Search Results - "SINGH, Rana P"

EGFR-mediated Rad51 expression potentiates intrinsic resistance in prostate cancer via EMT and DNA repair pathways by Rajput, Mohit, Singh, Ragini, Singh, Navneendra, Singh, Rana P.

“…To study the role of EGFR signaling in regulation of intrinsic resistance in prostate cancer. Radioresistant prostate carcinoma DU145 and PC-3 cells were used…”
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Acacetin enhances the therapeutic efficacy of doxorubicin in non-small-cell lung carcinoma cells by Punia, Reenu, Raina, Komal, Agarwal, Rajesh, Singh, Rana P

“…Anthracyclines are efficient and potent agents to treat broad range of cancers but cytotoxicity induced by them limits their use in therapeutics. Use of…”
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Fisetin inhibits cellular proliferation and induces mitochondria‐dependent apoptosis in human gastric cancer cells by Sabarwal, Akash, Agarwal, Rajesh, Singh, Rana P.

“…The anticancer effects of fisetin, a dietary agent, are largely unknown against human gastric cancer. Herein, we investigated the mechanisms of fisetin‐induced…”
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Targeting DNA repair for cancer treatment: Lessons from PARP inhibitor trials by Nambiar, Dhanya K, Mishra, Deepali, Singh, Rana P

“…Ionizing radiation is frequently used to treat solid tumors, as it causes DNA damage and kill cancer cells. However, damaged DNA is repaired involving…”
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Tension pneumocephalus in a patient with NF1 following ventriculoperitoneal shunt—deciphering the cause and proposed management strategy by Singh, Kavindra, Kumar, Ashutosh, Srivastava, Arun, Singh, Rana P., Kumar, Raj

“…Introduction Spontaneous pneumocephalus following ventriculoperitoneal shunting is a very unique complication, seen in a handful of patients. Small bony…”
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An assessment of poly (ADP‐ribose) polymerase‐1 role in normal and cancer cells by Kumar, Manoj, Jaiswal, Rishi Kumar, Yadava, Pramod K., Singh, Rana P.

“…Poly (ADP‐ribose) polymerase (PARP) is a superfamily of 18 proteins characterized by the PARP homology domain, the catalytic domain. This catalytic domain…”
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Therapeutic application of Carica papaya leaf extract in the management of human diseases by Singh, Surya P., Kumar, Sanjay, Mathan, Sivapar V., Tomar, Munendra Singh, Singh, Rishi Kant, Verma, Praveen Kumar, Kumar, Amit, Kumar, Sandeep, Singh, Rana P., Acharya, Arbind

“…Introduction Papaya ( Carica papaya Linn.) belongs to the family Caricaceae and is well known for its therapeutic and nutritional properties all over the…”
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Therapeutic potential of biogenic and optimized silver nanoparticles using Rubia cordifolia L. leaf extract by Chandraker, Sandip Kumar, Lal, Mishri, Khanam, Farheen, Dhruve, Preeti, Singh, Rana P., Shukla, Ravindra

“…Rubia cordifolia L. is a widely used traditional medicine in the Indian sub-continent and Eastern Asia. In the present study, the aqueous leaf extract of the…”
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Genetically engineered bacteria: An emerging tool for environmental remediation and future research perspectives by Singh, Jay Shankar, Abhilash, P.C., Singh, H.B., Singh, Rana P., Singh, D.P.

“…This minireview explores the environmental bioremediation mediated by genetically engineered (GE) bacteria and it also highlights the limitations and…”
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Silibinin Inhibits Colorectal Cancer Growth by Inhibiting Tumor Cell Proliferation and Angiogenesis by SINGH, Rana P, GU, Mallikarjuna, AGARWAL, Rajesh

“…Herein, for the first time, we investigated in vivo efficacy and associated molecular biomarkers and mechanisms of a chemopreventive agent, silibinin, against…”
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Arsenic hazards in coal fly ash and its fate in Indian scenario by Pandey, Vimal Chandra, Singh, Jay Shankar, Singh, Rana P., Singh, Nandita, Yunus, M.

“…Fly ash (FA) generated as a waste produced from thermal power plants globally has started gaining as a potentially significant anthropogenic source of arsenic…”
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Meeting report: International Symposium on Mitochondria, Cell Death and Human Diseases: Jawaharlal Nehru University, New Delhi, India, February 18-19, 2023 by Singh, Rana P, Birge, Raymond B, Chandra, Dhyan

“…The School of Life Sciences at the Jawaharlal Nehru University in New Delhi, India held an International Symposium on Mitochondria, Cell Death and Human…”
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Silibinin Inhibits Established Prostate Tumor Growth, Progression, Invasion, and Metastasis and Suppresses Tumor Angiogenesis and Epithelial-Mesenchymal Transition in Transgenic Adenocarcinoma of the Mouse Prostate Model Mice by SINGH, Rana P, RAINA, Komal, SHARMA, Girish, AGARWAL, Rajesh

“…Purpose: The chronic nature of prostate cancer growth and progression leading to metastasis provides a large window for intervention. Herein, for the first…”
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Induction of endothelial dysfunction by oxidized low-density lipoproteins via downregulation of Erk-5/Mef2c/KLF2 signaling: Amelioration by fisetin by Patel, Rohit, Varghese, Johnna F., Singh, Rana P., Yadav, Umesh C.S.

“…Extra-cellular signal regulated kinase-5 (Erk-5), a transcriptional activator and regulator of endothelial cells (ECs) homeostasis, has been implicated in…”
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Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy by Nambiar, Dhanya, Rajamani, Paulraj, Singh, Rana P.

“…Ionizing radiation (IR)-induced cellular damage is implicated in carcinogenesis as well as therapy of cancer. Advances in radiation therapy have led to the…”
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Tillage Effects on Crop Yield and Physicochemical Properties of Sodic Soils by Singh, Kripal, Mishra, Ashish Kumar, Singh, Bajrang, Singh, Rana P, Patra, Dharani Dhar

“…Tillage modifies soil structure and has been suggested as a practice to improve physical, hydrological and chemical properties of compacted soils. But little…”
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Oncogenic potential of SARS-CoV-2-targeting hallmarks of cancer pathways by Jaiswal, Aishwarya, Shrivastav, Sanah, Kushwaha, Hemant R, Chaturvedi, Rupesh, Singh, Rana P

“…The 2019 outbreak of SARS-CoV-2 has caused a major worldwide health crisis with high rates of morbidity and death. Interestingly, it has also been linked to…”
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Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation by Schlaepfer, Isabel R, Nambiar, Dhanya K, Ramteke, Anand, Kumar, Rahul, Dhar, Deepanshi, Agarwal, Chapla, Bergman, Bryan, Graner, Michael, Maroni, Paul, Singh, Rana P, Agarwal, Rajesh, Deep, Gagan

“…Hypoxia is an independent prognostic indicator of poor outcome in several malignancies. However, precise mechanism through which hypoxia promotes disease…”
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Cytotoxic, Antimitotic, DNA Binding, Photocatalytic, H2O2 Sensing, and Antioxidant Properties of Biofabricated Silver Nanoparticles Using Leaf Extract of Bryophyllum pinnatum (Lam.) Oken by Chandraker, Sandip Kumar, Lal, Mishri, Dhruve, Preeti, Singh, Rana P., Shukla, Ravindra

“…Bryophyllum pinnatum is a perennial herb traditionally used in ethnomedicine. In the present report, silver nanoparticles (AgNPs) were synthesized using B…”
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Rhizoremediation potential of spontaneously grown Typha latifolia on fly ash basins: Study from the field by Pandey, Vimal Chandra, Singh, Nandita, Singh, Rana P., Singh, D.P.

“…•Increasing fly ash (FA) disposal area is worldwide problem.•Spontaneously growing plant species is a potential asset for the remediation of FA.•Flooded Typha…”
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