Search Results - "SMITH, D. I"

Heterogeneity in Vaccine Immune Response: The Role of Immunogenetics and the Emerging Field of Vaccinomics by Poland, G A, Ovsyannikova, I G, Jacobson, R M, Smith, D I

“…Recent advances in the fields of immunology, genetics, molecular biology, bioinformatics, and the Human Genome Project have allowed for the emergence of the…”
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RORA, a large common fragile site gene, is involved in cellular stress response by ZHU, Y, MCAVOY, S, KUHN, R, SMITH, D. I

“…Common fragile sites (CFSs) are large genomic regions present in all individuals that are highly unstable and prone to breakage and rearrangement, especially…”
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Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1 by Chung, T.K.H., Lau, T.S., Cheung, T.H., Yim, S.F., Lo, K.W.K., Siu, N.S.S., Chan, L.K.Y., Yu, M.Y., Kwong, J., Doran, G., Barroilhet, L.M., Ng, A.S.W., Wong, R.R.Y., Wang, V.W., Mok, S.C., Smith, D.I., Berkowitz, R.S., Wong, Y.F.

“…MicroRNAs (miRNAs) regulate mRNA stability and protein expression, and certain miRNAs have been demonstrated to act either as oncogenes or tumor suppressors…”
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Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling by WONG, Y. F, CHEUNG, T. H, LI, C, GARDNER, G. J, BONOME, T, JOHNSON, W. B, SMITH, D. I, CHUNG, T. K. H, BIRRER, M. J, LO, K. W. K, YIM, S. F, SIU, N. S. S, CHAN, S. C. S, HO, T. W. F, WONG, K. W. Y, YU, M. Y, WANG, V. W

“…Endometrial cancer is the third most common gynecologic malignancy and the ninth most common malignancy for females overall in Hong Kong. Approximately 80% or…”
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Integrations of the hepatitis B virus (HBV) and human papillomavirus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers by FERBER, M. J, MONTOYA, D. P, BRUIX, J, MCMAHON, B. J, CHEUNG, T. H, CHUNG, T. K. H, WONG, Y. F, SMITH, D. I, ROBERTS, L. R, YU, C, ADERCA, I, MCGEE, A, THORLAND, E. C, NAGORNEY, D. M, GOSTOUT, B. S, BURGART, L. J, BOIX, L

“…Chronic infections with the hepatitis B virus (HBV) and high-risk human papillomaviruses (HPVs) are important risk factors for hepatocellular carcinoma (HCC)…”
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Differences between subjective and objective assessments of the utility of Electroconvulsive therapy in patients with bipolar and unipolar depression by Hallam, K.T, Smith, D.I, Berk, M

“…Abstract While ECT is widely used for the management of severe and refractory depression, its utility in bipolar disorder is not extensively studied. The aim…”
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Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations by Liu, Wanguo, Smith, David I., Rechtzigel, Keri J., Thibodeau, Stephen N., James, C. David

“…Denaturing high performance liquid chromatography (DHPLC) has been described recently as a method for screening DNA samples for single nucleotide polymorphisms…”
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Climate change impacts on urban flooding by SCHREIDER, S. Yu, SMITH, D. I, JAKEMAN, A. J

“…This paper estimates changes in the potential damage of flood events caused by increases of CO2 concentration in the atmosphere. It is presented in two parts:…”
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Human papillomavirus type 16 integrations in cervical tumors frequently occur in common fragile sites by THORLAND, Erik C, MYERS, Shannon L, PERSING, David H, SARKAR, Gobinda, MCGOVERN, Renee M, GOSTOUT, Bobbie S, SMITH, David I

“…The development of cervical cancer is highly associated with human papillomavirus (HPV) infection. HPV integration into the genome of infected cervical cells…”
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Non-random inactivation of large common fragile site genes in different cancers by McAvoy, S, Ganapathiraju, S C, Ducharme-Smith, A L, Pritchett, J R, Kosari, F, Perez, D S, Zhu, Y, James, C D, Smith, D I

“…The common fragile sites are regions of profound genomic instability found in all individuals. The full size of each region of instability ranges from under…”
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Activation of p73 silent allele in lung cancer by MING MAI, YOKOMIZO, A, CHIPING QIAN, PING YANG, TINDALL, D. J, SMITH, D. I, WANGUO LIU

“…p73, a first p53 relative, has recently been identified and demonstrated to be monoallelically expressed. This protein shows significant amino acid sequence…”
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Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer by Kawakami, M, Staub, J, Cliby, W, Hartmann, L, Smith, D I, Shridhar, V

“…Ovarian cancer is one of the leading causes of mortality unique to women. Deletions within chromosome 6q are the most frequent events in high-grade invasive…”
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Uranium series isotopes in the Avon Valley, Nova Scotia by Kronfeld, J, Godfrey-Smith, D.I, Johannessen, D, Zentilli, M

“…An U-series isotopic study was carried out in the waters of the Avon Valley, Nova Scotia. The fresh and acidic recharge waters flow rapidly through the…”
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Effects of chronic fluoxetine treatment in the presence and absence of (±)pindolol: a microdialysis study by Dawson, L A, Nguyen, H Q, Smith, D I, Schechter, L E

“…Using in vivo microdialysis in the frontal cortex of the freely moving rat we evaluated the effects of chronic treatment with the serotonin specific reuptake…”
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Replication of a Common Fragile Site, FRA3B, Occurs Late in S Phase and is Delayed Further Upon Induction: Implications for the Mechanism of Fragile Site Induction by Le Beau, Michelle M., Rassool, Feyruz V., Neilly, Mary E., Espinosa, Rafael, Glover, Thomas W., Smith, David I., McKeithan, Timothy W.

“…The FRA3B at 3p14.2 is the most highly expressed of the common fragile sites observed when DNA replication is perturbed by aphidicolin or folate stress. The…”
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PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers by YOKOMIZO, A, TINDALL, D. J, DRABKIN, H, GEMMILL, R, FRANKLIN, W, PING YANG, SUGIO, K, SMITH, D. I, WANGUO LIU

“…A putative tumor suppressor, PTEN/MMAC1 gene at 10q23 was recently identified and found to be mutated in many different human tumors. To determine the role of…”
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THE ORIGIN, DESTRUCTION AND RESTORATION OF COLOUR IN EGYPTIAN TRAVERTINE by HARRELL, J. A., BROEKMANS, M. A. T. M., GODFREY-SMITH, D. I.

“…Travertine was one of ancient Egypt's most popular ornamental stones. Upon prolonged exposure to sunlight, the rock's translucent brownish calcite is bleached…”
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FRA3B Extends Over a Broad Region and Contains a Spontaneous HPV16 Integration Site: Direct Evidence for the Coincidence of Viral Integration Sites and Fragile Sites by Wilke, Charles M., Hall, Bryan K., Hoge, Ann, Paradee, William, Smith, David I., Glover, Thomas W.

“…The common fragile site at 3p14.2 (FRA3B) is the most sensitive site on normal human chromosomes for the formation of gaps and breaks when DNA replication is…”
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Twenty-year weathering remeasurements at St Paul's Cathedral, London by Trudgill, S. T., Viles, H. A., Inkpen, R., Moses, C., Gosling, W., Yates, T., Collier, P., Smith, D. I., Cooke, R. U.

“…Microerosion meter (MEM) measurements of the surface height of the balustrade of St Paul's Cathedral, London, have been repeated in the year 2000 following…”
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DMD and IL1RAPL1: two large adjacent genes localized within a common fragile site (FRAXC) have reduced expression in cultured brain tumors by McAvoy, S, Ganapathiraju, S, Perez, D S, James, C D, Smith, D I

“…Common fragile sites (CFSs) are large regions of profound genomic instability found in all individuals. Spanning the center of the two most frequently…”
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