Search Results - "SKRABANEK, Lucy"

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation by Figueroa, Maria E., Skrabanek, Lucy, Li, Yushan, Jiemjit, Anchalee, Fandy, Tamer E., Paietta, Elisabeth, Fernandez, Hugo, Tallman, Martin S., Greally, John M., Carraway, Hetty, Licht, Jonathan D., Gore, Steven D., Melnick, Ari

“…Increasing evidence shows aberrant hypermethylation of genes occurring in and potentially contributing to pathogenesis of myeloid malignancies. Several of…”
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The eukaryotic translation initiation factor eIF4E reprograms alternative splicing by Ghram, Mehdi, Morris, Gavin, Culjkovic‐Kraljacic, Biljana, Mars, Jean‐Clement, Gendron, Patrick, Skrabanek, Lucy, Revuelta, Maria Victoria, Cerchietti, Leandro, Guzman, Monica L, Borden, Katherine L B

“…Aberrant splicing is typically attributed to splice‐factor (SF) mutation and contributes to malignancies including acute myeloid leukemia (AML). Here, we…”
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An OCT2 / OCA-B / MEF2B Ternary Complex Controls the Activity and Architecture of an Essential Locus Control Region for Normal and Malignant Germinal Center B-Cells by Hellmuth, Johannes C, Chu, Chi-Shuen, Singh, Rajat, Skrabanek, Lucy A, Doane, Ashley, Elemento, Olivier, Roeder, Robert G., Melnick, Ari

“…The transcriptional repressor BCL6 is considered the master regulator of the germinal center (GC) reaction and is a key proto-oncogene in GC-derived lymphoma…”
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Computational Prediction of Protein–Protein Interactions by Skrabanek, Lucy, Saini, Harpreet K., Bader, Gary D., Enright, Anton J.

“…Recently a number of computational approaches have been developed for the prediction of protein–protein interactions. Complete genome sequencing projects have…”
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Stability of Eukaryotic Translation Initiation Factor 4E mRNA Is Regulated by HuR, and This Activity Is Dysregulated in Cancer by Topisirovic, Ivan, Siddiqui, Nadeem, Orolicki, Slobodanka, Skrabanek, Lucy A., Tremblay, Mathieu, Hoang, Trang, Borden, Katherine L. B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1 by Lugthart, Sanne, Figueroa, Maria E., Bindels, Eric, Skrabanek, Lucy, Valk, Peter J.M., Li, Yushan, Meyer, Stefan, Erpelinck-Verschueren, Claudia, Greally, John, Löwenberg, Bob, Melnick, Ari, Delwel, Ruud

“…DNA methylation patterns are frequently dysregulated in cancer, although little is known of the mechanisms through which specific gene sets become aberrantly…”
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PDZBase: a protein–protein interaction database for PDZ-domains by Beuming, Thijs, Skrabanek, Lucy, Niv, Masha Y., Mukherjee, Piali, Weinstein, Harel

“…PDZBase is a database that aims to contain all known PDZ-domain-mediated protein–protein interactions. Currently, PDZBase contains approximately 300 such…”
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eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR by Culjkovic, Biljana, Topisirovic, Ivan, Skrabanek, Lucy, Ruiz-Gutierrez, Melisa, Borden, Katherine L.B.

“…The eukaryotic translation initiation factor eIF4E is a critical modulator of cellular growth with functions in the nucleus and cytoplasm. In the cytoplasm,…”
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GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base by Khelashvili, George, Dorff, Kevin, Shan, Jufang, Camacho-Artacho, Marta, Skrabanek, Lucy, Vroling, Bas, Bouvier, Michel, Devi, Lakshmi A., George, Susan R., Javitch, Jonathan A., Lohse, Martin J., Milligan, Graeme, Neubig, Richard R., Palczewski, Krzysztof, Parmentier, Marc, Pin, Jean-Philippe, Vriend, Gerrit, Campagne, Fabien, Filizola, Marta

“…Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize…”
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Modeling activated states of GPCRs: the rhodopsin template by Niv, Masha Y, Skrabanek, Lucy, Filizola, Marta, Weinstein, Harel

“…Activation of G Protein-Coupled Receptors (GPCRs) is an allosteric mechanism triggered by ligand binding and resulting in conformational changes transduced by…”
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Features of Circulating Parainfluenza Virus Required for Growth in Human Airway by Palermo, Laura M, Uppal, Manik, Skrabanek, Lucy, Zumbo, Paul, Germer, Soren, Toussaint, Nora C, Rima, Bert K, Huey, Devra, Niewiesk, Stefan, Porotto, Matteo, Moscona, Anne

“…Respiratory paramyxoviruses, including the highly prevalent human parainfluenza viruses, cause the majority of childhood croup, bronchiolitis, and pneumonia,…”
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Mining expressed sequence tags identifies cancer markers of clinical interest by Campagne, Fabien, Skrabanek, Lucy

“…Gene expression data are a rich source of information about the transcriptional dis-regulation of genes in cancer. Genes that display differential regulation…”
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Amino Acid Substitutions in the Thyroglobulin Gene Are Associated with Susceptibility to Human and Murine Autoimmune Thyroid Disease by Ban, Yoshiyuki, Greenberg, David A., Concepcion, Erlinda, Skrabanek, Lucy, Villanueva, Ronald, Tomer, Yaron

“…The 8q24 locus, which contains the thyroglobulin (Tg) gene, was previously shown to be strongly linked with autoimmune thyroid disease (AITD). We sequenced all…”
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Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base by Skrabanek, Lucy, Murcia, Marta, Bouvier, Michel, Devi, Lakshmi, George, Susan R, Lohse, Martin J, Milligan, Graeme, Neubig, Richard, Palczewski, Krzysztof, Parmentier, Marc, Pin, Jean-Philippe, Vriend, Gerrit, Javitch, Jonathan A, Campagne, Fabien, Filizola, Marta

“…G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and…”
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Characterization of the Mouse Adeno-Associated Virus AAVS1 Ortholog by DUTHEIL, Nathalie, YOON-ROBARTS, Miran, WARD, Peter, HENCKAERTS, Els, SKRABANEK, Lucy, BERNS, Kenneth I, CAMPAGNE, Fabien, LINDEN, R. Michael

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human by McLysaght, Aoife, Enright, Anton J., Skrabanek, Lucy, Wolfe, Kenneth H.

“…Background: Knowledge of the amount of gene order and synteny conservation between two species gives insights to the extent and mechanisms of divergence. The…”
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DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia by Figueroa, Maria E., Lugthart, Sanne, Li, Yushan, Erpelinck-Verschueren, Claudia, Deng, Xutao, Christos, Paul J., Schifano, Elizabeth, Booth, James, van Putten, Wim, Skrabanek, Lucy, Campagne, Fabien, Mazumdar, Madhu, Greally, John M., Valk, Peter J.M., Löwenberg, Bob, Delwel, Ruud, Melnick, Ari

“…We hypothesized that DNA methylation distributes into specific patterns in cancer cells, which reflect critical biological differences. We therefore examined…”
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Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage by Chu, Chi-Shuen, Hellmuth, Johannes C., Singh, Rajat, Ying, Hsia-Yuan, Skrabanek, Lucy, Teater, Matthew R., Doane, Ashley S., Elemento, Olivier, Melnick, Ari M., Roeder, Robert G.

“…Locus control region (LCR) functions define cellular identity and have critical roles in diseases such as cancer, although the hierarchy of structural…”
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eIF4E is a central node of an RNA regulon that governs cellular proliferation by Culjkovic, Biljana, Topisirovic, Ivan, Skrabanek, Lucy, Ruiz-Gutierrez, Melisa, Borden, Katherine L.B

“…This study demonstrates that the eukaryotic translation initiation factor eIF4E is a critical node in an RNA regulon that impacts nearly every stage of cell…”
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The eukaryotic translation initiation factor eIF4E elevates steady-state m 7 G capping of coding and noncoding transcripts by Culjkovic-Kraljacic, Biljana, Skrabanek, Lucy, Revuelta, Maria V, Gasiorek, Jadwiga, Cowling, Victoria H, Cerchietti, Leandro, Borden, Katherine L B

“…Methyl-7-guanosine (m G) "capping" of coding and some noncoding RNAs is critical for their maturation and subsequent activity. Here, we discovered that…”
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