Search Results - "SITBON, Olivier"
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Selexipag for the Treatment of Pulmonary Arterial Hypertension
Published in The New England journal of medicine (24-12-2015)“…Among over 1100 patients with pulmonary arterial hypertension who received selexipag, an oral selective IP prostacyclin-receptor agonist, or placebo, the risk…”
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Current and future treatments of pulmonary arterial hypertension
Published in British journal of pharmacology (01-01-2021)“…Therapeutic options for pulmonary arterial hypertension (PAH) have increased over the last decades. The advent of pharmacological therapies targeting the…”
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Treatment of Pulmonary Arterial Hypertension
Published in The New England journal of medicine (30-09-2004)“…Pulmonary arterial hypertension, which is characterized by vascular proliferation and remodeling of small pulmonary vessels, leads to a progressive increase in…”
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French experience of balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension
Published in The European respiratory journal (01-05-2019)“…To evaluate safety and efficacy of balloon pulmonary angioplasty (BPA) in a large cohort of patients with chronic thromboembolic pulmonary hypertension…”
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Selexipag for the treatment of connective tissue disease-associated pulmonary arterial hypertension
Published in The European respiratory journal (01-08-2017)“…Patients with connective tissue disease-associated pulmonary arterial hypertension (PAH-CTD) have a poor prognosis compared with other aetiologies. The…”
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Beyond a single pathway: combination therapy in pulmonary arterial hypertension
Published in European respiratory review (01-12-2016)“…There is a strong rationale for combining therapies to simultaneously target three of the key pathways implicated in the pathogenesis of pulmonary arterial…”
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External validation of a refined four-stratum risk assessment score from the French pulmonary hypertension registry
Published in The European respiratory journal (01-06-2022)“…Introduction Contemporary risk assessment tools categorise patients with pulmonary arterial hypertension (PAH) as low, intermediate or high risk. A minority of…”
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Long-term outcomes of dasatinib-induced pulmonary arterial hypertension: a population-based study
Published in The European respiratory journal (01-07-2017)“…This study aimed to describe the long-term outcomes of pulmonary arterial hypertension (PAH) induced by dasatinib.21 incident, right heart…”
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Epoprostenol and pulmonary arterial hypertension: 20 years of clinical experience
Published in European respiratory review (01-01-2017)“…Epoprostenol was the first therapy to be approved for the treatment of pulmonary arterial hypertension (PAH). In the 20 years since the introduction of this…”
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Criteria for diagnosis of exercise pulmonary hypertension
Published in The European respiratory journal (01-09-2015)“…The previous definition of exercise pulmonary hypertension (PH) with a mean pulmonary artery pressure (mPAP) >30 mmHg was abandoned because healthy individuals…”
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Prognostic Value of Follow-Up Hemodynamic Variables After Initial Management in Pulmonary Arterial Hypertension
Published in Circulation (New York, N.Y.) (13-02-2018)“…BACKGROUND:Hemodynamic variables such as cardiac index and right atrial pressure have consistently been associated with survival in pulmonary arterial…”
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Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension
Published in The European respiratory journal (01-10-2017)“…Studies reporting the effects of modern strategies with pulmonary arterial hypertension (PAH)-targeted therapies in sarcoidosis-associated pulmonary…”
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Pulmonary veno-occlusive disease
Published in The European respiratory journal (01-05-2016)“…Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension (PH) characterised by preferential remodelling of the pulmonary venules. In…”
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Clinical trial design and new therapies for pulmonary arterial hypertension
Published in The European respiratory journal (01-01-2019)“…Until 20 years ago the treatment of pulmonary arterial hypertension (PAH) was based on case reports and small series, and was largely ineffectual. As a deeper…”
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Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
Published in The New England journal of medicine (29-08-2013)“…In an event-driven trial, macitentan (an endothelin-receptor antagonist) at a dose of 3 or 10 mg was compared with placebo in patients with symptomatic…”
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EIF2AK4 mutations cause pulmonary veno-occlusive disease, a recessive form of pulmonary hypertension
Published in Nature genetics (01-01-2014)“…Florent Soubrier and colleagues identify biallelic mutations in EIF2AK4 as a major cause of pulmonary veno-occlusive disease, a rare form of pulmonary…”
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Pulmonary Arterial Hypertension in Patients Treated by Dasatinib
Published in Circulation (New York, N.Y.) (01-05-2012)“…The French pulmonary hypertension (PH) registry allows the survey of epidemiological trends. Isolated cases of precapillary PH have been reported in patients…”
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Management of pulmonary arterial hypertension in patients aged over 65 years
Published in European heart journal supplements (01-12-2019)“…Historically, pulmonary arterial hypertension (PAH) has been considered a disease of young adults, but over the last three decades, the average age at…”
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Initial dual oral combination therapy in pulmonary arterial hypertension
Published in The European respiratory journal (01-06-2016)“…Treatment for pulmonary arterial hypertension (PAH) has been underpinned by single-agent therapy to which concomitant drugs are added sequentially when…”
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Treatment Goals of Pulmonary Hypertension
Published in Journal of the American College of Cardiology (24-12-2013)“…With significant therapeutic advances in the field of pulmonary arterial hypertension, the need to identify clinically relevant treatment goals that correlate…”
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