Search Results - "SMALLEY, R. V"

Allopurinol: Intravenous Use for Prevention and Treatment of Hyperuricemia by SMALLEY, R. V, GUASPARI, A, HAASE-STATZ, S, ANDERSON, S. A, CEDERBERG, D, HOHNEKER, J. A

“…To tabulate data obtained over a 21-year period to determine the efficacy and safety of an intravenous (IV) allopurinol preparation. IV allopurinol was…”
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Final analysis of the ECOG I-COPA trial (E6484) in patients with non-Hodgkin's lymphoma treated with interferon alfa (IFN-α2a) plus an anthracycline-based induction regimen by SMALLEY, R. V, WELLER, E, HAWKINS, M. J, OKEN, M. M, O'CONNELL, M. J, HAASE-STATZ, S, BORDEN, E. C

“…The Eastern Cooperative Oncology Group (ECOG) performed a prospectively randomized study (E6484) evaluating the use of interferon alfa 2a (IFN-alpha2a) in…”
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Interferon Alfa Combined with Cytotoxic Chemotherapy for Patients with Non-Hodgkin's Lymphoma by Smalley, Richard V, Andersen, Janet W, Hawkins, Michael J, Bhide, Vandana, O'Connell, Michael J, Oken, Martin M, Borden, Ernest C

“…INTERFERON ALFA has been found to be an effective therapeutic agent in patients with low-grade non-Hodgkin's lymphoma. Early studies using both crude natural…”
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Intraperitoneal administration of interferon-gamma to carcinoma patients enhances expression of tumor-associated glycoprotein-72 and carcinoembryonic antigen on malignant ascites cells by Greiner, J W, Guadagni, F, Goldstein, D, Smalley, R V, Borden, E C, Simpson, J F, Molinolo, A, Schlom, J

“…The study was designed to determine whether in vivo interferon gamma (IFN-gamma) administration could enhance tumor antigen expression on the surface of human…”
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Human biologic response modification by interferon in the absence of measurable serum concentrations: a comparative trial of subcutaneous and intravenous interferon-beta serine by Goldstein, D, Sielaff, K M, Storer, B E, Brown, R R, Datta, S P, Witt, P L, Teitelbaum, A P, Smalley, R V, Borden, E C

“…The effect on a range of biologic responses of interferon-beta serine (IFN-beta ser), administered by either the sc or the iv route, was examined in 16…”
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Chemotherapy in advanced ovarian cancer: four systematic meta-analyses of individual patient data from 37 randomized trials by Aabo, K, Adams, M, Adnitt, P, Alberts, DS, Athanazziou, A, Barley, V, Bell, DR, Bianchi, U, Bolis, G, Brady, MF, Brodovsky, HS, Bruckner, H, Buyse, M, Canetta, R, Chylak, V, Cohen, CJ, Colombo, N, Conte, PF, Crowther, D, Edmonson, JH, Gennatas, C, Gilbey, E, Gore, M, Guthrie, D, Kaye, SB, Laing, AH, Landoni, F, Leonard, RC, Lewis, C, Liu, PY, Mangioni, C, Marsoni, S, Meerpohl, H, Omura, GA, Parmar, MKB, Pater, J, Pecorelli, S, Presti, M, Sauerbrei, W, Skarlos, DV, Smalley, RV, Solomon, HJ, Stewart, LA, Sturgeon, JFG, Tattersall, MHN, Wharton, JT, ten Bokkel Huinink, WW, Tomirotti, M, Torri, W, Trope, C, Turbow, MM, Vermorken, JB, Webb, MJ, Wilbur, DW, Williams, CJ, Wiltshaw, E, Yeap, BY

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Hyperthermic perfusion with chemotherapy for melanoma of the extremities by Ghussen, Farid, Krüger, Ingo, Smalley, Richard V., Groth, Wolfgang

“…A prospective randomized study was carried out to evaluate the effectiveness of additional regional cytostatic perfusion of the extremities in patients with…”
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Splenectomy vs. alpha interferon: a randomized study in patients with previously untreated hairy cell leukemia by Smalley, R V, Connors, J, Tuttle, R L, Anderson, S, Robinson, W, Whisnant, J K

“…Twenty patients with previously untreated hairy cell leukemia were randomized to undergo either splenectomy or to receive interferon alfa-N1, a highly purified…”
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Combination versus sequential single agent chemotherapy in advanced breast cancer: associations with metastatic sites and long-term survival by CHLEBOWSKI, R. T, SMALLEY, R. V, WEINER, J. M, IRWIN, L. E, BARTOLUCCI, A. A, BATEMAN, J. R

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A comparison of cyclophosphamide, adriamycin, 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone (CMFVP) in patients with metastatic breast cancer: a Southeastern Cancer Study Group project by Smalley, R V, Carpenter, J, Bartolucci, A, Vogel, C, Krauss, S

“…In an ongoing prospective randomized study, 113 evaluable patients have received either a three-drug combination that included cyclophosphamide, Adriamycin and…”
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Randomized trial of cyclophosphamide, doxorubicin, and 5-fluorouracil alone or alternating with a "cycle active" non-cross-resistant combination in women with visceral metastatic breast cancer: a Southeastern Cancer Study Group project by Vogel, C L, Smalley, R V, Raney, M, Krauss, S, Carpenter, J, Velez-Garcia, E, Fishkin, E, Raab, S, Moore, M R, Stagg, M

“…Patients with visceral patterns of metastatic breast cancer were stratified according to dominant metastatic site and performance status and then randomized to…”
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Oral piritrexim : a phase II study in patients with advanced soft tissue sarcoma by SCHIESEL, J. D, CARABASI, M, MAGILL, G, CASPER, E, CHENG, E, MARKS, L, FEYZI, J, CLENDENINN, N. J, SMALLEY, R. V

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A phase II study of crisnatol mesylate in patients with ovarian carcinoma by SMALLEY, R. V, GOLDSTEIN, D, BULKOWSKI, D, HANNON, C, BUCHLER, D, KNUDSEN, C, TUTTLE, R. L

“…Fourteen patients with advanced ovarian cancer received a 72 hour infusion of a new DNA intercalator, crisnatol mesylate, administered intravenously. There was…”
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Applications of monoclonal antibodies and recombinant cytokines for the treatment of human colorectal and other carcinomas by Greiner, J W, Smalley, R V, Borden, E C, Martin, E W, Guadagni, F, Roselli, M, Schlom, J

“…Monoclonal antibodies (MAbs) which recognize a human tumor antigen, termed tumor-associated glycoprotein-72 (TAG-72), have successfully been used to localize…”
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A phase II evaluation of a 3-drug combination of cyclophosphamide, doxorubicin and 5-fluorouracil and of 5-fluorouracil in patients with advanced bladder carcinoma or stage D prostatic carcinoma by Smalley, R V, Bartolucci, A A, Hemstreet, G, Hester, M

“…The Southeastern Cancer Study Group has evaluated 5-fluorouracil administered intravenously weekly at a dosage of 600 mg. per M.2 as a single agent, and the…”
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Terminal Deoxynucleotidyl Transferase (TdT), Cytochemistry, and Membrane Receptors in Adult Acute Leukemia by Gordon, David S., Hutton, John J., Smalley, Richard V., Meyer, Leo M., Vogler, W. Ralph

“…Terminal deoxynucleotidyl transferase activity, immunologic membrane markers, and cytochemical reactivity were examined in blasts of 80 adults with acute…”
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Role of interferon-alfa in NHL: still controversial? by Haase-Statz, S, Smalley, R V

“…Recombinant interferon-alfa (Intron A, Roferon-A) has been under investigation as a therapeutic agent for non-Hodgkin's lymphoma (NHL) for 25 years. It has…”
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Preoperative scanning: evaluation for metastatic disease in carcinoma of the breast, lung, colon, bladder, and prostate by Smalley, R V, Malmud, L S, Ritchie, W G

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Clinical and biological effects of recombinant interferon-beta administered intravenously daily in phase I trial by Borden, E C, Hawkins, M J, Sielaff, K M, Storer, B M, Schiesel, J D, Smalley, R V

“…Interferon-beta serine (IFN-beta ser) was administered intravenously (i.v.) daily for 14 days at doses of 3, 10, 30 X 10(6) units to 19 patients. In this Phase…”
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Advanced breast cancer with bone-only metastases: a chemotherapeutically responsive pattern of metastases by Smalley, R V, Scogna, D M, Malmud, L S

“…Twenty-one patients, presenting with metastases only to bone from a primary adenocarcinoma of the breast having previously undergone mastectomy, tolerated…”
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