Search Results - "SLATER, Andrew J"
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Performance of genotype imputation for rare variants identified in exons and flanking regions of genes
Published in PloS one (19-09-2011)“…Genotype imputation has the potential to assess human genetic variation at a lower cost than assaying the variants using laboratory techniques. The performance…”
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A comparison of internal validation techniques for multifactor dimensionality reduction
Published in BMC bioinformatics (22-07-2010)“…It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in…”
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Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
Published in Archives of neurology (Chicago) (01-01-2008)“…To identify single-nucleotide polymorphisms (SNPs) associated with risk and age at onset of Alzheimer disease (AD) in a genomewide association study of 469 438…”
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STOPGAP: a database for systematic target opportunity assessment by genetic association predictions
Published in Bioinformatics (Oxford, England) (01-09-2017)“…We developed the STOPGAP (Systematic Target OPportunity assessment by Genetic Association Predictions) database, an extensive catalog of human genetic…”
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Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation
Published in Diabetes (New York, N.Y.) (01-05-2012)“…Increased adiponectin levels have been shown to be associated with a lower risk of type 2 diabetes. To understand the relations between genetic variation at…”
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Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals
Published in American journal of human genetics (07-07-2016)“…Platelet production, maintenance, and clearance are tightly controlled processes indicative of platelets’ important roles in hemostasis and thrombosis…”
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
Published in American journal of human genetics (07-07-2016)“…Red blood cell (RBC) traits are important heritable clinical biomarkers and modifiers of disease severity. To identify coding genetic variants associated with…”
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Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases
Published in American journal of human genetics (07-07-2016)“…White blood cells play diverse roles in innate and adaptive immunity. Genetic association analyses of phenotypic variation in circulating white blood cell…”
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