Search Results - "SINGH, Kumud K"

Human Bocavirus: Prevalence and Clinical Spectrum at a Children's Hospital by Arnold, John C., Singh, Kumud K., Spector, Stephen A., Sawyer, Mark H.

“…Background. Molecular methods of pathogen discovery have recently led to the description of several new respiratory viruses. Human bocavirus (HBoV), a proposed…”
Get full text

Killer Cell Immunoglobulin-Like Receptor Alleles Alter HIV Disease in Children by Singh, Kumud K, Qin, Min, Brummel, Sean S, Angelidou, Konstantia, Trout, Rodney N, Fenton, Terence, Spector, Stephen A

“…HLA class I molecules are ligands for killer cell immunoglobin like receptors (KIR) that control the antiviral response of natural killer (NK) cells. However,…”
Get full text

Human Immunodeficiency Virus Type 1 Subtype C Tat Fails To Induce Intracellular Calcium Flux and Induces Reduced Tumor Necrosis Factor Production from Monocytes by CAMPBELL, Grant R, WATKINS, Jennifer D, SINGH, Kumud K, LORET, Erwann P, SPECTOR, Stephen A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1–related disease in children by Singh, Kumud K., PhD, Lieser, Alexis, MD, Ruan, Ping K., PhD, Fenton, Terry, EdD, Spector, Stephen A., MD

“…Background Mannose-binding lectin (MBL) is part of the lectin pathway of complement activation against various pathogens; however, its role in innate immune…”
Get full text

The influence of HLA on HIV-associated neurocognitive impairment in Anhui, China by Schrier, Rachel D, Gupta, Saurabh, Riggs, Patricia, Cysique, Lucette A, Letendre, Scott, Jin, Hua, Spector, Stephen A, Singh, Kumud K, Wolfson, Tanya, Wu, Zunyou, Hong, Kun Xue, Yu, Xin, Shi, Chuan, Heaton, Robert K

“…HLA-DR*04 was identified as a predictor of HIV-Associated neurocognitive disorder (HAND), low CD4 T-cell responses to HIV, and low plasma HIV RNA levels in a…”
Get full text

Genetic Variants in Toll-Like Receptor 2 (TLR2), TLR4, TLR9, and FCγ Receptor II Are Associated with Antibody Response to Quadrivalent Meningococcal Conjugate Vaccine in HIV-Infected Youth by Spector, Stephen A, Qin, Min, Lujan-Zilbermann, Jorge, Singh, Kumud K, Warshaw, Meredith G, Williams, Paige L, Jean-Philippe, Patrick, Fenton, Terence, Siberry, George K

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Genetic Influence of CCR5, CCR2 and SDF1 Variants on Human Immunodeficiency Virus 1 (HIV-1)–Related Disease Progression and Neurological Impairment, in Children with Symptomatic HIV-1 Infection by Singh, Kumud K., Barroga, Charlene F., Hughes, Michael D., Chen, Jie, Raskino, Claire, McKinney, Ross E., Spector, Stephen A.

“…The role that host genetics plays in the modification of the rate of human immunodeficiency virus 1 (HIV-1)–related disease progression was evaluated in a…”
Get full text

Genomics Links Inflammation With Neurocognitive Impairment in Children Living With Human Immunodeficiency Virus Type-1 by Rawat, Pratima, Brummel, Sean S, Singh, Kumud K, Kim, Jihoon, Frazer, Kelly A, Nichols, Sharon, Seage, George R, Williams, Paige L, Van Dyke, Russell B, Harismendy, Olivier, Trout, Rodney N, Spector, Stephen A

“…Abstract Background We identified host single-nucleotide variants (SNVs) associated with neurocognitive impairment (NCI) in perinatally HIV-infected (PHIV)…”
Get full text

Longevity of lobsters is linked to ubiquitous telomerase expression by Klapper, Wolfram, Kühne, Karen, Singh, Kumud K, Heidorn, Klaus, Parwaresch, Reza, Krupp, Guido

“…Mammals have high growth rates in embryonic and juvenile phases and no growth in adult and senescent phases. We analyzed telomerase activity in a fundamentally…”
Get full text

Vitamin D–related Host Genetic Variants Alter HIV Disease Progression in Children by Moodley, Amaran, Qin, Min, Singh, Kumud K, Spector, Stephen A

“…BACKGROUND:Vitamin D deficiency is common in HIV infection and has been associated with advanced disease. This study investigated whether vitamin D–related…”
Get full text

Genetic Variants in the Host Restriction Factor APOBEC3G are Associated With HIV-1–Related Disease Progression and Central Nervous System Impairment in Children by Singh, Kumud K, Wang, Yan, Gray, Kathryn P, Farhad, Mona, Brummel, Sean, Fenton, Terence, Trout, Rodney, Spector, Stephen A

“…BACKGROUND:Apolipoprotein B mRNA editing catalytic polypeptide 3G (APOBEC3G) protein is incorporated into nascent virus particles and mediates cytidine…”
Get full text

Host Genetic Determinants of Human Immunodeficiency Virus Infection and Disease Progression in Children by Singh, Kumud K, Spector, Stephen A

“…Increasing data support host genetic factors as an important determinants of human immunodeficiency virus type-1 (HIV-1) susceptibility, mother-to-child…”
Get full text

Genetically determined ancestry is more informative than self-reported race in HIV-infected and -exposed children by Spector, Stephen A., Brummel, Sean S., Nievergelt, Caroline M., Maihofer, Adam X., Singh, Kumud K., Purswani, Murli U., Williams, Paige L., Hazra, Rohan, Van Dyke, Russell, Seage, George R.

“…The Pediatric HIV/AIDS Cohort Study (PHACS), the largest ongoing longitudinal study of perinatal HIV-infected (PHIV) and HIV-exposed, uninfected (PHEU)…”
Get full text

Associations of Host Genetic Variants on CD4+ Lymphocyte Count and Plasma HIV-1 RNA in Antiretroviral Naïve Children by MIN QIN, BRUMMEL, Sean, SINGH, Kumud K, FENTON, Terence, SPECTOR, Stephen A

“…CD4 T-lymphocyte (CD4) counts and HIV plasma RNA concentration (RNA) are 2 key HIV disease markers. The complex interplay between virus and host genetics may…”
Get full text

Lack of Protective Effects of Interleukin-4 −589-C/T Polymorphism against HIV-1-Related Disease Progression and Central Nervous System Impairment, in Children by Singh, Kumud K., Hughes, Michael D., Chen, Jie, Spector, Stephen A.

“…The interleukin (IL)-4 −589-C/T polymorphism has been reported to protect against human immunodeficiency virus type 1 (HIV-1)-related disease progression in…”
Get full text

Human Metapneumovirus Associated With Central Nervous System Infection in Children by ARNOLD, John C, SINGH, Kumud K, MILDER, Edmund, SPECTOR, Stephen A, SAWYER, Mark H, GAVALI, Shilpa, GLASER, Carol

“…Human metapneumovirus (hMPV) is an established pathogen of the respiratory tract of children and adults. hMPV is related to other paramyxoviruses known to…”
Get full text

Associations of Genetically Determined Continental Ancestry With CD4+ Count and Plasma HIV-1 RNA Beyond Self-Reported Race and Ethnicity by Brummel, Sean S, Singh, Kumud K, Maihofer, Adam X, Farhad, Mona, Qin, Min, Fenton, Terry, Nievergelt, Caroline M, Spector, Stephen A

“…BACKGROUND:Ancestry informative markers (AIMs) measure genetic admixtures within an individual beyond self-reported racial/ethnic (SRR) groups. Here, we used…”
Get full text

Complement Component 3 Is Associated with Metabolic Comorbidities in Older HIV-Positive Adults by Bryant, Alex K, Fazeli, Pariya L, Letendre, Scott L, Ellis, Ronald J, Potter, Michael, Burdo, Tricia H, Singh, Kumud K, Jeste, Dilip V, Grant, Igor, Moore, David J

“…Our objective was to evaluate the association of plasma inflammatory biomarkers with MetS in an older population of treated HIV-infected (HIV(+)) as compared…”
Get more information

Mannose binding lectin mediated complement pathway in multiple sclerosis by Kwok, Janet Y, Vaida, Florin, Augst, Ryan M, Yu, Denise Y, Singh, Kumud K

“…Abstract Role of mannose binding lectin (MBL) complement activation pathway, an arm of innate immunity in multiple sclerosis (MS) was evaluated by analyzing…”
Get full text

Undiagnosed Respiratory Viruses in Children by Arnold, John C, Singh, Kumud K, Spector, Stephen A, Sawyer, Mark H

“…An estimated 12 to 32 million upper respiratory infections occur in young children each year. In addition, 20% to 53% of infants will have > or = 1 episode of…”
Get full text