Search Results - "SLATER, Emily P"
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The Immune Microenvironment in Pancreatic Cancer
Published in International journal of molecular sciences (01-10-2020)“…The biology of solid tumors is strongly determined by the interactions of cancer cells with their surrounding microenvironment. In this regard, pancreatic…”
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Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers
Published in Journal of clinical oncology (10-06-2016)“…Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. Hereditary factors play a role in the development of PDAC in 3% to 5% of all patients…”
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3
Proteomics biomarker discovery for individualized prevention of familial pancreatic cancer using statistical learning
Published in PloS one (26-01-2023)“…The low five-year survival rate of pancreatic ductal adenocarcinoma (PDAC) and the low diagnostic rate of early-stage PDAC via imaging highlight the need to…”
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4
ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9
Published in International journal of molecular sciences (10-02-2022)“…The metalloprotease-disintegrin ADAM8 is critically involved in the progression of pancreatic cancer. Under malignant conditions, ADAM8 is highly expressed and…”
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5
Characteristics of familial pancreatic cancer families with additional colorectal carcinoma
Published in Familial cancer (01-07-2023)“…Familial pancreatic cancer (FPC) is a rare hereditary tumor entity with broad phenotypic heterogeneity, including colorectal carcinoma (CRC) in some families…”
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Increased Myocardial MAO-A, Atrogin-1, and IL-1β Expression in Transgenic Mice with Pancreatic Carcinoma-Benefit of MAO-A Inhibition for Cardiac Cachexia
Published in Biomedicines (03-09-2024)“…Cancer cachexia (CC) continues to challenge clinicians by massively impairing patients' prognosis, mobility, and quality of life through skeletal muscle…”
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German national case collection for familial pancreatic cancer (FaPaCa): ten years experience
Published in Familial cancer (01-06-2011)“…Familial pancreatic cancer (FPC) is a rare hereditary tumor syndrome. The 10-years experience of the national case collection for familial pancreatic cancer of…”
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8
Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer
Published in Oncotarget (17-05-2016)“…Autophagy is a homeostatic, catabolic degradation process and cell fate essential regulatory mechanism. Protracted autophagy triggers cell death; its aberrant…”
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Effects of Monoamino-Oxidase-A (MAO-A) Inhibition on Skeletal Muscle Inflammation and Wasting through Pancreatic Ductal Adenocarcinoma in Triple Transgenic Mice
Published in Biomedicines (01-03-2023)“…Cancer cachexia describes a syndrome of muscle wasting and lipolysis that is still largely untreatable and negatively impacts prognosis, mobility, and…”
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10
MicroRNA-196a and -196b as Potential Biomarkers for the Early Detection of Familial Pancreatic Cancer
Published in Translational oncology (01-08-2014)“…Abstract Screening programs are recommended for individuals at risk (IAR) from families with familial pancreatic cancer (FPC). However, reliable imaging…”
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Variation in Precursor Lesions of Pancreatic Cancer among High-Risk Groups
Published in Clinical cancer research (15-01-2013)“…Pancreatic ductal adenocarcinoma (PDAC) surveillance programs are currently offered to high-risk individuals aiming to detect precursor lesions or PDAC at an…”
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12
Dissecting the role of toll‐like receptor 7 in pancreatic cancer
Published in Cancer medicine (Malden, MA) (01-04-2023)“…Background Toll‐like receptors (TLRs) are gaining attention for their potential to influence tumor biology both on the level of the tumor cells as well as on…”
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13
Extracellular Vesicle-Based Detection of Pancreatic Cancer
Published in Frontiers in cell and developmental biology (23-07-2021)“…Due to a grim prognosis, there is an urgent need to detect pancreatic ductal adenocarcinoma (PDAC) prior to metastasis. However, reliable diagnostic imaging…”
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14
Inflammation and Wasting of Skeletal Muscles in Kras-p53-Mutant Mice with Intraepithelial Neoplasia and Pancreatic Cancer-When Does Cachexia Start?
Published in Cells (Basel, Switzerland) (11-05-2022)“…Skeletal muscle wasting critically impairs the survival and quality of life in patients with pancreatic ductal adenocarcinoma (PDAC). To identify the local…”
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Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
Published in Journal of personalized medicine (02-07-2021)“…Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma…”
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German National Case Collection for familial pancreatic Cancer (FaPaCa) - acceptance and psychological aspects of a pancreatic cancer screening program
Published in Hereditary cancer in clinical practice (29-11-2018)“…Pancreatic cancer screening is recommended to individuals at risk (IAR) of familial pancreatic cancer (FPC) families, but little is known about the acceptance…”
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The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer
Published in Journal of clinical medicine (20-09-2018)“…Individuals at risk (IAR) of familial pancreatic cancer (FPC) are good candidates for screening. Unfortunately, neither reliable imaging modalities nor…”
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18
Laryngoscopy in thyroid surgery—essential standard or unnecessary routine?
Published in Surgery (01-12-2007)“…Background Preoperative and postoperative laryngoscopy has been recommended for diagnostic and forensic reasons as a standard procedure in all patients who…”
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Microarray analysis reveals differential expression of benign and malignant pheochromocytoma
Published in Endocrine-related cancer (01-09-2010)“…The diagnosis of a malignant pheochromocytoma (PC) can only be established by the presence of distant metastases, but a subset of apparently benign PCs develop…”
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Initial Parathyroid Surgery in 606 Patients with Renal Hyperparathyroidism
Published in World journal of surgery (01-02-2012)“…Background The aim of the present study was to evaluate the outcome of different surgical procedures for patients on permanent dialysis who underwent initial…”
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