Search Results - "SKIBINSKI, David A. G"

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers by Low, Jenny G.H, Lee, Lawrence S, Ooi, Eng Eong, Ethirajulu, Kantharaj, Yeo, Pauline, Matter, Alex, Connolly, John E, Skibinski, David A.G, Saudan, Philippe, Bachmann, Martin, Hanson, Brendon J, Lu, Qingshu, Maurer-Stroh, Sebastian, Lim, Sam, Novotny-Diermayr, Veronica

“…Highlights • Phase I clinical trial with a novel VLP influenza vaccine produced in E. coli. • Randomized study with/without alhydrogel, total of 84 subjects. •…”
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Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine by Skibinski, David A G, Hanson, Brendon J, Lin, Yufang, von Messling, Veronika, Jegerlehner, Andrea, Tee, Jason Boon Sern, Chye, De Hoe, Wong, Steven K K, Ng, Amanda A P, Lee, Hui Yin, Au, Bijin, Lee, Bernett T K, Santoso, Lucia, Poidinger, Michael, Fairhurst, Anna-Marie, Matter, Alex, Bachmann, Martin F, Saudan, Philippe, Connolly, John E

“…Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the…”
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Aluminum adjuvant dose guidelines in vaccine formulation for preclinical evaluations by Vecchi, Simone, Bufali, Simone, Skibinski, David A G, O'Hagan, Derek T, Singh, Manmohan

“…Aluminum (Al) salt-based adjuvants are present in a large variety of licensed vaccines and their use is widely considered for formulations in clinical trials…”
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Helicobacter pylori Vacuolating Toxin Mutant That Fails To Oligomerize Has a Dominant Negative Phenotype by Genisset, Christophe, Galeotti, Cesira L, Lupetti, Pietro, Mercati, David, Skibinski, David A. G, Barone, Silvia, Battistutta, Roberto, de Bernard, Marina, Telford, John L

“…Most Helicobacter pylori strains secrete a toxin (VacA) that causes massive vacuolization of target cells and which is a major virulence factor of H. pylori…”
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The Cell-Specific Phenotype of the Polymorphic vacA Midregion Is Independent of the Appearance of the Cell Surface Receptor Protein Tyrosine Phosphatase β by SKIBINSKI, David A. G, GENISSET, Christophe, BARONE, Silvia, TELFORD, John L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine by Skibinski, David A. G., Jones, Leigh Ann, Zhu, Yuan O., Xue, Lin Wu, Au, Bijin, Lee, Bernett, Naim, Ahmad Nazri Mohamed, Lee, Audrey, Kaliaperumal, Nivashini, Low, Jenny G. H., Lee, Lawrence S., Poidinger, Michael, Saudan, Philippe, Bachmann, Martin, Ooi, Eng Eong, Hanson, Brendon J., Novotny-Diermayr, Veronica, Matter, Alex, Fairhurst, Anna-Marie, Hibberd, Martin L., Connolly, John E.

“…Cell mediated immunity plays a vital role in defense against influenza infection in humans. Less is known about the role of vaccine-induced cell mediated…”
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A simple strategy for sample annotation error detection in cytometry datasets by Smithmyer, Megan E., Wiedeman, Alice E., Skibinski, David A. G., Savage, Adam K., Acosta‐Vega, Carolina, Scheiding, Sheila, Gersuk, Vivian H., O'Rourke, Colin, Long, S. Alice, Buckner, Jane H., Speake, Cate

“…Mislabeling samples or data with the wrong participant information can affect study integrity and lead investigators to draw inaccurate conclusions. Quality…”
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Noninvasive detection of PD-L1 on circulating tumor cells in patient blood samples by Skibinski, David AG

“…In a number of tumor types including metastatic melanoma bladder cancer, non-small-cell lung cancer (NSCLC) and gastric cancer there is a consistent positive…”
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Flow cytometry: An alternative method for direct quantification of antigens adsorbed to aluminum hydroxide adjuvant by Ugozzoli, Mildred, Laera, Donatello, Nuti, Sandra, Skibinski, David A.G., Bufali, Simone, Sammicheli, Chiara, Tavarini, Simona, Singh, Manmohan, O’Hagan, Derek T.

“…Flow cytometry (FC) has been widely used in biological research; however, its use for vaccine characterization has been very limited. Here we describe the…”
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Combination vaccines by Skibinski, David Ag, Baudner, Barbara C, Singh, Manmohan, O'Hagan, Derek T

“…The combination of diphtheria, tetanus, and pertussis vaccines into a single product has been central to the protection of the pediatric population over the…”
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A preliminary study for the assessment of PD-L1 and PD-L2 on circulating tumor cells by microfluidic-based chipcytometry by Teo, Jinkai, Mirenska, Anja, Tan, Meihui, Lee, Yifang, Oh, Janice, Hong, Lewis Z, Wnek, Richard, Yap, Yoon-Sim, Shih, Shian-Jiun, S Bhagat, Ali Asgar, Chin, Chih-Liang, Skibinski, David AG

“…Expression of PD-L1 in the tumor is associated with more favorable responses to anti-PD-1 therapy in multiple cancers. However, obtaining tumor biopsies for…”
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Rational design of small molecules as vaccine adjuvants by Wu, Tom Y-H, Singh, Manmohan, Miller, Andrew T, De Gregorio, Ennio, Doro, Francesco, D'Oro, Ugo, Skibinski, David A G, Mbow, M Lamine, Bufali, Simone, Herman, Ann E, Cortez, Alex, Li, Yongkai, Nayak, Bishnu P, Tritto, Elaine, Filippi, Christophe M, Otten, Gillis R, Brito, Luis A, Monaci, Elisabetta, Li, Chun, Aprea, Susanna, Valentini, Sara, Calabrό, Samuele, Laera, Donatello, Brunelli, Brunella, Caproni, Elena, Malyala, Padma, Panchal, Rekha G, Warren, Travis K, Bavari, Sina, O'Hagan, Derek T, Cooke, Michael P, Valiante, Nicholas M

“…Adjuvants increase vaccine potency largely by activating innate immunity and promoting inflammation. Limiting the side effects of this inflammation is a major…”
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Regulation of the Hydrogenase-4 Operon of Escherichia coli by the σ54-Dependent Transcriptional Activators FhlA and HyfR by Skibinski, David A. G., Golby, Paul, Chang, Yung-Sheng, Sargent, Frank, Hoffman, Ralf, Harper, R., Guest, John R., Attwood, Margaret M., Berks, Ben C., Andrews, Simon C.

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sex-biased heteroplasmy and mitochondrial DNA inheritance in the musselMytilus galloprovincialis Lmk by Quesada, Humberto, Skibinski, David A. G., Skibinski, David O. F.

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Regulation of the hydrogenase-4 operon of Escherichia coli by the sigma(54)-dependent transcriptional activators FhlA and HyfR by Skibinski, David A G, Golby, Paul, Chang, Yung-Sheng, Sargent, Frank, Hoffman, Ralf, Harper, R, Guest, John R, Attwood, Margaret M, Berks, Ben C, Andrews, Simon C

“…The hyf locus (hyfABCDEFGHIJ-hyfR-focB) of Escherichia coli encodes a putative 10-subunit hydrogenase complex (hydrogenase-4 [Hyf]); a potential…”
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Cell-Specific Phenotype of the Polymorphic vacA Midregion Is Independent of the Appearance of the Cell Surface Receptor Protein Tyrosine Phosphatase {szligbeta} by Skibinski, David A. G, Genisset, Christophe, Barone, Silvia, Telford, John L

“…There are two alleles, m1 and m2, of the midregion of the vacuolating cytotoxin gene (vacA) of Helicobacter pylori which code for toxins with different cell…”
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Regulation of the hydrogenase-4 operon of Escherichia coli by the sigma54-dependent transcriptional activators FhlA and HyfR by Skibinski, David A G, Golby, Paul, Yung-Sheng, Chang, Sargent, Frank

“…The hyf locus (hyfABCDEFGHIJ-hyfR-focB) of Escherichia coli encodes a putative 10-subunit hydrogenase complex (hydrogenase-4 [Hyf]); a potential…”
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Regulation of the Hydrogenase-4 Operon of Escherichia coli by the σ 54 -Dependent Transcriptional Activators FhlA and HyfR by Skibinski, David A. G., Golby, Paul, Chang, Yung-Sheng, Sargent, Frank, Hoffman, Ralf, Harper, R., Guest, John R., Attwood, Margaret M., Berks, Ben C., Andrews, Simon C.

“…ABSTRACT The hyf locus ( hyfABCDEFGHIJ-hyfR-focB ) of Escherichia coli encodes a putative 10-subunit hydrogenase complex (hydrogenase-4 [Hyf]); a potential σ…”
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Enhanced Neutralizing Antibody Titers and Th1 Polarization from a Novel Escherichia coli Derived Pandemic Influenza Vaccine: e76571 by Skibinski, David AG, Hanson, Brendon J, Lin, Yufang, Messling, Veronika von, Jegerlehner, Andrea, Tee, Jason BoonSern, Chye, De Hoe, Wong, Steven KK, Ng, Amanda AP, Lee, Hui Yin

“…Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the…”
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