Search Results - "SINGER, R. H"

Mitochondria-associated yeast mRNAs and the biogenesis of molecular complexes by Garcia, M, Darzacq, X, Delaveau, T, Jourdren, L, Singer, R H, Jacq, C

“…The coherence of mitochondrial biogenesis relies on spatiotemporally coordinated associations of 800-1000 proteins mostly encoded in the nuclear genome. We…”
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Single mRNA Molecules Demonstrate Probabilistic Movement in Living Mammalian Cells by Fusco, Dahlene, Accornero, Nathalie, Lavoie, Brigitte, Shenoy, Shailesh M., Blanchard, Jean-Marie, Singer, Robert H., Bertrand, Edouard

“…Cytoplasmic mRNA movements ultimately determine the spatial distribution of protein synthesis. Although some mRNAs are compartmentalized in cytoplasmic…”
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role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation by Vainer, G, Vainer-Mosse, E, Pikarsky, A, Shenoy, SM, Oberman, F, Yeffet, A, Singer, RH, Pikarsky, E, Yisraeli, JK

“…VICKZ proteins are a highly conserved family of RNA binding proteins, implicated in RNA regulatory processes such as intracellular RNA localization, RNA…”
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Visualization of Single RNA Transcripts in Situ by Femino, Andrea M., Fay, Fredric S., Fogarty, Kevin, Singer, Robert H.

“…Fluorescence in situ hybridization (FISH) and digital imaging microscopy were modified to allow detection of single RNA molecules. Oligodeoxynucleotide probes…”
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Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions by Chicurel, M. E., Singer, R. H., Meyer, C. J., Ingber, D. E.

“…The extracellular matrix (ECM) activates signalling pathways that control cell behaviour by binding to cell-surface integrin receptors and inducing the…”
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Neurotrophin-Induced Transport of a β-Actin mRNP Complex Increases β-Actin Levels and Stimulates Growth Cone Motility by Zhang, H.L., Eom, T., Oleynikov, Y., Shenoy, S.M., Liebelt, D.A., Dictenberg, J.B., Singer, R.H., Bassell, G.J.

“…Neurotrophin regulation of actin-dependent changes in growth cone motility may depend on the signaling of β-actin mRNA transport. Formation of an RNP complex…”
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The Physiological Significance of β-actin mRNA Localization in Determining Cell Polarity and Directional Motility by Shestakova, Elena A., Singer, Robert H., Condeelis, John

“…β-actin mRNA is localized near the leading edge in several cell types, where actin polymerization is actively promoting forward protrusion. The localization of…”
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Characterization of a beta-actin mRNA zipcode-binding protein by Ross, Anthony F., Oleynikov, Yuri, Kislauskis, Edward H., Taneja, Krishan L., Singer, Robert H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Neurotrophin Regulation of β-Actin mRNA and Protein Localization within Growth Cones by Zhang, H. L., Singer, R. H., Bassell, G. J.

“…Neurotrophins play an essential role in the regulation of actin-dependent changes in growth cone shape and motility. We have studied whether neurotrophin…”
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Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA by Long, R.M. (Albert Einstein College of Medicine, Bronx, NY.), Singer, R.H, Meng, X, Gonzalez, I, Nasmyth, K, Jansen, R.P

“…Cell divisions that produce progeny differing in their patterns of gene expression are key to the development of multicellular organisms. In the budding yeast…”
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The travels of mRNAs through all cells large and small by Bassell, G. J., Oleynikov, Y., Singer, R. H.

“…THE DETERMINATION OF ASYMMETRY is one of the most important events in cell differentiation and development. Cellular asymmetry in many cases is essential for…”
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Sequences Responsible for Intracellular Localization of β-Actin Messenger RNA Also Affect Cell Phenotype by Kislauskis, Edward H., Zhu, Xiaochun, Singer, Robert H.

“…We have characterized the structure and function of RNA sequences that direct β-cytoplasmic actin mRNA to the cell periphery were mapped to two segments of…”
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Foci of Trinucleotide Repeat Transcripts in Nuclei of Myotonic Dystrophy Cells and Tissues by Taneja, Krishan L., McCurrach, Mila, Schalling, Martin, Housman, David, Singer, Robert H.

“…We have analyzed the intracellular localization of transcripts from the myotonin protein kinase (Mt-PK) gene in fibroblasts and muscle biopsies from myotonic…”
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Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo by Chartrand, P., Meng, X-H., Singer, R.H., Long, R.M.

“…The sorting of the Ash1 protein to the daughter nucleus of Saccharomyces cerevisiae in late anaphase of the budding cycle correlates with the localization of…”
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Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells by Politz, Joan C., Tuft, Richard A., Pederson, Thoru, Singer, Robert H.

“…Background: Messenger RNA (mRNA) is transcribed and processed in the nucleus of eucaryotic cells and then exported to the cytoplasm through nuclear pores. It…”
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Chronic Periodontitis Genome-wide Association Study in the Hispanic Community Health Study / Study of Latinos by Sanders, A.E., Sofer, T., Wong, Q., Kerr, K.F., Agler, C., Shaffer, J.R., Beck, J.D., Offenbacher, S., Salazar, C.R., North, K.E., Marazita, M.L., Laurie, C.C., Singer, R.H., Cai, J., Finlayson, T.L., Divaris, K.

“…Chronic periodontitis (CP) has a genetic component, particularly its severe forms. Evidence from genome-wide association studies (GWASs) has highlighted…”
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RNP LOCALIZATION AND TRANSPORT IN YEAST by Chartrand, Pascal, Singer, Robert H, Long, Roy M

“…The localization of mRNAs is used by various types of polarized cells to locally translate specific proteins, which restricts their distribution to a…”
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Transcriptional Pulsing of a Developmental Gene by Chubb, Jonathan R., Trcek, Tatjana, Shenoy, Shailesh M., Singer, Robert H.

“…It has not been possible to view the transcriptional activity of a single gene within a living eukaryotic cell. It is therefore unclear how long and how…”
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The odyssey of a regulated transcript by VILARDELL, JOSEP, CHARTRAND, PASCAL, SINGER, ROBERT H., WARNER, JONATHAN R.

“…The transcript of the Saccharomyces cerevisiae gene, RPL30, is subject to regulated splicing and regulated translation, due to a structure that interacts with…”
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Isoform-Specific 3′-Untranslated Sequences Sort α-Cardiac and β-Cytoplasmic Actin Messenger RNAs to Different Cytoplasmic Compartments by Kislauskis, Edward H., Li, Zhifang, Singer, Robert H., Taneja, Krishan L.

“…We demonstrate that in differentiating myoblasts, the mRNAs encoding two actin isoforms, β-cytoplasmic, and α-cardiac, can occupy different cytoplasmic…”
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