Search Results - "SIPILÄ, H"

Fibroblast state switching orchestrates dermal maturation and wound healing by Rognoni, Emanuel, Pisco, Angela Oliveira, Hiratsuka, Toru, Sipilä, Kalle H, Belmonte, Julio M, Mobasseri, Seyedeh Atefeh, Philippeos, Christina, Dilão, Rui, Watt, Fiona M

“…Murine dermis contains functionally and spatially distinct fibroblast lineages that cease to proliferate in early postnatal life. Here, we propose a model in…”
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Cardiac Positron Emission Tomography/Computed Tomography Imaging Accurately Detects Anatomically and Functionally Significant Coronary Artery Disease by KAJANDER, S, JOUTSINIEMI, E, HARTIALA, J, KNUUTI, J, SARASTE, M, PIETILÄ, M, UKKONEN, H, SARASTE, A, SIPILÄ, H. T, TERÄS, M, MÄKI, M, AIRAKSINEN, J

“…Computed tomography (CT) is increasingly used to detect coronary artery disease, but the evaluation of stenoses is often uncertain. Perfusion imaging has an…”
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Proline hydroxylation in collagen supports integrin binding by two distinct mechanisms by Sipilä, Kalle H., Drushinin, Kati, Rappu, Pekka, Jokinen, Johanna, Salminen, Tiina A., Salo, Antti M., Käpylä, Jarmo, Myllyharju, Johanna, Heino, Jyrki

“…Collagens are the most abundant extracellular matrix proteins in vertebrates and have a characteristic triple-helix structure. Hydroxylation of proline…”
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Joint inflammation related citrullination of functional arginines in extracellular proteins by Sipilä, Kalle H., Ranga, Vipin, Rappu, Pekka, Mali, Markku, Pirilä, Laura, Heino, Ilona, Jokinen, Johanna, Käpylä, Jarmo, Johnson, Mark S., Heino, Jyrki

“…We report the extent, specific sites and structural requirements of joint inflammation related citrullination in extracellular proteins. A total of 40 synovial…”
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Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage by Rognoni, Emanuel, Goss, Georgina, Hiratsuka, Toru, Sipilä, Kalle H, Kirk, Thomas, Kober, Katharina I, Lui, Prudence PokWai, Tsang, Victoria Sk, Hawkshaw, Nathan J, Pilkington, Suzanne M, Cho, Inchul, Ali, Niwa, Rhodes, Lesley E, Watt, Fiona M

“…Solar ultraviolet radiation (UVR) is a major source of skin damage, resulting in inflammation, premature ageing, and cancer. While several UVR-induced changes,…”
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Extracellular citrullination inhibits the function of matrix associated TGF-β by Sipilä, Kalle H., Ranga, Vipin, Rappu, Pekka, Torittu, Annamari, Pirilä, Laura, Käpylä, Jarmo, Johnson, Mark S., Larjava, Hannu, Heino, Jyrki

“…In inflammatory arthritis peptidyl arginine deiminase (PAD) enzymes can citrullinate arginine residues in extracellular matrix (ECM) proteins, such as…”
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Rosiglitazone but Not Metformin Enhances Insulin- and Exercise-Stimulated Skeletal Muscle Glucose Uptake in Patients With Newly Diagnosed Type 2 Diabetes by Hällsten, Kirsti, Virtanen, Kirsi A, Lönnqvist, Fredrik, Sipilä, Hannu, Oksanen, Airi, Viljanen, Tapio, Rönnemaa, Tapani, Viikari, Jorma, Knuuti, Juhani, Nuutila, Pirjo

“…Rosiglitazone but Not Metformin Enhances Insulin- and Exercise-Stimulated Skeletal Muscle Glucose Uptake in Patients With Newly Diagnosed Type 2 Diabetes…”
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Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control by Vietri Rudan, Matteo, Sipilä, Kalle H, Philippeos, Christina, Ganier, Clarisse, Bhosale, Priyanka G, Negri, Victor A, Watt, Fiona M

“…A fundamental challenge in molecular biology is to understand how evolving genomes can acquire new functions. Actively transcribed, non-coding parts of the…”
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An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis by Liakath-Ali, Kifayathullah, Mills, Eric W., Sequeira, Inês, Lichtenberger, Beate M., Pisco, Angela Oliveira, Sipilä, Kalle H., Mishra, Ajay, Yoshikawa, Harunori, Wu, Colin Chih-Chien, Ly, Tony, Lamond, Angus I., Adham, Ibrahim M., Green, Rachel, Watt, Fiona M.

“…Ribosome-associated mRNA quality control mechanisms ensure the fidelity of protein translation 1 , 2 . Although these mechanisms have been extensively studied…”
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The translating brain: cerebral activation patterns during simultaneous interpreting by Rinne, J.O, Tommola, J, Laine, M, Krause, B.J, Schmidt, D, Kaasinen, V, Teräs, M, Sipilä, H, Sunnari, M

“…Brain activation was measured in professional interpreters during simultaneous interpreting (SI) vs. repetition (shadowing) of auditorily presented text by…”
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Enhanced oxygen extraction and reduced flow heterogeneity in exercising muscle in endurance-trained men by Kalliokoski, K K, Oikonen, V, Takala, T O, Sipilä, H, Knuuti, J, Nuutila, P

“…The aim of this study was to investigate the effects of endurance training on skeletal muscle hemodynamics and oxygen consumption. Seven healthy…”
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Myocardial fatty acid oxidation in patients with impaired glucose tolerance by KNUUTI, J, TAKALA, T. O, NAGREN, K, SIPILÄ, H, TURPEINEN, A. K, UUSITUPA, M. I. J, NUUTILA, P

“…Fatty acids are an important source of energy in the myocardium. Abnormal myocardial fatty acid metabolism could contribute to the deterioration of cardiac…”
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Quantitative Blood Flow Measurement of Skeletal Muscle Using Oxygen-15-Water and PET by Ruotsalainen, Ulla, Raitakari, Maria, Nuutila, Pirjo, Oikonen, Vesa, Sipila, Hannu, Teras, Mika, Knuuti, M. Juhani, Bloomfield, Peter M, Iida, Hidehiro

“…The aim of the present study was to evaluate quantitation of muscle blood flow using [15O]H2O and PET. The autoradiographic (ARG) and the steady-state methods…”
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Estimation of optimal number of gates in dual gated 18F-FDG cardiac PET by Klén, R., Teuho, J., Noponen, T., Thielemans, K., Hoppela, E., Lehtonen, E., Sipila, H. T., Teräs, M., Knuuti, J.

“…Gating of positron emission tomography images has been shown to reduce the motion effects, especially when imaging small targets, such as coronary plaques…”
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Synchrotron X-ray topography study of defects in indium antimonide P-I-N structures grown by metal organic vapour phase epitaxy by RIIKONEN, J, TUOMI, T, SIPILÄ, H, VAIJÄRVI, S, LUMB, D, OWENS, A, LANKINEN, A, SORMUNEN, J, SÄYNÄTJOKI, A, KNUUTTILA, L, LIPSANEN, H, MCNALLY, P. J, O'REILLY, L, DANILEWSKY, A

“…InSb p-i-n structures were grown on an undoped InSb wafer in a horizontal metal organic vapour phase epitaxy reactor. 200 to 300 nm thick layers were…”
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Evidence for dissociation of insulin stimulation of blood flow and glucose uptake in human skeletal muscle: studies using [15O]H2O, [18F]fluoro-2-deoxy-D-glucose, and positron emission tomography by Raitakari, M., Nuutila, P., Ruotsalainen, U., Laine, H., Teras, M., Iida, H., Makimattila, S., Utriainen, T., Oikonen, V., Sipila, H., Haaparanta, M., Solin, O., Wegelius, U., Knuuti, J., Yki-Jarvinen, H.

“…Evidence for dissociation of insulin stimulation of blood flow and glucose uptake in human skeletal muscle: studies using [15O]H2O,…”
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Low radiation dose imaging of myocardial perfusion and coronary angiography with a hybrid PET/CT scanner by Kajander, S., Ukkonen, H., Sipilä, H., Teräs, M., Knuuti, J.

“…Summary Objectives:  To test the image quality and feasibility of a sequential low radiation dose protocol for hybrid cardiac PET/CT angiography (CTA)…”
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Insulin increases blood volume in human skeletal muscle: studies using [15O]CO and positron emission tomography by Raitakari, M, Knuuti, M J, Ruotsalainen, U, Laine, H, Mäkeä, P, Teräs, M, Sipilä, H, Niskanen, T, Raitakari, O T, Iida, H, Härkönen, R, Wegelius, U, Yki-Järvinen, H, Nuutila, P

“…High insulin concentrations increase blood flow in the leg, but it is unknown whether this effect is associated with a change in muscle blood volume. In the…”
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Technology development for soft X-ray spectroscopy by Törmä, P.T., Sipilä, H.J., Koskinen, T., Mattila, M.

“…X-ray spectroscopy instruments lose part of their performance due to the lack of suitable components for soft X-ray region below 1keV. Therefore, in the…”
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Feasibility of conversion electron spectrometry using a Peltier-cooled silicon drift detector by Peräjärvi, K., Turunen, J., Ihantola, S., Kämäräinen, V., Pommé, S., Pöllänen, R., Siiskonen, T., Sipilä, H., Toivonen, H.

“…A Peltier-cooled silicon drift detector was successfully applied for conversion electron spectrometry. The energy resolution of the detector for 45 keV…”
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