Search Results - "SLILATY, Steve N"

Adva-27a, a Novel Podophyllotoxin Derivative Found to Be Effective against Multidrug Resistant Human Cancer Cells by MERZOUKI, Abderrazzak, BUSCHMANN, Michael D, JEAN, Myriam, YOUNG, Rebecca S, LIAO, S. I, GAL, Susannah, LI, Zuomei, SLILATY, Steve N

“…Multidrug resistance poses a serious challenge in cancer therapy. To address this problem, we designed and synthesized Adva-27a, a novel non-ester…”
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Abstract 1758: A podophyllotoxin derivative, Adva-27a, is more potent at killing multi-drug resistant breast cancer cells than etoposide by Young, Rebecca S., Liao, Si, Slilaty, Steve N., Gal, Susannah

“…A novel non-ester GEM-difluorinated C-glycoside derivative of podophyllotoxin, Adva-27a, had been designed and synthesized. The growth inhibitory properties of…”
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Intramolecular cleavage of lexA and phage .lambda. repressors: dependence of kinetics on repressor concentration, pH, temperature, and solvent by Slilaty, Steve N, Rupley, John A, Little, John W

“…LexA repressor of Escherichia coli and phage lambda repressor are inactivated in vivo and in vitro by specific cleavage of an Ala-Gly peptide bond in reactions…”
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Gene Transfer by Polyoma-Like Particles Assembled in a Cell-Free System by Slilaty, Steve N., Aposhian, H. Vasken

“…Empty capsids of polyoma virus interact with DNA in a cell-free system to form polyoma-like particles (PLP). The DNA in these particles is protected from the…”
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Accurate insertional inactivation of lacZα: construction of pTrueBlue and M13TrueBlue cloning vectors by N. Slilaty, Steve, Lebel, Suzanne

“…Color selection plasmid and phage vectors based on insertional inactivation of the lacZα gene fragment have been in wide use for nearly two decades. The…”
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Lysine-156 and Serine-119 are Required for LexA Repressor Cleavage: A Possible Mechanism by Slilaty, Steve N., Little, John W.

“…LexA repressor of Escherichia coli is inactivated in vivo by a specific cleavage reaction requiring activated RecA protein. In vitro, cleavage requires…”
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Primary sequence of the glucanase gene from Oerskovia xanthineolytica. Expression and purification of the enzyme from Escherichia coli by Shen, S H, Chrétien, P, Bastien, L, Slilaty, S N

“…A 2.7-kilobase fragment of DNA from Oerskovia xanthineolytica containing the gene for a beta-1,3-glucanase has been isolated and its complete nucleotide…”
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Cleavage of LexA repressor by Little, J W, Kim, B, Roland, K L, Smith, M H, Lin, L L, Slilaty, S N

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Synthesis and secretion of hepatitis B middle surface antigen by the methylotrophic yeast Hansenula polymorpha by Shen, S H, Bastien, L, Nguyen, T, Fung, M, Slilaty, S N

“…The methylotrophic yeast, Hansenula polymorpha, has been developed as a host system for the synthesis of heterologous proteins. The middle surface antigen of…”
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The role of electrostatic interactions in the mechanism of peptide bond hydrolysis by a Ser-Lys catalytic dyad by Slilaty, S N, Vu, H K

“…General-base catalysis in the active site of serine proteases is carried out by the imidazole side chain of a histidine. During formation of the transition…”
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A NOVEL GENE TRANSFER SYSTEM FOR MAMMALIAN CELLS by SLILATY, STEVE N

“…Productive infection of mouse cells with polyoma virus yields mainly two types of particles: Complete virions and empty capsids. Empty polyoma capsids have…”
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Independent folding of individual components in hybrid proteins by SLILATY, Steve N., OUELLET, Mariette, FUNG, Margaret, SHEN, Shi‐Hsiang

“…Inactivation of the Escherichia coli repressor protein, LexA, takes place through a cleavage reaction which hydrolyzes the Ala84‐Gly85 peptide bond near the…”
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Site-directed mutagenesis by complementary-strand synthesis using a closing oligonucleotide and double-stranded DNA templates by Slilaty, S N, Fung, M, Shen, S H, Lebel, S

“…An approach for generating structures capable of directing full-length complementary-strand synthesis for double-stranded plasmid DNA is described. The…”
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Independent folding of individual components in hybrid proteins : evidence that the carboxy-terminal 135 residues of the LexA repressor constitute a single autonomous domain by SLILATY, S. N, OUELLET, M, FUNG, M, SHI-HSIANG SHEN

“…Inactivation of the Escherichia coli repressor protein, LexA, takes place through a cleavage reaction which hydrolyzes the Ala84-Gly85 peptide bond near the…”
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