Search Results - "SKÅLHEGG, B. S"

Ghrelin is related to lower brain reward activation during touch by Pfabigan, D. M., Frogner, E. R., Schéle, E., Thorsby, P. M., Skålhegg, B. S., Dickson, S. L., Sailer, U.

“…The gut hormone ghrelin drives food motivation and increases food intake, but it is also involved in the anticipation of and response to rewards other than…”
Get full text

Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa by Hereng, T.H., Elgstøen, K.B.P., Cederkvist, F.H., Eide, L., Jahnsen, T., Skålhegg, B.S., Rosendal, K.R.

“…BACKGROUND There has been an ongoing debate in the reproductive field about whether mammalian spermatozoa rely on glycolysis, oxidative phosphorylation or both…”
Get full text

Metabolic profiling of synovial tissue shows altered glucose and choline metabolism in rheumatoid arthritis samples by Volchenkov, R, Dung Cao, M, Elgstøen, KB, Goll, GL, Eikvar, K, Bjørneboe, O, Bathen, TF, Holen, HL, Kvien, TK, Skålhegg, BS

Get full text

Serum albumin and HCO3− regulate separate pools of ATP in human spermatozoa by Hereng, T.H., Elgstøen, K.B.P., Eide, L., Rosendal, K.R., Skålhegg, B.S.

“…STUDY QUESTION Do the known capacitating agents HCO3− and serum albumin regulate the generation of ATP required for sperm motility and capacitation? SUMMARY…”
Get full text

A novel isoform of human cyclic 3', 5'-adenosine monophosphate-dependent protein kinase, Cα-s, localizes to sperm midpiece by REINTON, N, ØRSTAVIK, S, HAUGEN, T. B, JAHNSEN, T, TASKEN, K, SKALHEGG, B. S

“…Using rapid amplification of cDNA ends, a cDNA encoding a novel splice variant of the human C alpha catalytic subunit of cAMP-dependent protein kinase (PKA)…”
Get full text

Location of cAMP-Dependent Protein Kinase Type I with the TCR-CD3 Complex by Skålhegg, Bjørn S., Taskén, Kjetil, Hansson, Vidar, Huitfeldt, Henrik S., Jahnsen, Tore, Lea, Tor

“…Selective activation of cyclic adenosine 3′,5′-monophosphate (cAMP)-dependent protein kinase type I (cAKI), but not type II, is sufficient to mediate…”
Get full text

Increased Activation of Protein Kinase A Type I Contributes to the T Cell Deficiency in Common Variable Immunodeficiency by Aukrust, Pal, Aandahl, Einar Martin, Skalhegg, Bjorn S, Nordoy, Ingvild, Hansson, Vidar, Tasken, Kjetil, Froland, Stig S, Muller, Fredrik

“…The molecular mechanisms underlying the T cell dysfunction often present in common variable immunodeficiency (CVI) are not established. cAMP-dependent protein…”
Get full text

Cellular location and age-dependent changes of the regulatory subunits of cAMP-dependent protein kinase in rat testis by Landmark, B F, Oyen, O, Skålhegg, B S, Fauske, B, Jahnsen, T, Hansson, V

“…This study was undertaken to examine the expression and cellular location of the various cAMP-dependent protein kinase (PKA) subunits in different testicular…”
Get full text

Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor by Vang, T, Torgersen, K M, Sundvold, V, Saxena, M, Levy, F O, Skålhegg, B S, Hansson, V, Mustelin, T, Taskén, K

“…In T cells, cAMP-dependent protein kinase (PKA) type I colocalizes with the T cell receptor-CD3 complex (TCR/CD3) and inhibits T cell function via a previously…”
Get full text

The Gene Encoding the Cγ Catalytic Subunit of cAMP-Dependent Protein Kinase Is a Transcribed Retroposon by Reinton, Nils, Haugen, Trine B., Ørstavik, Sigurd, Skålhegg, Bjørn S., Hansson, Vidar, Jahnsen, Tore, Taskén, Kjetil

“…Three different catalytic isoforms of cAMP-dependent protein kinase have been identified (Cα, Cβ, and Cγ). We report the cloning and characterization of the…”
Get full text

Novel isozymes of cAMP-dependent protein kinase exist in human cells due to formation of RI alpha-RI beta heterodimeric complexes by TASKEN, K, SKÅLHEGG, B. S, SOLBERG, R, ANDERSSON, K. B, TAYLOR, S. S, LEA, T, BLOMHOFF, H. K, JAHNSEN, T, HANSSON, V

“…We report that a human neoplastic B cell line (Reh) contains cAMP-dependent protein kinase (cAK) type I (cAKI), but is practically devoid of cAK type II…”
Get full text

HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics by Martins, S B, Eide, T, Steen, R L, Jahnsen, T, Skålhegg B, S, Collas, P

“…We report a role for HA95, a nuclear protein with high homology to the nuclear A-kinase anchoring protein AKAP95, in the regulation of nuclear…”
Get full text

Structure, function, and regulation of human cAMP-dependent protein kinases by Taskén, K, Skålhegg, B S, Taskén, K A, Solberg, R, Knutsen, H K, Levy, F O, Sandberg, M, Orstavik, S, Larsen, T, Johansen, A K, Vang, T, Schrader, H P, Reinton, N T, Torgersen, K M, Hansson, V, Jahnsen, T

“…A large number of hormones, neurotransmitters, and other signaling substances that bind to G-protein-coupled cell-surface receptors have their signals converge…”
Get more information

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450 by Witczak, Oliwia, Skålhegg, Bjørn S., Keryer, Guy, Bornens, Michel, Taskén, Kjetil, Jahnsen, Tore, Ørstavik, Sigurd

“…A combination of protein kinase A type II (RII) overlay screening, database searches and PCR was used to identify a centrosomal A‐kinase anchoring protein. A…”
Get full text

Cyclic AMP-dependent protein kinase type I mediates the inhibitory effects of 3',5'-cyclic adenosine monophosphate on cell replication in human T lymphocytes by SKÅLHEGG, B. S, LANDMARK, B. F, DØSKELAND, S. O, HANSSON, V, LEA, T, JAHNSEN, T

“…Human T lymphocytes were used as a model system to study the expression and roles of cAMP-dependent protein kinase isozymes (cAKI and cAKII) in cAMP-induced…”
Get full text

Lipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapy by Fredriksen, J., Ueland, T., Dyrøy, E., Halvorsen, B., Melby, K., Melbye, L., Skalhegg, B. S., Bohov, P., Skorve, J., Berge, R. K., Aukrust, P., Frøland, S. S.

“…Background  Highly active antiretroviral therapy (HAART) often leads to a dramatic improvement in clinical, viral and immunologic parameters in HIV‐infected…”
Get full text

Protein kinase A type I antagonist restores immune responses of T cells from HIV‐infected patients by Aandahl, Einar Martin, Aukrust, Pål, Skålhegg, Bj⊘rn S., Müller, Fredrik, Fr⊘land, Stig S., Hansson, Vidar, Taskén, Kjetil

“…ABSTRACT Cyclic AMP‐dependent protein kinase A (PKA) type I has been established as an acute inhibitor of T cell activation. For this reason, we investigated…”
Get full text

Cyclic AMP sensitive signalling by the CD28 marker requires concomitant stimulation by the T-cell antigen receptor (TCR/CD3) complex by Skålhegg, B S, Rasmussen, A M, Taskén, K, Hansson, V, Jahnsen, T, Lea, T

“…We have previously demonstrated that activation of cAMP-dependent protein kinase (cAK) type I (cAKI, RI alpha 2-C beta 2) mediates the inhibitory effects of…”
Get more information

CDK1-mediated phosphorylation of the RIIα regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIα from centrosomes at mitosis by Carlson, Cathrine R., Witczak, Oliwia, Vossebein, Lutz, Labbé, Jean-Claude, Skålhegg, Bjørn S., Keryer, Guy, Herberg, Friedrich W., Collas, Philippe, Taskén, Kjetil

“…Protein kinase A regulatory subunit RIIα is tightly bound to centrosomal structures during interphase through interaction with the A-kinase anchoring protein…”
Get full text

Differential Localization of Protein Kinase A Type II Isozymes in the Golgi–Centrosomal Area by Keryer, Guy, Skålhegg, Bjørn S., Landmark, Brynjar F., Hansson, Vidar, Jahnsen, Tore, Taskén, Kjetil

“…Selectivity in the action of cAMP may be mediated by compartmentalized pools of cyclic AMP-dependent protein kinase (PKA). PKA type II is directed to different…”
Get full text