Search Results - "SLOAND, E. M"

Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia by Calado, R T, Cooper, J N, Padilla-Nash, H M, Sloand, E M, Wu, C O, Scheinberg, P, Ried, T, Young, N S

“…In cell and animal models, telomere erosion promotes chromosomal instability via breakage-fusion-bridge cycles, contributing to the early stages of…”
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Altered naive and memory CD4+ T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome by Zou, J X, Rollison, D E, Boulware, D, Chen, D-T, Sloand, E M, Pfannes, L V, Goronzy, J J, Bai, F, Painter, J S, Wei, S, Cosgrove, D, List, A F, Epling-Burnette, P K

“…Response to immunosuppressive therapy (IST) in younger patients with myelodysplastic syndrome (MDS) has been linked to a T-cell-dominant autoimmune process…”
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Hematopoietic stem cells and progenitors of chronic myeloid leukemia express leukemia-associated antigens: implications for the graft-versus-leukemia effect and peptide vaccine-based immunotherapy by Yong, A S M, Keyvanfar, K, Eniafe, R, Savani, B N, Rezvani, K, Sloand, E M, Goldman, J M, Barrett, A J

“…The cure of chronic myeloid leukemia (CML) patients following allogeneic stem cell transplantation (SCT) is attributed to graft-versus-leukemia (GVL) effects…”
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Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients by RISITANO, A. M, MACIEJEWSKI, J. P, MURANSKI, P, WLODARSKI, M, O'KEEFE, C, SLOAND, E. M, YOUNG, N. S

“…In paroxysmal nocturnal hemoglobinuria (PNH), clonal expansion of glycosylphosphatidylinositol-anchored proteins (GPI-AP)-deficient cells leads to a syndrome…”
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Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome : Effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication by SLOAND, E. M, YOUNG, N. S, KUMAR, P, WEICHOLD, F. F, SATO, T, MACIEJEWSKI, J. P

“…Direct killing of CD4+ lymphocytes by human immunodeficiency virus-1 (HIV-1) probably cannot account for the magnitude of the loss of these cells during the…”
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Human Immunodeficiency Virus Type 1 Protease Inhibitor Modulates Activation of Peripheral Blood CD4+ T Cells and Decreases Their Susceptibility to Apoptosis In Vitro and In Vivo by Sloand, Elaine M., Kumar, Princy N., Kim, Sonnie, Chaudhuri, Aniruddho, Weichold, Frank F., Young, Neal S.

“…CD4+ T cells from patients with human immunodeficiency virus (HIV) infection undergo apoptosis at an increased rate, which leads to their depletion during…”
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Comparison of random-donor platelet concentrates prepared from whole blood units and platelets prepared from single-donor apheresis collections by Sloand, E M, Yu, M, Klein, H G

“…The use of fresh platelets results in better posttransfusion recovery and survival than does the use of platelets that have been stored before transfusion…”
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Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone by MACIEJEWSKI, J. P, SLOAND, E. M, SATO, T, ANDERSON, S, YOUNG, N. S

“…Paroxysmal nocturnal hemoglobinuria (PNH) results from somatic mutations in the PIG-A gene, leading to poor presentation of glycosylphosphatidylinositol…”
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Studies on platelet membrane glycoproteins and platelet function during hemodialysis by SLOAND, J. A, SLOAND, E. M

“…Hemodialysis only partially corrects the defects in platelet function associated with uremia. Platelet contact with the artificial surfaces of the dialysis…”
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Effect of white cells on platelets during storage by Sloand, E M, Klein, H G

“…White cells (WBCs) present in stored platelet concentrates have adverse effects on platelet function and on posttransfusion recovery. Although these effects…”
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Use of Human Immunodeficiency Virus (HIV) Human Hyperimmune Immunoglobulin in HIV Type 1-Infected Children (Pediatric AIDS Clinical Trials Group Protocol 273) by Stiehm, E. Richard, Fletcher, Courtney V., Mofenson, Lynne M., Palumbo, Paul E., Kang, Minhee, Fenton, Terry, Sapan, Christine V., Meyer, William A., Shearer, William T., Hawkins, Elizabeth, Fowler, Mary Glenn, Bouquin, Pamela, Purdue, Lynette, Sloand, Elaine M., Nemo, George J., Wara, Diane, Bryson, Yvonne J., Starr, Stuart E., Petru, Ann, Burchett, Sandra

“…The clinical, immunologic, and virologic effects and the pharmacokinetics of human immunodeficiency virus (HIV) human hyperimmune immunoglobulin (HIVIG) were…”
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Viral Risks Associated with Blood Transfusion by Sloand, Elaine M.

“…Great strides have been made within the last decade to help ensure the safety of the blood supply. Additional tests to detect infectious agents, as well as…”
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Secondary colony formation after long-term bone marrow culture using peripheral blood and bone marrow of HIV-infected patients by SLOAND, E. M, YOUNG, N. S, SATO, T, KUMAR, P, KIM, S, WEICHOLD, F. F, MACIEJEWSKI, J. P

“…To determine if defective bone marrow function in HIV infection is associated with decreased numbers of progenitor cells or defective stromal cell function…”
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Reduction of platelet glycoprotein Ib in uraemia by Sloand, E M, Sloand, J A, Prodouz, K, Klein, H G, Yu, M W, Harvath, L, Fricke, W

“…Patients with uraemia have abnormal platelet function that may be partially corrected by haemodialysis, cryoprecipitate or 1-desamino-8-D-arginine vasopressin…”
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Epidemiology of thrombocytopenia in HIV infection by Sloand, E M, Klein, H G, Banks, S M, Vareldzis, B, Merritt, S, Pierce, P

“…Thrombocytopenia is a known complication of human immunodeficiency virus Type-1 (HIV-1) infection, and more data need to be collected on its frequency,…”
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Effect of amphotericin B and fluconazole on platelet membrane glycoproteins by Sloand, E M, Kumar, P, Yu, M, Klein, H G

“…Fever, chills, and reduced platelet recovery may result when platelets are transfused simultaneously with amphotericin B. Amphotericin B reportedly increases…”
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1-Deamino-8-D-arginine vasopressin (DDAVP) increases platelet membrane expression of glycoprotein Ib in patients with disorders of platelet function and after cardiopulmonary bypass by Sloand, E M, Alyono, D, Klein, H G, Chang, P, Yu, M, Lightfoot, F G, Kessler, C

“…1-deamino-8-D-Arginine vasopressin (DDAVP) shortens the bleeding time in some patients with platelet dysfunction and decreases blood loss in some…”
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Effect of Albumin on the Inhibition of Platelet Aggregation by β-Lactam Antibiotics by Sloand, E.M., Klein, H.G., Pastakia, K.B., Pierce, P., Prodouz, K.N.

“…Platelet aggregation and bleeding time abnormalities are reported in patients receiving p-lactam antibiotics (pLAs), although clinical bleeding most frequently…”
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Protease inhibitors stimulate hematopoiesis and decrease apoptosis and ICE expression in CD34+ cells by Sloand, Elaine M., Maciejewski, Jaroslaw, Kumar, Princy, Kim, Sonnie, Chaudhuri, Aniruddho, Young, Neal

“…Highly active retroviral therapy has been associated with a decline in the frequency of cytopenia in patients with human immunodeficiency virus (HIV)…”
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Preparation of IgA-deficient platelets by Sloand, E M, Fox, S M, Banks, S M, Klein, H G

“…The IgA-deficient patient presents a difficult transfusion problem, particularly if he or she has previously been immunized and has formed IgA antibodies…”
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