Search Results - "SMET, Anouk"

Reverse engineering synthetic antiviral amyloids by Michiels, Emiel, Roose, Kenny, Gallardo, Rodrigo, Khodaparast, Ladan, Khodaparast, Laleh, van der Kant, Rob, Siemons, Maxime, Houben, Bert, Ramakers, Meine, Wilkinson, Hannah, Guerreiro, Patricia, Louros, Nikolaos, Kaptein, Suzanne J. F., Ibañez, Lorena Itatí, Smet, Anouk, Baatsen, Pieter, Liu, Shu, Vorberg, Ina, Bormans, Guy, Neyts, Johan, Saelens, Xavier, Rousseau, Frederic, Schymkowitz, Joost

“…Human amyloids have been shown to interact with viruses and interfere with viral replication. Based on this observation, we employed a synthetic biology…”
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Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection by El Bakkouri, Karim, Descamps, Francis, De Filette, Marina, Smet, Anouk, Festjens, Els, Birkett, Ashley, Van Rooijen, Nico, Verbeek, Sjef, Fiers, Walter, Saelens, Xavier

“…The ectodomain of matrix protein 2 (M2e) of influenza A virus is an attractive target for a universal influenza A vaccine: the M2e sequence is highly conserved…”
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The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017 by Catani, João Paulo Portela, Smet, Anouk, Ysenbaert, Tine, Vuylsteke, Marnik, Bottu, Guy, Mathys, Janick, Botzki, Alexander, Cortes-Garcia, Guadalupe, Strugnell, Tod, Gomila, Raul, Hamberger, John, Catalan, John, Ustyugova, Irina V, Farrell, Timothy, Stegalkina, Svetlana, Ray, Satyajit, LaRue, Lauren, Saelens, Xavier, Vogel, Thorsten U

“…Human H3N2 influenza viruses are subject to rapid antigenic evolution which translates into frequent updates of the composition of seasonal influenza vaccines…”
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Anti-neuraminidase and anti-hemagglutinin immune serum can confer inter-lineage cross protection against recent influenza B by Portela Catani, João Paulo, Ysenbaert, Tine, Smet, Anouk, Vuylsteke, Marnik, Vogel, Thorsten U, Saelens, Xavier

“…Influenza B viruses (IBV) are responsible for a considerable part of the burden caused by influenza virus infections. Since their emergence in the 1980s, the…”
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Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells by Smet, Anouk, Catani, Joao Paulo Portela, Ysenbaert, Tine, Gonçalves, Amanda, Kleanthous, Harry, Vogel, Thorsten U, Saelens, Xavier, Job, Emma R

“…Influenza neuraminidase (NA) is implicated in various aspects of the virus replication cycle and therefore is an attractive target for vaccination and…”
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Author Correction: Reverse engineering synthetic antiviral amyloids by Michiels, Emiel, Roose, Kenny, Gallardo, Rodrigo, Khodaparast, Ladan, Khodaparast, Laleh, van der Kant, Rob, Siemons, Maxime, Houben, Bert, Ramakers, Meine, Wilkinson, Hannah, Guerreiro, Patricia, Louros, Nikolaos, Kaptein, Suzanne J. F., Ibañez, Lorena Itatí, Smet, Anouk, Baatsen, Pieter, Liu, Shu, Vorberg, Ina, Bormans, Guy, Neyts, Johan, Saelens, Xavier, Rousseau, Frederic, Schymkowitz, Joost

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Single-domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge by Cardoso, Francisco Miguel, Ibañez, Lorena Itatí, Van den Hoecke, Silvie, De Baets, Sarah, Smet, Anouk, Roose, Kenny, Schepens, Bert, Descamps, Francis J, Fiers, Walter, Muyldermans, Serge, Depicker, Ann, Saelens, Xavier

“…Influenza virus neuraminidase (NA) is an interesting target of small-molecule antiviral drugs. We isolated a set of H5N1 NA-specific single-domain antibodies…”
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Pre-existing antibodies directed against a tetramerizing domain enhance the immune response against artificially stabilized soluble tetrameric influenza neuraminidase by Catani, João Paulo Portela, Job, Emma R., Ysenbaert, Tine, Smet, Anouk, Ray, Satyajit, LaRue, Lauren, Stegalkina, Svetlana, Barro, Mario, Vogel, Thorsten U., Saelens, Xavier

“…The neuraminidase (NA) is an abundant antigen at the surface of influenza virions. Recent studies have highlighted the immune-protective potential of NA…”
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Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies by De Filette, Marina, Martens, Wouter, Smet, Anouk, Schotsaert, Michael, Birkett, Ashley, Londoño-Arcila, Patricia, Fiers, Walter, Saelens, Xavier

“…Abstract The extracellular domain of influenza A virus matrix protein 2 (M2e) is strongly conserved. Therefore, vaccines based on M2e can induce broad-spectrum…”
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A GFP expressing influenza A virus to report in vivo tropism and protection by a matrix protein 2 ectodomain-specific monoclonal antibody by De Baets, Sarah, Verhelst, Judith, Van den Hoecke, Silvie, Smet, Anouk, Schotsaert, Michael, Job, Emma R, Roose, Kenny, Schepens, Bert, Fiers, Walter, Saelens, Xavier

“…The severity of influenza-related illness is mediated by many factors, including in vivo cell tropism, timing and magnitude of the immune response, and…”
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The role of TP53 in Cervical carcinogenesis by Tommasino, Massimo, Accardi, Rosita, Caldeira, Sandra, Dong, Wen, Malanchi, Ilaria, Smet, Anouk, Zehbe, Ingeborg

“…Functional loss of the tumor suppressor p53 by alterations in its TP53 gene is a frequent event in cancers of different anatomical regions. Cervical cancer is…”
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Human Papillomavirus Type 16 E6 Promotes Retinoblastoma Protein Phosphorylation and Cell Cycle Progression by MALANCHI, Ilaria, ACCARDI, Rosita, DIEHL, Frank, SMET, Anouk, ANDROPHY, Elliot, HOHEISEL, Jörg, TOMMASINO, Massimo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies by Van den Hoecke, Silvie, Ehrhardt, Katrin, Kolpe, Annasaheb, El Bakkouri, Karim, Deng, Lei, Grootaert, Hendrik, Schoonooghe, Steve, Smet, Anouk, Bentahir, Mostafa, Roose, Kenny, Schotsaert, Michael, Schepens, Bert, Callewaert, Nico, Nimmerjahn, Falk, Staeheli, Peter, Hengel, Hartmut, Saelens, Xavier

“…The ectodomain of matrix protein 2 is a universal influenza A virus vaccine candidate that provides protection through antibody-dependent effector mechanisms…”
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Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies by Schotsaert, Michael, Ysenbaert, Tine, Smet, Anouk, Schepens, Bert, Vanderschaeghe, Dieter, Stegalkina, Svetlana, Vogel, Thorsten U., Callewaert, Nico, Fiers, Walter, Saelens, Xavier

“…There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here,…”
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The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017 by Catani, João Paulo Portela, Smet, Anouk, Ysenbaert, Tine, Vuylsteke, Marnik, Bottu, Guy, Mathys, Janick, Botzki, Alexander, Cortes-Garcia, Guadalupe, Strugnell, Tod, Gomila, Raul, Hamberger, John, Catalan, John, Ustyugova, Irina V, Farrell, Timothy, Stegalkina, Svetlana, Ray, Satyajit, LaRue, Lauren, Saelens, Xavier, Vogel, Thorsten U

“…Human H3N2 influenza viruses are subject to rapid antigenic evolution which translates into frequent updates of the composition of seasonal influenza vaccines…”
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Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection by Pendzialek, Jochen, Roose, Kenny, Smet, Anouk, Schepens, Bert, Kufer, Peter, Raum, Tobias, Baeuerle, Patrick A., Muenz, Markus, Saelens, Xavier, Fiers, Walter

“…The ectodomain of the influenza A matrix protein 2 (M2e) is highly conserved amongst all influenza virus A subtypes. M2e is present on the surface of influenza…”
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Infection-permissive immunity provided by NA- and M2e-based vaccines protects against influenza A virus challenge and allows the induction of heterosubtypic immunity during subsequent infections. (VAC5P.1127) by Schotsaert, Michael, Ysenbaert, Tine, Smet, Anouk, Schepens, Bert, Fiers, Walter, Saelens, Xavier

“…Abstract Licensed influenza vaccines protect by inducing neutralizing antibodies against the main viral surface antigens hemagglutinin (HA) and neuraminidase…”
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Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells by Anouk Smet, Joao Paulo Portela Catani, Tine Ysenbaert, Amanda Gonçalves, Harry Kleanthous, Thorsten U. Vogel, Xavier Saelens, Emma R. Job

“…Influenza neuraminidase (NA) is implicated in various aspects of the virus replication cycle and therefore is an attractive target for vaccination and…”
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Skin human papillomavirus type 38 alters p53 functions by accumulation of ΔNp73 by Accardi, Rosita, Dong, Wen, Smet, Anouk, Cui, Rutao, Hautefeuille, Agnes, Gabet, Anne-Sophie, Sylla, Bakary S, Gissmann, Lutz, Hainaut, Pierre, Tommasino, Massimo

“…The E6 and E7 of the cutaneous human papillomavirus (HPV) type 38 immortalize primary human keratinocytes, an event normally associated with the inactivation…”
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TP53 mutations in squamous-cell carcinomas of the conjunctiva: evidence for UV-induced mutagenesis by Ateenyi-Agaba, Charles, Dai, Min, Le Calvez, Florence, Katongole-Mbidde, Edward, Smet, Anouk, Tommasino, Massimo, Franceschi, Silvia, Hainaut, Pierre, Weiderpass, Elisabete

“…Squamous cell carcinoma of the conjunctiva is associated with sun exposure and often occurs in HIV-positive individuals. We have analysed TP53 mutations in 21…”
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