Search Results - "SITTINGER, K."

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment by WATZKA, M., GEISEN, C., BEVANS, C. G., SITTINGER, K., SPOHN, G., ROST, S., SEIFRIED, E., MÜLLER, C. R., OLDENBURG, J.

“…Background: Vitamin K 2,3‐epoxide reductase complex subunit 1 (VKORC1) is the molecular target of oral anticoagulants. Mutations in VKORC1 cause partial or…”
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VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation by Geisen, Christof, Watzka, Matthias, Sittinger, Katja, Steffens, Michael, Daugela, Laurynas, Seifried, Erhard, Müller, Clemens R, Wienker, Thomas F, Oldenburg, Johannes

“…In order to elucidate the role of VCORC1 sequence variants in warfarin sensitivity, we established a complete SNP map of the VKORC1 gene locus in 200 blood…”
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Impact of pharmacokinetic (CYP2C9) and pharmacodynamic (VKORC1, F7, GGCX, CALU, EPHX1) gene variants on the initiation and maintenance phases of phenprocoumon therapy by Luxembourg, Baete, Schneider, Katharina, Sittinger, Katja, Toennes, Stefan W, Seifried, Erhard, Lindhoff-Last, Edelgard, Oldenburg, Johannes, Geisen, Christof

“…Compared to warfarin, little is known about the effect of pharmacogenomics on the inter-individual variability of phenprocoumon therapy. In a retrospective…”
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