Search Results - "SINGH, Nirmal"
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1
Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy
Published in Toxicology (Amsterdam) (27-01-2012)“…Abstract Anti-cancer drugs such as vincristine, paclitaxel, oxaliplatin, cisplatin and bortezomib are well reported to exert direct and indirect effects on…”
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2
Advanced glycation end products and diabetic complications
Published in The Korean journal of physiology & pharmacology (01-02-2014)“…During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known…”
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3
Role of different brain areas in peripheral nerve injury-induced neuropathic pain
Published in Brain research (24-03-2011)“…Abstract Neuropathic pain has been described as the “most terrible of all tortures which a nerve wound may inflict” and arises as a consequence of nerve injury…”
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4
A review on chemical-induced inflammatory bowel disease models in rodents
Published in The Korean journal of physiology & pharmacology (01-08-2014)“…Ulcerative colitis and Crohn's disease are a set of chronic, idiopathic, immunological and relapsing inflammatory disorders of the gastrointestinal tract…”
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5
A systematic comparison of human mitochondrial genome assembly tools
Published in BMC bioinformatics (13-09-2023)“…Mitochondria are the cell organelles that produce most of the chemical energy required to power the cell's biochemical reactions. Despite being a part of a…”
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6
Histone acetylation and histone deacetylation in neuropathic pain: An unresolved puzzle?
Published in European journal of pharmacology (15-01-2017)“…Chronic pain is broadly classified into somatic, visceral or neuropathic pain depending upon the location and extent of pain perception. Evidences from…”
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7
Exploration of multi-target potential of chromen-4-one based compounds in Alzheimer’s disease: Design, synthesis and biological evaluations
Published in Bioorganic & medicinal chemistry (15-12-2017)“…A novel series of flavonoid based compounds were designed, synthesized and biologically evaluated for Acetylcholinesterase (AChE) inhibitory activity…”
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8
Implications and mechanism of action of gabapentin in neuropathic pain
Published in Archives of pharmacal research (01-03-2013)“…Gabapentin is an anti-epileptic agent but now it is also recommended as first line agent in neuropathic pain, particularly in diabetic neuropathy and post…”
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9
Optimization and ecofriendly synthesis of iron oxide nanoparticles as potential antioxidant
Published in Arabian journal of chemistry (01-12-2020)“…The present study involves the use of Box-Behnken design for optimization of the energy-efficient process variables, eco-friendly synthesis of nanoparticles of…”
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10
Pharmacological activation of protein kinase A improves memory loss and neuropathological changes in a mouse model of dementia of Alzheimer’s type
Published in Behavioural pharmacology (01-04-2017)“…The study investigates the therapeutic potential of the protein kinase A (PKA) activator forskolin in cognitive deficits of mice. Streptozotocin (STZ) [3…”
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11
A Novel Approach for Detection of Hard Exudates Using Random Forest Classifier
Published in Journal of medical systems (01-07-2019)“…Diabetic Retinopathy is the major cause of blindness for diabetics in which the retina is damaged. Regular screening system help in detecting the early…”
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12
Pharmacological inhibition of inducible nitric oxide synthase (iNOS) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, convalesce behavior and biochemistry of hypertension induced vascular dementia in rats
Published in Pharmacology, biochemistry and behavior (01-02-2013)“…Cognitive disorders are likely to increase over the coming years (5–10). Vascular dementia (VaD) has heterogeneous pathology and is a challenge for clinicians…”
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13
Identification and Detection of Bioactive Peptides in Milk and Dairy Products: Remarks about Agro-Foods
Published in Molecules (Basel, Switzerland) (22-07-2020)“…Food-based components represent major sources of functional bioactive compounds. Milk is a rich source of multiple bioactive peptides that not only help to…”
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14
Attenuation of neuropathic pain by sodium butyrate in an experimental model of chronic constriction injury in rats
Published in Journal of the Formosan Medical Association (01-12-2014)“…Background/Purpose The present study was designed to investigate the potential of sodium butyrate, a histone deacetylase (HDAC) inhibitor, in chronic…”
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15
Nano-enhanced storage of American cotton using metal-oxide nanoparticles for improving seed quality traits
Published in Scientific reports (18-10-2024)“…Cotton seeds have poorer germination than other crops because of their high sensitivity towards insect pests and other biotic and abiotic stresses during the…”
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16
Pregabalin in Neuropathic Pain: Evidences and Possible Mechanisms
Published in Current neuropharmacology (01-01-2014)“…Pregabalin is an antagonist of voltage gated Ca 2+ channels and specifically binds to alpha-2-delta subunit to produce antiepileptic and analgesic actions. It…”
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17
Ameliorative Effect of Phosphodiesterase-5 Inhibitor in Rat Model of Vascular Dementia
Published in Current neurovascular research (01-01-2019)“…Cerebral hypoperfusion has been considered as major risk factor for Vascular Dementia (VaD). The present study shows the potential of Tadalafil, a…”
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18
Biostimulant-Treated Seedlings under Sustainable Agriculture: A Global Perspective Facing Climate Change
Published in Agronomy (Basel) (01-01-2021)“…The primary objectives of modern agriculture includes the environmental sustainability, low production costs, improved plants’ resilience to various biotic and…”
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Exploring the potential of telmisartan in chronic constriction injury-induced neuropathic pain in rats
Published in European journal of pharmacology (30-09-2011)“…The present study was designed to investigate the potential of telmisartan, an angiotensin AT 1 receptor, in chronic constriction injury-induced neuropathic…”
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20
Splicing of a Critical Exon of Human Survival Motor Neuron Is Regulated by a Unique Silencer Element Located in the Last Intron
Published in Molecular and Cellular Biology (01-02-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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