Search Results - "SLOAN, Derek J"

STrengthening the Reporting Of Pharmacogenetic Studies: Development of the STROPS guideline by Chaplin, Marty, Kirkham, Jamie J., Dwan, Kerry, Sloan, Derek J., Davies, Geraint, Jorgensen, Andrea L.

“…[...]large sample sizes are typically required to detect pharmacogenetic associations. Marty Chaplin (researcher into meta-analysis of pharmacogenetic…”
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Unravelling patient pathways in the context of antibacterial resistance in East Africa by Keenan, Katherine, Fredricks, Kathryn J, Al Ahad, Mary Abed, Neema, Stella, Mwanga, Joseph R, Kesby, Mike, Mushi, Martha F, Aduda, Annette, Green, Dominique L, Lynch, Andy G, Huque, Sarah I, Mmbaga, Blandina T, Worthington, Hannah, Kansiime, Catherine, Olamijuwon, Emmanuel, Ntinginya, Nyanda E, Loza, Olga, Bazira, Joel, Maldonado-Barragán, Antonio, Smith, VAnne, Decano, Arun Gonzales, Njeru, John Mwaniki, Sandeman, Alison, Stelling, John, Elliott, Alison, Aanensen, David, Gillespie, Stephen H, Kibiki, Gibson, Sabiiti, Wilber, Sloan, Derek J, Asiimwe, Benon B, Kiiru, John, Mshana, Stephen E, Holden, Matthew T G

“…A key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals' use of antibiotics (ABs) to treat illness. To better…”
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Protocol for an interdisciplinary cross-sectional study investigating the social, biological and community-level drivers of antimicrobial resistance (AMR): Holistic Approach to Unravel Antibacterial Resistance in East Africa (HATUA) by Asiimwe, Benon B, Kiiru, John, Mshana, Stephen E, Neema, Stella, Keenan, Katherine, Kesby, Mike, Mwanga, Joseph R, Sloan, Derek J, Mmbaga, Blandina T, Smith, V Anne, Gillespie, Stephen H, Lynch, Andy G, Sandeman, Alison, Stelling, John, Elliott, Alison, Aanensen, David M, Kibiki, Gibson E, Sabiiti, Wilber, Holden, Matthew T G

“…IntroductionAntimicrobial resistance (AMR) is a global health threat that requires urgent research using a multidisciplinary approach. The biological drivers…”
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Pharmacokinetics, SAfety/tolerability, and EFficacy of high-dose RIFampicin in tuberculosis-HIV co-infected patients on efavirenz- or dolutegravir-based antiretroviral therapy: study protocol for an open-label, phase II clinical trial (SAEFRIF) by Nabisere, Ruth, Musaazi, Joseph, Denti, Paolo, Aber, Florence, Lamorde, Mohammed, Dooley, Kelly E, Aarnoutse, Rob, Sloan, Derek J, Sekaggya-Wiltshire, Christine

“…Tuberculosis (TB) is a significant public health problem that causes substantial morbidity and mortality. Current first-line anti-TB chemotherapy, although…”
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A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi by Rothe, Camilla, Sloan, Derek J, Goodson, Patrick, Chikafa, Jean, Mukaka, Mavuto, Denis, Brigitte, Harrison, Tom, van Oosterhout, Joep J, Heyderman, Robert S, Lalloo, David G, Allain, Theresa, Feasey, Nicholas A

“…Cryptococcal meningitis is the most common neurological infection in HIV infected patients in Sub Saharan Africa, where gold standard treatment with…”
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Evaluation of Xpert MTB/RIF for Detection of Tuberculosis from Blood Samples of HIV-Infected Adults Confirms Mycobacterium tuberculosis Bacteremia as an Indicator of Poor Prognosis by Feasey, Nicholas A, Banada, Padmapriya P, Howson, William, Sloan, Derek J, Mdolo, Aaron, Boehme, Catharina, Chipungu, Geoffrey A, Allain, Theresa J, Heyderman, Robert S, Corbett, Elizabeth L, Alland, David

“…OA  Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
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Detection and Quantification of Viable Mycobacterium tuberculosis Bacilli in Saline-Processed Stool Samples by Tuberculosis Molecular Bacterial Load Assay: a Potential Alternative for Processing Stool by Musisi, Emmanuel, Ssesolo, Abdul, Sloan, Derek J, Gillespie, Stephen H, Sabiiti, Wilber

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Antibiotic dispensing practices during COVID-19 and implications for antimicrobial resistance (AMR): parallel mystery client studies in Uganda and Tanzania by Olamijuwon, Emmanuel, Konje, Eveline, Kansiime, Catherine, Kesby, Mike, Keenan, Katherine, Neema, Stella, Asiimwe, Benon, Mshana, Stephen E, Mushi, Martha F, Loza, Olga, Sunday, Benjamin, Sandeman, Alison, Sloan, Derek J, Benitez-Paez, Fernando, Mwanga, Joseph R, Sabiiti, Wilber, Holden, Matthew T G

“…Over-the-counter antibiotic access is common in low-and-middle-income countries and this may accelerate antimicrobial resistance. Our study explores critical…”
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CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis by Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek J, Davies, Geraint, Jorgensen, Andrea L

“…Treatment with anti-tuberculosis drugs may cause patients to experience serious adverse effects. Genetic factors, such as polymorphisms of CYP genes, may…”
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“It is not easy”: Experiences of people living with HIV and tuberculosis on Tuberculosis treatment in Uganda by Nabisere-Arinaitwe, Ruth, Namatende-Sakwa, Lydia, Bayiga, Josephine, Nampala, Juliet, Alinaitwe, Lucy, Aber, Florence, Otaalo, Brian, Musaazi, Joseph, King, Rachel, Kesby, Mike, Sloan, Derek J., Sekaggya-Wiltshire, Christine

“…Completion of tuberculosis (TB) treatment presents several challenges to patients, including long treatment duration, medication adverse-effects and heavy pill…”
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Pan-Resistome Characterization of Uropathogenic Escherichia coli and Klebsiella pneumoniae Strains Circulating in Uganda and Kenya, Isolated from 2017-2018 by Decano, Arun Gonzales, Pettigrew, Kerry, Sabiiti, Wilber, Sloan, Derek J, Neema, Stella, Bazira, Joel, Kiiru, John, Onyango, Hellen, Asiimwe, Benon, Holden, Matthew T G

“…Urinary tract infection (UTI) develops after a pathogen adheres to the inner lining of the urinary tract. Cases of UTIs are predominantly caused by several…”
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Protocol for the development of the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline: checklist of items for reporting pharmacogenetic studies by Richardson, Marty, Kirkham, Jamie J, Dwan, Kerry M, Sloan, Derek J, Davies, Geraint, Jorgensen, Andrea

“…IntroductionLarge sample sizes are often required to detect statistically significant associations between pharmacogenetic markers and treatment response…”
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High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis by Musisi, Emmanuel, Sessolo, Abdul, Kaswabuli, Sylvia, Zawedde, Josephine, Byanyima, Patrick, Kasinga, Shariifah, Sanyu, Ingvar, Uwimaana, Esther, Walimbwa, Stanley, Olore, Joseph, Ssengooba, Willy, Sekaggya, Christine, Joloba, Moses L, Worodria, William, Huang, Laurence, Gillespie, Stephen H, Sloan, Derek J, Sabiiti, Wilber

“…Not all patients produce sputum, yet most available TB tests use sputum. We investigated the utility of a novel RNA-based quantitative test, the tuberculosis…”
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All nonadherence is equal but is some more equal than others? Tuberculosis in the digital era by Stagg, Helen R, Flook, Mary, Martinecz, Antal, Kielmann, Karina, Abel Zur Wiesch, Pia, Karat, Aaron S, Lipman, Marc C I, Sloan, Derek J, Walker, Elizabeth F, Fielding, Katherine L

“…Adherence to treatment for tuberculosis (TB) has been a concern for many decades, resulting in the World Health Organization's recommendation of the direct…”
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Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study by McCallum, Andrew D, Nyirenda, Deborah, Lora, Wezzie, Khoo, Saye H, Sloan, Derek J, Mwandumba, Henry C, Desmond, Nicola, Davies, Geraint R

“…Bronchoscopy is an established research tool in Malawi, enabling collection of pulmonary samples for immunological, pharmacological, and microbiological…”
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Accuracy and consequences of using trial-of-antibiotics for TB diagnosis (ACT-TB study): protocol for a randomised controlled clinical trial by Divala, Titus Henry, Fielding, Katherine L, Sloan, Derek J, French, Neil, Nliwasa, Marriott, MacPherson, Peter, Kandulu, Chikondi Charity, Chiume, Lingstone, Chilanga, Sanderson, Ndaferankhande, Masiye John, Corbett, Elizabeth L

“…IntroductionOver 40% of global tuberculosis case notifications are diagnosed clinically without mycobacteriological confirmation. Standard diagnostic…”
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Linezolid for drug-resistant pulmonary tuberculosis by Singh, Bhagteshwar, Cocker, Derek, Ryan, Hannah, Sloan, Derek J

“…Linezolid was recently re-classified as a Group A drug by the World Health Organization (WHO) for treatment of multi-drug resistant tuberculosis (MDR-TB) and…”
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TST positivity in household contacts of tuberculosis patients: a case-contact study in Malawi by Hector, Jonas, Anderson, Suzanne T, Banda, Gertrude, Kamdolozi, Mercy, Jefferys, Laura F, Shani, Doris, Garton, Natalie J, Mwale, Agnes, Jobe, Annie, Davies, Geraint R, Sloan, Derek J

“…Screening household contacts of active tuberculosis (TB) patients is recommended for TB control. Due to resource constraints this rarely occurs in lower income…”
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Treatment seeking behaviours, antibiotic use and relationships to multi-drug resistance: A study of urinary tract infection patients in Kenya, Tanzania and Uganda by Sado, Keina, Keenan, Katherine, Manataki, Areti, Kesby, Mike, Mushi, Martha F, Mshana, Stephen E, Mwanga, Joseph R, Neema, Stella, Asiimwe, Benon, Bazira, Joel, Kiiru, John, Green, Dominique L, Ke, Xuejia, Maldonado-Barragán, Antonio, Abed Al Ahad, Mary, Fredricks, Kathryn J, Gillespie, Stephen H, Sabiiti, Wilber, Mmbaga, Blandina T, Kibiki, Gibson, Aanensen, David, Smith, V Anne, Sandeman, Alison, Sloan, Derek J, Holden, Matthew T G

“…Antibacterial resistance (ABR) is a major public health threat. An important accelerating factor is treatment-seeking behaviour, including inappropriate…”
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Sensitivity and specificity of using trial-of-antibiotics versus sputum mycobacteriology for diagnosis of tuberculosis: protocol for a systematic literature review by Divala, Titus H, Fielding, Katherine L, Nliwasa, Marriott, Sloan, Derek J, Gupta-Wright, Ankur, Corbett, Elizabeth L

“…Suboptimal diagnostics for pulmonary tuberculosis (PTB) drives use of 'trial-of-antibiotics (non-tuberculosis)' in an attempt to distinguish PTB patients from…”
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