Search Results - "SINGER, JOEL"

Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols by Park, Jay J H, Siden, Ellie, Zoratti, Michael J, Dron, Louis, Harari, Ofir, Singer, Joel, Lester, Richard T, Thorlund, Kristian, Mills, Edward J

“…Master protocols, classified as basket trials, umbrella trials, and platform trials, are novel designs that investigate multiple hypotheses through concurrent…”
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Arterial stiffness, the brain and cognition: A systematic review by Singer, Joel, Trollor, Julian N, Baune, Bernhard T, Sachdev, Perminder S, Smith, Evelyn

“…Highlights • Arterial stiffness is associated with markers of cerebral small vessel disease. • Arterial stiffness is also associated with decreased cognitive…”
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Less-Tight versus Tight Control of Hypertension in Pregnancy by Magee, Laura A, von Dadelszen, Peter, Rey, Evelyne, Ross, Susan, Asztalos, Elizabeth, Murphy, Kellie E, Menzies, Jennifer, Sanchez, Johanna, Singer, Joel, Gafni, Amiram, Gruslin, Andrée, Helewa, Michael, Hutton, Eileen, Lee, Shoo K, Lee, Terry, Logan, Alexander G, Ganzevoort, Wessel, Welch, Ross, Thornton, Jim G, Moutquin, Jean-Marie

“…In this trial comparing less-tight control of hypertension (target diastolic blood pressure, 100 mm Hg) with tight control (85 mm Hg) among pregnant women,…”
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A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes by Durrer, Cody, McKelvey, Sean, Singer, Joel, Batterham, Alan M., Johnson, James D., Gudmundson, Kelsey, Wortman, Jay, Little, Jonathan P.

“…Type 2 diabetes can be treated, and sometimes reversed, with dietary interventions; however, strategies to implement these interventions while addressing…”
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Author Correction: Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial by Prior, Jerilynn C., Cameron, Andrea, Fung, Michelle, Hitchcock, Christine L., Janssen, Patricia, Lee, Terry, Singer, Joel

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Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada by Oliver, Matthew J, Thomas, Doneal, Balamchi, Shabnam, Ip, Jane, Naylor, Kyla, Dixon, Stephanie N, McArthur, Eric, Kwong, Jeff, Perl, Jeffrey, Atiquzzaman, Mohammad, Singer, Joel, Yeung, Angie, Hladunewich, Michelle, Yau, Kevin, Garg, Amit X, Leis, Jerome A, Levin, Adeera, Krajden, Mel, Blake, Peter G

“…Vaccination studies in the hemodialysis population have demonstrated decreased antibody response compared with healthy controls, but vaccine effectiveness for…”
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Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial by Prior, Jerilynn C., Cameron, Andrea, Fung, Michelle, Hitchcock, Christine L., Janssen, Patricia, Lee, Terry, Singer, Joel

“…This study tested progesterone for perimenopausal hot flush ± night sweat (vasomotor symptom, VMS) treatment. It was a double-blind, randomized trial of 300 mg…”
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Factors associated with frequent high-cost individuals with cystic fibrosis and their healthcare utilization and cost patterns by Desai, Sameer, Zhang, Wei, Sutherland, Jason M., Singer, Joel, Quon, Bradley S.

“…Cystic fibrosis (CF) is a progressive multi-organ disease with significant morbidity placing extensive demands on the healthcare system. Little is known about…”
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E-mental health in child psychiatry during COVID-19: an initial attitudinal study by Eapen, Valsamma, Dadich, Ann, Balachandran, Srilaxmi, Dani, Anitha, Howari, Rasha, Sequeria, Anupama Zeena, Singer, Joel D

“…Objective: COVID-19 propelled e-mental health within the Australian health system. It is important to learn from this to inform mental healthcare during future…”
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Pediatric post-discharge mortality in resource poor countries: a systematic review by Wiens, Matthew O, Pawluk, Shane, Kissoon, Niranjan, Kumbakumba, Elias, Ansermino, J Mark, Singer, Joel, Ndamira, Andrew, Larson, Charles

“…Mortality following hospital discharge is an important and under-recognized contributor to overall child mortality in developing countries. The primary…”
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A whole-joint, unidimensional, irreversible, and fine-grained MRI knee osteoarthritis severity score, based on cartilage, osteophytes and meniscus (OA-COM) by Sayre, Eric C, Guermazi, Ali, Nicolaou, Savvas, Esdaile, John M, Kopec, Jacek A, Singer, Joel, Wong, Hubert, Thorne, Anona, Cibere, Jolanda

“…Objective To develop a whole-joint, unidimensional, irreversible, and fine-grained MRI knee osteoarthritis (OA) severity score, based on cartilage, osteophytes…”
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Do younger women fare worse? Sex differences in acute myocardial infarction hospitalization and early mortality rates over ten years by Izadnegahdar, Mona, Singer, Joel, Lee, May K, Gao, Min, Thompson, Christopher R, Kopec, Jacek, Humphries, Karin H

“…Recent research has identified younger women as an "at-risk" population with rising prevalence of cardiac risk factors and excess mortality risk following…”
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Author Correction: A randomized controlled trial of pharmacist-led therapeutic carbohydrate and energy restriction in type 2 diabetes by Durrer, Cody, McKelvey, Sean, Singer, Joel, Batterham, Alan M., Johnson, James D., Gudmundson, Kelsey, Wortman, Jay, Little, Jonathan P.

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Clinical Correlates of Human Immunodeficiency Virus–1 (HIV-1) DNA and Inducible HIV-1 RNA Reservoirs in Peripheral Blood in Children With Perinatally Acquired HIV-1 Infection With Sustained Virologic Suppression for at Least 5 Years by Bitnun, Ari, Ransy, Doris G, Brophy, Jason, Kakkar, Fatima, Hawkes, Michael, Samson, Lindy, Annabi, Bayader, Pagliuzza, Amélie, Morand, Jacob-Adams, Sauve, Laura, Chomont, Nicolas, Lavoie, Stephanie, Kim, John, Sandstrom, Paul, Wender, Paul A, Lee, Terry, Singer, Joel, Read, Stanley E, Soudeyns, Hugo

“…Abstract Background The Early Pediatric Initiation Canada Child Cure Cohort (EPIC4) study is a prospective, multicenter, Canadian cohort study investigating…”
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The effects of vasopressin on acute kidney injury in septic shock by Gordon, Anthony C., Russell, James A., Walley, Keith R., Singer, Joel, Ayers, Dieter, Storms, Michelle M., Holmes, Cheryl L., Hébert, Paul C., Cooper, D. James, Mehta, Sangeeta, Granton, John T., Cook, Deborah J., Presneill, Jeffrey J.

“…Objective To compare the effects of vasopressin versus norepinephrine infusion on the outcome of kidney injury in septic shock. Design and setting Post-hoc…”
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Associations between MRI features versus knee pain severity and progression: Data from the Vancouver Longitudinal Study of Early Knee Osteoarthritis by Sayre, Eric C, Guermazi, Ali, Esdaile, John M, Kopec, Jacek A, Singer, Joel, Thorne, Anona, Nicolaou, Savvas, Cibere, Jolanda

“…To determine associations between features of osteoarthritis (OA) on MRI and knee pain severity and knee pain progression. Baseline, 3.3- and 7.5-year…”
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Economic burden of cystic fibrosis care in British Columbia by Desai, Sameer, Zhang, Wei, Sutherland, Jason M., PhD, Joel Singer, Zhou, Xingzuo, Quon, Bradley S.

“…RATIONALE: Cystic fibrosis (CF) is a progressive multi-organ disease with significant morbidity placing extensive demands on the health care system. No recent…”
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Blood Pressure and Heart Rate Variability and the Impact on Pregnancy Outcomes: A Systematic Review by Wilson, Milly G, Bone, Jeffrey N, Mistry, Hiten D, Slade, Laura J, Singer, Joel, von Dadelszen, Peter, Magee, Laura A

“…Long-term (visit-to-visit) blood pressure variability (BPV) and heart rate variability (HRV) outside pregnancy are associated with adverse cardiovascular…”
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A novel carbon-fibre adjustable reusable accessory (CARA) for supine breast positioning to reduce toxicity in breast adjuvant radiotherapy: a study protocol for a multicentre phase III randomized controlled trial by Duzenli, Cheryl, Chan, Elisa K, Bergman, Alanah M, Grahame, Sheri, Singer, Joel, Burns, Levi, Olson, Robert A

“…Abstract Background A novel device for supine positioning in breast radiotherapy for patients with large or pendulous breasts has been developed and tested in…”
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Effect of vitamin D on endothelial progenitor cells function by Hammer, Yoav, Soudry, Alissa, Levi, Amos, Talmor-Barkan, Yeela, Leshem-Lev, Dorit, Singer, Joel, Kornowski, Ran, Lev, Eli I

“…Endothelial progenitor cells (EPCs) are a population of bone marrow-derived cells, which have an important role in the process of endothelialization and…”
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