Search Results - "SKAFTNESMO, Kai Ove"

Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9-mediated HDR in Atlantic salmon by Straume, Anne Hege, Kjærner-Semb, Erik, Ove Skaftnesmo, Kai, Güralp, Hilal, Kleppe, Lene, Wargelius, Anna, Edvardsen, Rolf Brudvik

“…Precise gene editing such as CRISPR/Cas9-mediated homology directed repair (HDR) can increase our understanding of gene function and improve traits of…”
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Angiogenesis-Independent Tumor Growth Mediated by Stem-Like Cancer Cells by Sakariassen, Per Ø., Prestegarden, Lars, Wang, Jian, Skaftnesmo, Kai-Ove, Mahesparan, Rupavathana, Molthoff, Carla, Sminia, Peter, Sundlisæter, Eirik, Misra, Anjan, Tysnes, Berit Bølge, Chekenya, Martha, Peters, Hans, Lende, Gabriel, Kalland, Karl Henning, Øyan, Anne M., Petersen, Kjell, Jonassen, Inge, van der Kogel, Albert, Feuerstein, Burt G., Terzis, A. Jorge A., Bjerkvig, Rolf, Enger, Per Øyvind

“…In this work, highly infiltrative brain tumors with a stem-like phenotype were established by xenotransplantation of human brain tumors in immunodeficient nude…”
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Targeted mutagenesis in Atlantic salmon (Salmo salar L.) using the CRISPR/Cas9 system induces complete knockout individuals in the F0 generation by Edvardsen, Rolf B, Leininger, Sven, Kleppe, Lene, Skaftnesmo, Kai Ove, Wargelius, Anna

“…Understanding the biological function behind key proteins is of great concern in Atlantic salmon, both due to a high commercial importance and an interesting…”
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Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon by Wargelius, Anna, Leininger, Sven, Skaftnesmo, Kai Ove, Kleppe, Lene, Andersson, Eva, Taranger, Geir Lasse, Schulz, Rüdiger W, Edvardsen, Rolf B

“…Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic integrity of wild populations. Using germ cell-free fish in…”
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Transcriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon by Kleppe, Lene, Edvardsen, Rolf Brudvik, Furmanek, Tomasz, Andersson, Eva, Skaftnesmo, Kai Ove, Thyri Segafredo, Frida, Wargelius, Anna

“…Sustainability challenges are currently hampering an increase in salmon production. Using sterile salmon can solve problems with precocious puberty and genetic…”
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Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors by Straume, Anne Hege, Kjaerner-Semb, Erik, Skaftnesmo, Kai Ove, Güralp, Hilal, Lillico, Simon, Wargelius, Anna, Edvardsen, Rolf Brudvik

“…Abstract Background New breeding technologies (NBT) using CRISPR/Cas9-induced homology directed repair (HDR) has the potential to expedite genetic improvement…”
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Nanopore sequencing provides snapshots of the genetic variation within salmonid alphavirus-3 (SAV3) during an ongoing infection in Atlantic salmon (Salmo salar) and brown trout (Salmo trutta) by Roh, HyeongJin, Skaftnesmo, Kai Ove, Kannimuthu, Dhamotharan, Madhun, Abdullah, Patel, Sonal, Kvamme, Bjørn Olav, Morton, H Craig, Grove, Søren

“…Frequent RNA virus mutations raise concerns about evolving virulent variants. The purpose of this study was to investigate genetic variation in salmonid…”
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Divergent Activity of the Pseudogene PTENP1 in ER-Positive and Negative Breast Cancer by Yndestad, Synnøve, Austreid, Eilin, Skaftnesmo, Kai Ove, Lønning, Per Eystein, Eikesdal, Hans Petter

“…Transcripts derived from the function as decoys to adsorb miRNAs targeting the tumor suppressor for degradation, and upregulation is known to inhibit growth in…”
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Intercellular transfer of transferrin receptor by a contact‐, Rab8‐dependent mechanism involving tunneling nanotubes by Burtey, Anne, Wagner, Marek, Hodneland, Erlend, Skaftnesmo, Kai Ove, Schoelermann, Julia, Mondragon, Ivan Rios, Espedal, Heidi, Golebiewska, Anna, Niclou, Simone P., Bjerkvig, Rolf, Kögel, Tanja, Gerdes, Hans‐Hermann

“…ABSTRACT Intercellular communication between cancer cells, especially between cancer and stromal cells, plays an important role in disease progression. We…”
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MicroRNA regulation of the synaptic plasticity-related gene Arc by Wibrand, Karin, Pai, Balagopal, Siripornmongcolchai, Taweeporn, Bittins, Margarethe, Berentsen, Birgitte, Ofte, May Lillian, Weigel, Arwed, Skaftnesmo, Kai Ove, Bramham, Clive R

“…Expression of activity-regulated cytoskeleton associated protein (Arc) is crucial for diverse types of experience-dependent synaptic plasticity and long-term…”
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EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis by Talasila, Krishna M., Soentgerath, Anke, Euskirchen, Philipp, Rosland, Gro V., Wang, Jian, Huszthy, Peter C., Prestegarden, Lars, Skaftnesmo, Kai Ove, Sakariassen, Per Øystein, Eskilsson, Eskil, Stieber, Daniel, Keunen, Olivier, Brekka, Narve, Moen, Ingrid, Nigro, Janice M., Vintermyr, Olav K., Lund-Johansen, Morten, Niclou, Simone, Mørk, Sverre J., Enger, Per Øyvind, Bjerkvig, Rolf, Miletic, Hrvoje

“…Angiogenesis is regarded as a hallmark of cancer progression and it has been postulated that solid tumor growth depends on angiogenesis. At present, however,…”
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Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model by SUNDSTRØM, Terje, DAPHU, Inderjit, LUND-JOHANSEN, Morten, BJERKVIG, Rolf, THORSEN, Frits, WENDELBO, Ingvild, HODNELAND, Erlend, LUNDERVOLD, Arvid, IMMERVOLL, Heike, OVE SKAFTNESMO, Kai, BABIC, Michal, JENDELOVA, Pavla, SYKOVA, Eva

“…Biologic and therapeutic advances in melanoma brain metastasis are hampered by the paucity of reproducible and predictive animal models. In this work, we…”
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Targeting the NG2/CSPG4 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma by Wang, Jian, Svendsen, Agnete, Kmiecik, Justyna, Immervoll, Heike, Skaftnesmo, Kai Ove, Planagumà, Jesús, Reed, Rolf Kåre, Bjerkvig, Rolf, Miletic, Hrvoje, Enger, Per Øyvind, Rygh, Cecilie Brekke, Chekenya, Martha

“…Aberrant expression of the progenitor marker Neuron-glia 2 (NG2/CSPG4) or melanoma proteoglycan on cancer cells and angiogenic vasculature is associated with…”
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Glioma Cell Populations Grouped by Different Cell Type Markers Drive Brain Tumor Growth by PRESTEGARDEN, Lars, SVENDSEN, Agnete, ENGER, Per Øyvind, JIAN WANG, SLEIRE, Linda, SKAFTNESMO, Kai Ove, BJERKVIG, Rolf, TAO YAN, ASKLAND, Lasse, PERSSON, Andreas, SAKARIASSEN, Per Øystein

“…Although CD133 has been proposed as a marker for brain tumor-initiating cells, studies show that a tumorigenic potential exists among CD133(-) glioma cells as…”
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Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies by Crespo, Diego, Skaftnesmo, Kai Ove, Kjærner-Semb, Erik, Yilmaz, Ozlem, Norberg, Birgitta, Olausson, Sara, Vogelsang, Petra, Bogerd, Jan, Kleppe, Lene, Edvardsen, Rolf B, Andersson, Eva, Wargelius, Anna, Hansen, Tom J, Fjelldal, Per Gunnar, Schulz, Rüdiger W

“…Precocious male maturation causes reduced welfare and increased production costs in Atlantic salmon ( ) aquaculture. The pituitary produces and releases…”
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Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis by Sundstrøm, Terje, Prestegarden, Lars, Azuaje, Francisco, Aasen, Synnøve Nymark, Røsland, Gro Vatne, Varughese, Jobin K, Bahador, Marzieh, Bernatz, Simon, Braun, Yannick, Harter, Patrick N, Skaftnesmo, Kai Ove, Ingham, Elizabeth S, Mahakian, Lisa M, Tam, Sarah, Tepper, Clifford G, Petersen, Kjell, Ferrara, Katherine W, Tronstad, Karl Johan, Lund-Johansen, Morten, Beschorner, Rudi, Bjerkvig, Rolf, Thorsen, Frits

“…Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control…”
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Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide by Yan, Tao, Skaftnesmo, Kai Ove, Leiss, Lina, Sleire, Linda, Wang, Jian, Li, Xingang, Enger, Per Øyvind

“…Expression of neuronal elements has been identified in various glial tumors, and glioblastomas (GBMs) with neuronal differentiation patterns have reportedly…”
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Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells by Crespo, Diego, Assis, Luiz H. C., Zhang, Yu Ting, Safian, Diego, Furmanek, Tomasz, Skaftnesmo, Kai Ove, Norberg, Birgitta, Ge, Wei, Choi, Yung-Ching, den Broeder, Marjo J., Legler, Juliette, Bogerd, Jan, Schulz, Rüdiger W.

“…Pituitary hormones can use local signaling molecules to regulate target tissue functions. In adult zebrafish testes, follicle-stimulating hormone (Fsh)…”
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In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways by Daphu, Inderjit, Horn, Sindre, Stieber, Daniel, Varughese, Jobin K, Spriet, Endy, Dale, Hege Avsnes, Skaftnesmo, Kai Ove, Bjerkvig, Rolf, Thorsen, Frits

“…Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E…”
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Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy by Huszthy, Peter C, Giroglou, Tsanan, Tsinkalovsky, Oleg, Euskirchen, Philipp, Skaftnesmo, Kai Ove, Bjerkvig, Rolf, von Laer, Dorothee, Miletic, Hrvoje

“…Glioblastoma is the most frequent and most malignant primary brain tumor with a poor prognosis. The translation of therapeutic strategies for glioblastoma from…”
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