Search Results - "SIPES, I. G"

RIFM fragrance ingredient safety assessment, acetyl cedrene, CAS Registry Number 32388-55-9 by Api, A.M., Belsito, D., Botelho, D., Bruze, M., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Date, M., Dekant, W., Deodhar, C., Fryer, A.D., Jones, L., Joshi, K., Kumar, M., Lapczynski, A., Lavelle, M., Lee, I., Liebler, D.C., Moustakas, H., Na, M., Penning, T.M., Ritacco, G., Romine, J., Sadekar, N., Schultz, T.W., Selechnik, D., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Acetyl cedrene; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Prediction of Metabolic Clearance of Bisphenol A (4,4 ′-Dihydroxy-2,2-diphenylpropane) using Cryopreserved Human Hepatocytes by KUESTER, R. K, SIPES, I. G

“…This study investigated the kinetics of glucuronidation of bisphenol A (BPA; 4,4′-dihydroxy-2,2-diphenylpropane) in cryopreserved human hepatocytes (HCs)…”
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A toxicologic and dermatologic assessment of cinnamyl alcohol, cinnamaldehyde and cinnamic acid when used as fragrance ingredients by Bickers, D., Calow, P., Greim, H., Hanifin, J.M., Rogers, A.E., Saurat, J.H., Sipes, I.G., Smith, R.L., Tagami, H.

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Metabolism of Bisphenol A in Primary Cultured Hepatocytes from Mice, Rats, and Humans by PRITCHETT, J. J, KUESTER, R. K, SIPES, I. G

“…Studies have shown that in the rat, bisphenol A (BPA) is metabolized and eliminated primarily as a monoglucuronide, a metabolite without estrogenic activity…”
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Safety assessment of allylalkoxybenzene derivatives used as flavouring substances — methyl eugenol and estragole by Smith, R.L, Adams, T.B, Doull, J, Feron, V.J, Goodman, J.I, Marnett, L.J, Portoghese, P.S, Waddell, W.J, Wagner, B.M, Rogers, A.E, Caldwell, J, Sipes, I.G

“…This publication is the seventh in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers' Association (FEMA). In…”
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The Effects of Dose and Route on the Toxicokinetics and Disposition of 1-Butyl-3-methylimidazolium Chloride in Male F-344 Rats and Female B6C3F1 Mice by SIPES, I. G, KNUDSEN, G. A, KUESTER, R. K

“…These studies characterize the effect of dose and route of administration on the disposition and elimination of the ionic liquid, 1-butyl-3-methylimidazolium…”
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Characterization of the Disposition and Toxicokinetics of N-Butylpyridinium Chloride in Male F-344 Rats and Female B6C3F1 Mice and Its Transport by Organic Cation Transporter 2 by CHENG, Y, WRIGHT, S. H, HOOTH, M. J, SIPES, I. G

“…Studies were conducted to characterize the effect of dose and route of administration on the disposition of N -butylpyridinium chloride (NBuPy-Cl), an ionic…”
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Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients by Api, A.M., Belsito, D., Bruze, M., Cadby, P., Calow, P., Dagli, M.L., Dekant, W., Ellis, G., Fryer, A.D., Fukayama, M., Griem, P., Hickey, C., Kromidas, L., Lalko, J.F., Liebler, D.C., Miyachi, Y., Politano, V.T., Renskers, K., Ritacco, G., Salvito, D., Schultz, T.W., Sipes, I.G., Smith, B., Vitale, D., Wilcox, D.K.

“…•This publication is designed to update the RIFM safety assessment process, which follows a series of decision trees.•This process incorporates advances in…”
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Ovotoxicity in Female Fischer Rats and B6 Mice Induced by Low-Dose Exposure to Three Polycyclic Aromatic Hydrocarbons: Comparison through Calculation of an Ovotoxic Index by Borman, S.M., Christian, P.J., Sipes, I.G., Hoyer, P.B.

“…Extensive destruction of primordial follicles by exposure to ovarian toxicants can cause early menopause in women. Primordial follicle destruction is known to…”
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Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats by KNUDSEN, G. A, CHENG, Y, KUESTER, R. K, HOOTH, M. J, SIPES, I. G

“…Studies were conducted to characterize the effects of dose and route of administration on the disposition of 1-butyl-1-methylpyrrolidinium (BmPy-Cl) in male…”
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Absorption, distribution, metabolism and excretion of intravenously and orally administered tetrabromobisphenol A [2,3-dibromopropyl ether] in male Fischer-344 rats by Knudsen, G.A, Jacobs, L.M, Kuester, R.K, Sipes, I.G

“…Abstract Tetrabromobisphenol A bis[2,3-dibromopropyl ether],2,2-bis[3,5-dibromo-4-(2,3-dibromopropoxy)phenyl]propane is a brominated flame retardant with…”
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A toxicologic and dermatologic assessment of linalool and related esters when used as fragrance ingredients by Bickers, D, Calow, P, Greim, H, Hanifin, J.M, Rogers, A.E, Saurat, J.H, Sipes, I.G, Smith, R.L, Tagami, H

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Update to RIFM fragrance ingredient safety assessment, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl pivalate, CAS Registry Number 68039-45-2 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•3a,4,5,6,7,7a-Hexahydro-4,7-methano-1H-inden-5-yl pivalate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health…”
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Update to RIFM fragrance ingredient safety assessment, (Z)-octadec-9-enol, CAS registry number 143-28-2 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•(Z)-Octadec-9-enol; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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RIFM fragrance ingredient safety assessment, allyl α-ionone, CAS Registry Number 79-78-7 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Allyl α-ionone; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, oxacyclohexadecane-2,13-dione, CAS registry number 38223-29-9 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Oxacyclohexadecane-2,13-dione; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All…”
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Update to RIFM fragrance ingredient safety assessment, isobornyl propionate, CAS Registry Number 2756-56-1 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Isobornyl propionate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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RIFM fragrance ingredient safety assessment, allyl hexanoate, CAS Registry Number 123-68-2 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Allyl hexanoate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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RIFM fragrance ingredient safety assessment, phenethyl alcohol, CAS Registry Number 60-12-8 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Phenethyl alcohol; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were…”
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Update to RIFM fragrance ingredient safety assessment, tricyclodecanyl acetate, CAS registry number 64001-15-6 by Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.

“…•Tricyclodecanyl acetate; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints…”
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