Search Results - "SMIT, Frank P"

Detection of High-grade Prostate Cancer Using a Urinary Molecular Biomarker–Based Risk Score by Van Neste, Leander, Hendriks, Rianne J, Dijkstra, Siebren, Trooskens, Geert, Cornel, Erik B, Jannink, Sander A, de Jong, Hans, Hessels, Daphne, Smit, Frank P, Melchers, Willem J.G, Leyten, Gisèle H.J.M, de Reijke, Theo M, Vergunst, Henk, Kil, Paul, Knipscheer, Ben C, Hulsbergen-van de Kaa, Christina A, Mulders, Peter F.A, van Oort, Inge M, Van Criekinge, Wim, Schalken, Jack A

“…Abstract Background To reduce overdiagnosis and overtreatment, a test is urgently needed to detect clinically significant prostate cancer (PCa). Objective To…”
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Identification of a Candidate Gene Panel for the Early Diagnosis of Prostate Cancer by Leyten, Gisele H J M, Hessels, Daphne, Smit, Frank P, Jannink, Sander A, de Jong, Hans, Melchers, Willem J G, Cornel, Erik B, de Reijke, Theo M, Vergunst, Henk, Kil, Paul, Knipscheer, Ben C, Hulsbergen-van de Kaa, Christina A, Mulders, Peter F A, van Oort, Inge M, Schalken, Jack A

“…Serum PSA (sPSA) testing has led to the identification of patients with indolent prostate cancer, and inevitably overtreatment has become a concern. Progensa…”
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Prospective Multicentre Evaluation of PCA3 and TMPRSS2-ERG Gene Fusions as Diagnostic and Prognostic Urinary Biomarkers for Prostate Cancer by Leyten, Gisele H.J.M, Hessels, Daphne, Jannink, Sander A, Smit, Frank P, de Jong, Hans, Cornel, Erik B, de Reijke, Theo M, Vergunst, Henk, Kil, Paul, Knipscheer, Ben C, van Oort, Inge M, Mulders, Peter F.A, Hulsbergen-van de Kaa, Christina A, Schalken, Jack A

“…Abstract Background Prostate cancer antigen 3 ( PCA3 ) and v-ets erythroblastosis virus E26 oncogene homolog ( TMPRSS2-ERG ) gene fusions are promising…”
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Prostate cancer biomarker profiles in urinary sediments and exosomes by Dijkstra, Siebren, Birker, Ingrid L, Smit, Frank P, Leyten, Gisele H J M, de Reijke, Theo M, van Oort, Inge M, Mulders, Peter F A, Jannink, Sander A, Schalken, Jack A

“…Urinary biomarker tests for diagnosing prostate cancer have gained considerable interest. Urine is a complex mixture that can be subfractionated. We evaluated…”
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Detection of TMPRSS2-ERG Fusion Transcripts and Prostate Cancer Antigen 3 in Urinary Sediments May Improve Diagnosis of Prostate Cancer by HESSELS, Daphne, SMIT, Frank P, VERHAEGH, Gerald W, WITJES, J. Alfred, CORNET, Erik B, SCHALKEN, Jack A

“…Purpose: Early detection of prostate cancer can increase the curative success rate for prostate cancer. We studied the diagnostic usefulness of TMPRSS2-ERG…”
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Epigenetic markers in circulating cell‐free DNA as prognostic markers for survival of castration‐resistant prostate cancer patients by Hendriks, Rianne J., Dijkstra, Siebren, Smit, Frank P., Vandersmissen, Johan, Van de Voorde, Hendrik, Mulders, Peter F. A., van Oort, Inge M., Van Criekinge, Wim, Schalken, Jack A.

“…Background : Noninvasive biomarkers to guide personalized treatment for castration‐resistant prostate cancer (CRPC) are needed. In this study, we analyzed…”
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Androgen receptor signalling confers clonogenic and migratory advantages in urothelial cell carcinoma of the bladder by Luna‐Velez, Maria V., Dijkstra, Jelmer J., Heuschkel, Marina A., Smit, Frank P., van de Zande, Guillaume, Smeets, Dominique, Sedelaar, J. P. Michiel, Vermeulen, Michiel, Verhaegh, Gerald W., Schalken, Jack A.

“…Bladder urothelial cell carcinoma (UCC) incidence is about three times higher in men compared with women. There are several indications for the involvement of…”
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The Androgen Regulated lncRNA NAALADL2-AS2 Promotes Tumor Cell Survival in Prostate Cancer by Groen, Levi, Yurevych, Viktor, Ramu, Harshitha, Chen, Johnny, Steenge, Lianne, Boer, Sabrina, Kuiper, Renske, Smit, Frank P, Verhaegh, Gerald W, Mehra, Niven, Schalken, Jack A

“…Castration resistance is the leading cause of death in men with prostate cancer. Recent studies indicate long noncoding RNAs (lncRNAs) to be important drivers…”
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Prevalence of human xenotropic murine leukemia virus-related gammaretrovirus (XMRV) in dutch prostate cancer patients by Verhaegh, Gerald W., de Jong, Arjan S., Smit, Frank P., Jannink, Sander A., Melchers, Willem J.G., Schalken, Jack A.

“…BACKGROUND The occurrence of the retrovirus xenotropic murine leukemia virus (MLV)‐related virus (XMRV) has been reported in prostate tissue of patients with…”
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Steroidogenic Enzymes and Stem Cell Markers Are Upregulated during Androgen Deprivation in Prostate Cancer by Pfeiffer, Minja J, Smit, Frank P, Sedelaar, John P M, Schalken, Jack A

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Discovery of RNA Biomarkers for Prostate Cancer Using Cross-Platform Transcriptomics by Visser, Wieke C. H., de Jong, Hans, Smit, Frank P., Shrivastava, Jolly, Poole, Jason C., Leenders, William P. J., Melchers, Willem J. G., Mulders, Peter F. A., Schalken, Jack A.

“…Microarray and Single-Molecule Molecular Inversion Probe (smMIP)-based targeted RNA sequencing are two RNA profiling platforms for identifying…”
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miRNA-520f Reverses Epithelial-to-Mesenchymal Transition by Targeting ADAM9 and TGFBR2 by van Kampen, Jasmijn G M, van Hooij, Onno, Jansen, Cornelius F, Smit, Frank P, van Noort, Paula I, Schultz, Iman, Schaapveld, Roel Q J, Schalken, Jack A, Verhaegh, Gerald W

“…Reversing epithelial-to-mesenchymal transition (EMT) in cancer cells has been widely considered as an approach to combat cancer progression and therapeutic…”
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Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer by Pfeiffer, Minja J, Smit, Frank P, Sedelaar, John P M, Schalken, Jack A

“…Considerable levels of testosterone and dihydrotestosterone (DHT) are found in prostate cancer (PCa) tissue after androgen deprivation therapy. Treatment of…”
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High‐resolution ERG‐expression profiling on GeneChip exon 1.0 ST arrays in primary and castration‐resistant prostate cancer by Smit, Frank P., Salagierski, Maciej, Jannink, Sander, Schalken, Jack A.

“…Objective To assess whether oestrogen‐regulated gene (ERG) expression analysis using GeneChip arrays can predict transmembrane protease, serine 2 (TMPRSS2)‐ERG…”
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Dutasteride and Enzalutamide Synergistically Suppress Prostate Tumor Cell Proliferation by Hamid, Agus Rizal A.H, Verhaegh, Gerald W, Smit, Frank P, van Rijt-van de Westerlo, Cindy, Armandari, Inna, Brandt, Andre, Sweep, Fred C.G.J, Sedelaar, John P.M, Schalken, Jack A

“…Purpose Dihydrotestosterone is the main active androgen in the prostate and it has a role in prostate cancer progression. After androgen deprivation therapy…”
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DD3 : A new prostate-specific gene, highly overexpressed in prostate cancer by BUSSEMAKERS, M. J. G, VAN BOKHOVEN, A, VERHAEGH, G. W, SMIT, F. P, KARTHAUS, H. F. M, SCHALKEN, J. A, DEBRUYNE, F. M. J, NING RU, ISAACS, W. B

“…Prostate cancer is the most commonly diagnosed malignancy and the second leading cause of cancer-related deaths in the Western male population. Despite the…”
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Differential expression of PCA3 and its overlapping PRUNE2 transcript in prostate cancer by Salagierski, Maciej, Verhaegh, Gerald W., Jannink, Sander A., Smit, Frank P., Hessels, Daphne, Schalken, Jack A.

“…BACKGROUND PCA3 is one of the most prostate cancer (PrCa)‐specific markers described so far. Recently, a new genomic structure of PCA3 as well as new flanking…”
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Broadband Diversity Antenna Array for UHF Digital TV by Edson T. C., Dos Santos, Daniel H. M., De Souza, Perotoni, Marcelo B., Bordin, Claudio J., Vieira, Marcos S., Frank L. P., Smit, Akamine, Cristiano

“…This article describes the design and test of a UHF broadband array antenna for applications in Digital Terrestrial TV Broadcasting (DTTB) TV 3.0 project…”
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The Androgen Regulated lncRNA INAALADL2-AS2/I Promotes Tumor Cell Survival in Prostate Cancer by Groen, Levi, Yurevych, Viktor, Ramu, Harshitha, Chen, Johnny, Steenge, Lianne, Boer, Sabrina, Kuiper, Renske, Smit, Frank P, Verhaegh, Gerald W, Mehra, Niven, Schalken, Jack A

“…Castration resistance is the leading cause of death in men with prostate cancer. Recent studies indicate long noncoding RNAs (lncRNAs) to be important drivers…”
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High‐resolution ERG ‐expression profiling on G eneChip exon 1.0 ST arrays in primary and castration‐resistant prostate cancer by Smit, Frank P., Salagierski, Maciej, Jannink, Sander, Schalken, Jack A.

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