Search Results - "SMIBERT, C. A"

smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo by Smibert, C A, Wilson, J E, Kerr, K, Macdonald, P M

“…nanos mRNA, which encodes the localized component of the Drosophila posterior body patterning determinant, is normally translated only at the posterior pole of…”
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Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs by SMIBERT, C. A, POPOVA, B, XIAO, P, CAPONE, J. P, SMILEY, J. R

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Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff function by Lam, Q., Smibert, C. A., Koop, K. E., Lavery, C., Capone, J. P., Weinheimer, S. P., Smiley, J. R.

“…Herpes simplex virus (HSV) virions contain two regulatory proteins that facilitate the onset of the lytic cycle: VP16 activates transcription of the viral…”
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Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins by Jones, F E, Smibert, C A, Smiley, J R

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Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41 by Smibert, Craig A, Johnson, David C, Smiley, James R

“…Molecular Virology and Immunology Program, McMaster University, Hamilton, Ontario L8N 3Z5, Canada The virion-induced host shutoff product of the herpes simplex…”
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Mechanisms of RNA localization and translational regulation by Lipshitz, Howard D, Smibert, Craig A

“…Transcript localization and translational regulation are two post-transcriptional mechanisms for the spatial and temporal regulation of protein production…”
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Differential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant by Smibert, C A, Smiley, J R

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Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro by SMIBERT, CRAIG A., LIE, YUNG S., SHILLINGLAW, WENDY, HENZEL, WILLIAM J., MACDONALD, PAUL M.

“…Proper deployment of Nanos protein at the posterior of the Drosophila embryo, where it directs posterior development, requires a combination of RNA…”
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Translational regulation of maternal mRNAs by Macdonald, Paul M, Smibert, Craig A

“…Translational regulation of maternal mRNAs serves to constrain their activities in both time and space. Both types of constraint might be expected to be…”
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SMAUG Is a Major Regulator of Maternal mRNA Destabilization in Drosophila and Its Translation Is Activated by the PAN GU Kinase by Tadros, Wael, Goldman, Aaron L., Babak, Tomas, Menzies, Fiona, Vardy, Leah, Orr-Weaver, Terry, Hughes, Timothy R., Westwood, J. Timothy, Smibert, Craig A., Lipshitz, Howard D.

“…In animals, egg activation triggers a cascade of posttranscriptional events that act on maternally synthesized RNAs. We show that, in Drosophila, the PAN GU…”
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Drosophila Cup is an eIF4E-binding protein that functions in Smaug-mediated translational repression by Nelson, Meryl R, Leidal, Andrew M, Smibert, Craig A

“…Translational regulation plays an essential role in development and often involves factors that interact with sequences in the 3′ untranslated region (UTR) of…”
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Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p by Sicheri, Frank, Aviv, Tzvi, Lin, Zhen, Ben-Ari, Giora, Smibert, Craig A

“…The SAM domain of the Saccharomyces cerevisiae post-transcriptional regulator Vts1p epitomizes a subfamily of SAM domains conserved from yeast to humans that…”
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Smaug Recruits the CCR4/POP2/NOT Deadenylase Complex to Trigger Maternal Transcript Localization in the Early Drosophila Embryo by Semotok, Jennifer L., Cooperstock, Ramona L., Pinder, Benjamin D., Vari, Heli K., Lipshitz, Howard D., Smibert, Craig A.

“…Background: Asymmetric localization of mRNAs within cells promotes precise spatio-temporal control of protein synthesis. Although cytoskeletal transport-based…”
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The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators by Sicheri, Frank, Smibert, Craig A, Aviv, Tzvi, Lin, Zhen, Lau, Stefanie, Rendl, Laura M

“…Anteroposterior patterning in Drosophila melanogaster is dependent on the sequence-specific RNA-binding protein Smaug, which binds to and regulates the…”
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Mechanisms of translational regulation in Drosophila by Wilhelm, James E., Smibert, Craig A.

“…Translational regulation plays an essential role in many phases of the Drosophila life cycle. During embryogenesis, specification of the developing body…”
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Differential regulation of endogenous and transduced β-globin genes during infection of erythroid cells with a herpes simplex virys type 10 recombinant by SMIBERT, C. A, SMILEY, J. R

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