Search Results - "SLIZ, Piotr"

Collaboration gets the most out of software by Morin, Andrew, Eisenbraun, Ben, Key, Jason, Sanschagrin, Paul C, Timony, Michael A, Ottaviano, Michelle, Sliz, Piotr

“…By centralizing many of the tasks associated with the upkeep of scientific software, SBGrid allows researchers to spend more of their time on research…”
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Structural impact on SARS-CoV-2 spike protein by D614G substitution by Zhang, Jun, Cai, Yongfei, Xiao, Tianshu, Lu, Jianming, Peng, Hanqin, Sterling, Sarah M, Walsh, Jr, Richard M, Rits-Volloch, Sophia, Zhu, Haisun, Woosley, Alec N, Yang, Wei, Sliz, Piotr, Chen, Bing

“…Substitution for aspartic acid (D) by glycine (G) at position 614 in the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…”
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Regulating Protein-RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway by Oyejobi, Greater Kayode, Yan, Xiaodan, Sliz, Piotr, Wang, Longfei

“…Originally discovered in , LIN28 is an evolutionarily conserved zinc finger RNA-binding protein (RBP) that post-transcriptionally regulates genes involved in…”
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Single-cell transcriptome profile of mouse skin undergoing antigen-driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions by Leyva-Castillo, Juan Manuel, Sun, Liang, Wu, Shih-Ying, Rockowitz, Shira, Sliz, Piotr, Geha, Raif S.

“…Allergic skin inflammation elicited in mice by epicutaneous (EC) sensitization with antigen shares characteristics with human atopic dermatitis (AD). We…”
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Structural and functional impact by SARS-CoV-2 Omicron spike mutations by Zhang, Jun, Cai, Yongfei, Lavine, Christy L., Peng, Hanqin, Zhu, Haisun, Anand, Krishna, Tong, Pei, Gautam, Avneesh, Mayer, Megan L., Rits-Volloch, Sophia, Wang, Shaowei, Sliz, Piotr, Wesemann, Duane R., Yang, Wei, Seaman, Michael S., Lu, Jianming, Xiao, Tianshu, Chen, Bing

“…The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), bearing an unusually high number of mutations, has become a dominant…”
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A quick guide to software licensing for the scientist-programmer by Morin, Andrew, Urban, Jennifer, Sliz, Piotr

“…[...]proprietary licenses are often very restrictive for end-users. [...]in our software-dependent information age, few laws are influencing our professional…”
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Lipid-protein interactions in double-layered two-dimensional AQP0 crystals by Sliz, Piotr, Walz, Thomas, Cheng, Yifan, Gonen, Tamir, Fujiyoshi, Yoshinori, Hiroaki, Yoko, Harrison, Stephen C

“…Lens-specific aquaporin-0 (AQP0) functions as a specific water pore and forms the thin junctions between fibre cells. Here we describe a 1.9 A resolution…”
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Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine by Kim, Seokhee, Malinverni, Juliana C, Sliz, Piotr, Silhavy, Thomas J, Harrison, Stephen C, Kahne, Daniel

“…Integral β-barrel proteins are found in the outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria. The machine that assembles these…”
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Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4) by Thornton, James E, Du, Peng, Jing, Lili, Sjekloca, Ljiljana, Lin, Shuibin, Grossi, Elena, Sliz, Piotr, Zon, Leonard I, Gregory, Richard I

“…Recent small RNA sequencing data has uncovered 3' end modification of mature microRNAs (miRNAs). This non-templated nucleotide addition can impact miRNA gene…”
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Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28 by Piskounova, Elena, Viswanathan, Srinivas R., Janas, Maja, LaPierre, Robert J., Daley, George Q., Sliz, Piotr, Gregory, Richard I.

“…The developmentally regulated RNA-binding protein Lin28 blocks processing of let-7 family microRNAs (miRNAs) in embryonic cells. The molecular basis for this…”
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Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase by Huang, Fengtao, Lu, Xueling, Yu, Chunxiao, Sliz, Piotr, Wang, Longfei, Zhu, Bin

“…PrimPols are a class of primases that belong to the archaeo-eukaryotic primase (AEP) superfamily but have both primase and DNA polymerase activities…”
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LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation by Wang, Longfei, Nam, Yunsun, Lee, Anna K., Yu, Chunxiao, Roth, Kira, Chen, Casandra, Ransey, Elizabeth M., Sliz, Piotr

“…LIN28 is an RNA binding protein that plays crucial roles in pluripotency, glucose metabolism, tissue regeneration, and tumorigenesis. LIN28 binds to the let-7…”
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Corrigendum: Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase by Huang, Fengtao, Lu, Xueling, Yu, Chunxiao, Sliz, Piotr, Wang, Longfei, Zhu, Bin

“…[This corrects the article DOI: 10.3389/fmicb.2021.766612.]…”
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Structural Basis for Cooperativity in Recruitment of MAML Coactivators to Notch Transcription Complexes by Nam, Yunsun, Sliz, Piotr, Song, Luyan, Aster, Jon C., Blacklow, Stephen C.

“…Notch receptors transduce essential developmental signals between neighboring cells by forming a complex that leads to transcription of target genes upon…”
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Protein structure determination by exhaustive search of Protein Data Bank derived databases by Stokes-Rees, Ian, Sliz, Piotr, Brunger, Axel T.

“…Parallel sequence and structure alignment tools have become ubiquitous and invaluable at all levels in the study of biological systems. We demonstrate the…”
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Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis by Yuan, Yanqiu, Barrett, Dianah, Zhang, Yi, Kahne, Daniel, Sliz, Piotr, Walker, Suzanne

“…Peptidoglycan is an essential polymer that forms a protective shell around bacterial cell membranes. Peptidoglycan biosynthesis is the target of many…”
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Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription by Nam, Yunsun, Sliz, Piotr, Pear, Warren S, Aster, Jon C, Blacklow, Stephen C

“…Notch receptors control differentiation and contribute to pathologic states such as cancer by interacting directly with a transcription factor called CSL (for…”
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Virtual Screening for Ligand Discovery at the σ1 Receptor by Greenfield, Daniel A, Schmidt, Hayden R, Skiba, Meredith A, Mandler, Michael D, Anderson, Jacob R, Sliz, Piotr, Kruse, Andrew C

“…The σ1 receptor is a transmembrane protein implicated in several pathophysiological conditions, including neurodegenerative disease ( J. Pharmacol. Sci. 2015…”
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Children’s rare disease cohorts: an integrative research and clinical genomics initiative by Rockowitz, Shira, LeCompte, Nicholas, Carmack, Mary, Quitadamo, Andrew, Wang, Lily, Park, Meredith, Knight, Devon, Sexton, Emma, Smith, Lacey, Sheidley, Beth, Field, Michael, Holm, Ingrid A., Brownstein, Catherine A., Agrawal, Pankaj B., Kornetsky, Susan, Poduri, Annapurna, Snapper, Scott B., Beggs, Alan H., Yu, Timothy W., Williams, David A., Sliz, Piotr

“…While genomic data is frequently collected under distinct research protocols and disparate clinical and research regimes, there is a benefit in streamlining…”
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Long-Term Characteristics of Human-Derived Biliary Organoids under a Single Continuous Culture Condition by Aktas, Ranan G, Karski, Michael, Issac, Biju, Sun, Liang, Rockowitz, Shira, Sliz, Piotr, Vakili, Khashayar

“…Organoids have been used to investigate the three-dimensional (3D) organization and function of their respective organs. These self-organizing 3D structures…”
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