from two challenge studies conducted in human…”
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Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2 by Su, Yvonne C F, Anderson, Danielle E, Young, Barnaby E, Linster, Martin, Zhu, Feng, Jayakumar, Jayanthi, Zhuang, Yan, Kalimuddin, Shirin, Low, Jenny G H, Tan, Chee Wah, Chia, Wan Ni, Mak, Tze Minn, Octavia, Sophie, Chavatte, Jean-Marc, Lee, Raphael T C, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Yan, Gabriel Z, Maurer-Stroh, Sebastian, Mendenhall, Ian H, Leo, Yee-Sin, Lye, David Chien, Wang, Lin-Fa, Smith, Gavin J D

“…To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. Here, we report a…”
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Distribution of Amantadine-Resistant H5N1 Avian Influenza Variants in Asia by Cheung, Chung-Lam, Rayner, Jane M., Smith, Gavin J. D., Wang, Pui, Naipospos, T. S. P., Zhang, Jinxia, Yuen, Kwok-Yung, Webster, Robert G., Peiris, J. S. Malik, Guan, Yi, Chen, Honglin

“…We examined the distribution of genetic mutations associated with resistance to the M2 ion channel–blocking adamantane derivatives, amantadine and rimantadine,…”
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Ancient origins determine global biogeography of hot and cold desert cyanobacteria by Pointing, Stephen B, Bahl, Justin, Lau, Maggie C. Y, Smith, Gavin J. D, Vijaykrishna, Dhanasekaran, Cary, S. Craig, Lacap, Donnabella C, Lee, Charles K, Papke, R. Thane, Warren-Rhodes, Kimberley A, Wong, Fiona K. Y, McKay, Christopher P

“…Factors governing large-scale spatio-temporal distribution of microorganisms remain unresolved, yet are pivotal to understanding ecosystem value and function…”
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Mapping Platform Urbanism: Charting the Nuance of the Platform Pivot by Lee, Ashlin, Mackenzie, Adrian, J. D. Smith, Gavin, Box, Paul

“…Urban planners are increasingly working with ideas around datafied cities, such as platform urbanism, to understand urban life and changes with technology…”
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Evolutionary dynamics and emergence of panzootic H5N1 influenza viruses by Vijaykrishna, Dhanasekaran, Bahl, Justin, Riley, Steven, Duan, Lian, Zhang, Jin Xia, Chen, Honglin, Peiris, J S Malik, Smith, Gavin J D, Guan, Yi

“…The highly pathogenic avian influenza (HPAI) H5N1 virus lineage has undergone extensive genetic reassortment with viruses from different sources to produce…”
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Prevalence and Phylogenetics of H9n2 in Backyard and Commercial Poultry in Pakistan by Ali, Muzaffar, Yaqub, Tahir, Mukhtar, Nadia, Imran, Muhammad, Ghafoor, Aamir, Shahid, Muhammad Furqan, Yaqub, Saima, Smith, Gavin J. D, Su, Yvonne C. F, Naeem, Muhammad

“…Surveillance of H9N2 is currently focused on areas central to the commercial poultry industry. This study determined the prevalence of H9N2 virus in commercial…”
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Ecosystem Interactions Underlie the Spread of Avian Influenza A Viruses with Pandemic Potential by Bahl, Justin, Pham, Truc T, Hill, Nichola J, Hussein, Islam T M, Ma, Eric J, Easterday, Bernard C, Halpin, Rebecca A, Stockwell, Timothy B, Wentworth, David E, Kayali, Ghazi, Krauss, Scott, Schultz-Cherry, Stacey, Webster, Robert G, Webby, Richard J, Swartz, Michael D, Smith, Gavin J D, Runstadler, Jonathan A

“…Despite evidence for avian influenza A virus (AIV) transmission between wild and domestic ecosystems, the roles of bird migration and poultry trade in the…”
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