Search Results - "SIRTORI, Cesare"

The pharmacology of statins by Sirtori, Cesare R.

“…Statins, inhibitors of the hydroxymethylglutaryl-CoA (HMG-CoA) reductase enzyme, are molecules of fungal origin. By inhibiting a key step in the sterol…”
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PPAR Agonists and Metabolic Syndrome: An Established Role? by Botta, Margherita, Audano, Matteo, Sahebkar, Amirhossein, Sirtori, Cesare R, Mitro, Nico, Ruscica, Massimiliano

“…Therapeutic approaches to metabolic syndrome (MetS) are numerous and may target lipoproteins, blood pressure or anthropometric indices. Peroxisome…”
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Side effects of statins: from pathophysiology and epidemiology to diagnostic and therapeutic implications by Ruscica, Massimiliano, Ferri, Nicola, Banach, Maciej, Sirtori, Cesare R, Corsini, Alberto

“…Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, has proven beneficial preventive effects on cardiovascular events…”
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Proprotein Convertase Subtilisin/Kexin Type 9: A View beyond the Canonical Cholesterol-Lowering Impact by Macchi, Chiara, Ferri, Nicola, Sirtori, Cesare R, Corsini, Alberto, Banach, Maciej, Ruscica, Massimiliano

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Carotid IMT and atherosclerosis: “Calling things by name” by Sirtori, Cesare R.

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PCSK9 inhibition and inflammation: A narrative review by Ruscica, Massimiliano, Tokgözoğlu, Lale, Corsini, Alberto, Sirtori, Cesare R.

“…Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality despite excellent pharmacological and revascularization…”
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Challenges and Opportunities for Mycoprotein-Based Food Products by Sirtori, Cesare R., Lammi, Carmen

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Clinical approach to the inflammatory etiology of cardiovascular diseases by Ruscica, Massimiliano, Corsini, Alberto, Ferri, Nicola, Banach, Maciej, Sirtori, Cesare R.

“…[Display omitted] Inflammation is an obligatory marker of arterial disease, both stemming from the inflammatory activity of cholesterol itself and from…”
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The Role of High-Density Lipoprotein Cholesterol in 2022 by Sirtori, Cesare R., Corsini, Alberto, Ruscica, Massimiliano

“…Purpose of the Review High-density lipoproteins (HDL) are responsible for the transport in plasma of a large fraction of circulating lipids, in part from…”
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Bempedoic Acid: for Whom and When by Ruscica, Massimiliano, Sirtori, Cesare R., Carugo, Stefano, Banach, Maciej, Corsini, Alberto

“…Purpose of Review The aim of creating an orally active non-statin cholesterol-lowering drug was achieved with bempedoic acid, a small linear molecule providing…”
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Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: New therapeutic approaches for the treatment of atherogenic dyslipidemia by Ruscica, Massimiliano, Zimetti, Francesca, Adorni, Maria Pia, Sirtori, Cesare R., Lupo, Maria Giovanna, Ferri, Nicola

“…[Display omitted] Among the determinants of atherosclerotic cardiovascular disease (ASCVD), genetic and experimental evidence has provided data on a major role…”
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Nonalcoholic fatty liver disease or metabolic dysfunction‐associated fatty liver disease diagnoses and cardiovascular diseases: From epidemiology to drug approaches by Dongiovanni, Paola, Paolini, Erika, Corsini, Alberto, Sirtori, Cesare R., Ruscica, Massimiliano

“…Background A consensus of experts has proposed to replace the term nonalcoholic fatty liver disease (NAFLD), whose global prevalence is 25%, with metabolic…”
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Unravelling the health effects of fasting: a long road from obesity treatment to healthy life span increase and improved cognition by Wilhelmi de Toledo, Françoise, Grundler, Franziska, Sirtori, Cesare R., Ruscica, Massimiliano

“…In recent years a revival of interest has emerged in the health benefits of intermittent fasting and long-term fasting, as well as of other related nutritional…”
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Lipoprotein(a): Knowns, unknowns and uncertainties by Ruscica, Massimiliano, Sirtori, Cesare R., Corsini, Alberto, Watts, Gerald F., Sahebkar, Amirhossein

“…Over the last 10 years, there have been advances on several aspects of lipoprotein(a) which are reviewed in the present article. Since the standard…”
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Metformin: From diabetes to cancer to prolongation of life by Sirtori, Cesare R., Castiglione, Sofia, Pavanello, Chiara

“…The metformin molecule dates back to over a century, but its clinical use started in the ‘50s. Since then, its use in diabetics has grown constantly, with over…”
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PCSK9 Inhibition and Risk of Diabetes: Should We Worry? by Carugo, Stefano, Sirtori, Cesare R., Corsini, Alberto, Tokgozoglu, Lale, Ruscica, Massimiliano

“…Purpose of Review Since the clinical benefit of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors occurs in a setting of reducing low-density…”
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Lipid Lowering Drugs: Present Status and Future Developments by Ruscica, Massimiliano, Ferri, Nicola, Santos, Raul D., Sirtori, Cesare R., Corsini, Alberto

“…Purpose of review Based on the recent data of the DA VINCI study, it is clear that, besides utilization of statins, there is a need to increase non-statin…”
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Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9 by Ferri, Nicola, Ruscica, Massimiliano, Lupo, Maria Giovanna, Vicenzi, Marco, Sirtori, Cesare R., Corsini, Alberto

“…Immediate and aggressive lipid lowering therapies after acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI) are supported by the…”
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Present therapeutic role of cholesteryl ester transfer protein inhibitors by Ferri, Nicola, Corsini, Alberto, Sirtori, Cesare R., Ruscica, Massimiliano

“…[Display omitted] Therapeutic interventions aimed at increasing high-density lipoprotein (HDL) levels in order to reduce the residual cardiovascular (CV) risk…”
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Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia by Blom, Dirk J, Averna, Maurizio R, Meagher, Emma A, du Toit Theron, Hendrik, Sirtori, Cesare R, Hegele, Robert A, Shah, Prediman K, Gaudet, Daniel, Stefanutti, Claudia, Vigna, Giovanni B, Larrey, Dominique, Bloedon, LeAnne T, Foulds, Pamela, Rader, Daniel J, Cuchel, Marina

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