Search Results - "SINDEN, R. E"

The cell biology of malaria infection of mosquito: advances and opportunities by Sinden, R. E.

“…Summary Recent reviews (Feachem et al.; Alonso et al.) have concluded that in order to have a sustainable impact on the global burden of malaria, it is…”
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A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs by Ruecker, A, Mathias, D K, Straschil, U, Churcher, T S, Dinglasan, R R, Leroy, D, Sinden, R E, Delves, M J

“…Malaria elimination will require interventions that prevent parasite transmission from the human host to the mosquito. Experimentally, this is usually…”
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Transmission-blocking interventions eliminate malaria from laboratory populations by Blagborough, A. M., Churcher, T. S., Upton, L. M., Ghani, A. C., Gething, P. W., Sinden, R. E.

“…Transmission-blocking interventions aim to reduce the prevalence of infection in endemic communities by targeting Plasmodium within the insect host. Although…”
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Malaria, sexual development and transmission: retrospect and prospect by Sinden, R E

“…It is difficult to recapture the excitement of recent research into the malaria parasites. Plasmodium has shown itself to be a most elegant, resourceful and…”
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Comparative Assessment of Transmission-Blocking Vaccine Candidates against Plasmodium falciparum by Kapulu, M. C., Da, D. F., Miura, K., Li, Y, Blagborough, A. M., Churcher, T. S., Nikolaeva, D., Williams, A. R., Goodman, A. L., Sangare, I., Turner, A. V., Cottingham, M. G., Nicosia, A., Straschil, U., Tsuboi, T., Gilbert, S. C., Long, Carole A., Sinden, R. E., Draper, S. J., Hill, A. V. S., Cohuet, A., Biswas, S.

“…Malaria transmission-blocking vaccines (TBVs) target the development of Plasmodium parasites within the mosquito, with the aim of preventing malaria…”
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The flagellum in malarial parasites by Sinden, RE, Talman, A, Marques, SR, Wass, MN, Sternberg, MJE

“…The malarial parasites assemble flagella exclusively during the formation of the male gamete in the midgut of the female mosquito vector. The observation of…”
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DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccine Encoding Thrombospondin-Related Adhesion Protein but Not Circumsporozoite Protein Partially Protects Healthy Malaria-Naive Adults against Plasmodium falciparum Sporozoite Challenge by Dunachie, S.J, Walther, M, Epstein, J.E, Keating, S, Berthoud, T, Andrews, L, Andersen, R.F, Bejon, P, Goonetilleke, N, Poulton, I, Webster, D.P, Butcher, G, Watkins, K, Sinden, R.E, Levine, G.L, Richie, T.L, Schneider, J, Kaslow, D, Gilbert, S.C, Carucci, D.J, Hill, A.V.S

“…The safety, immunogenicity, and efficacy of DNA and modified vaccinia virus Ankara (MVA) prime-boost regimes were assessed by using either…”
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Identification of xanthurenic acid as the putative inducer of malaria development in the mosquito by Sinden, R. E, Morris, H. R, Billker, O, Lindo, V, Panico, M, Etienne, A. E, Paxton, T, Dell, A, Rogers, M

“…Malaria is transmitted from vertebrate host to mosquito vector by mature sexual blood-living stages called gametocytes,. Within seconds of ingestion into the…”
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Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations by Upton, L M, Brock, P M, Churcher, T S, Ghani, A C, Gething, P W, Delves, M J, Sala, K A, Leroy, D, Sinden, R E, Blagborough, A M

“…To achieve malarial elimination, we must employ interventions that reduce the exposure of human populations to infectious mosquitoes. To this end, numerous…”
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Proteomic analysis of Plasmodium in the mosquito: progress and pitfalls by Wass, M N, Stanway, R, Blagborough, A M, Lal, K, Prieto, J H, Raine, D, Sternberg, M J E, Talman, A M, Tomley, F, Yates, 3rd, J, Sinden, R E

“…Here we discuss proteomic analyses of whole cell preparations of the mosquito stages of malaria parasite development (i.e. gametocytes, microgamete, ookinete,…”
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Molecular interactions between Plasmodium and its insect vectors by Sinden, R. E.

“…Summary Our understanding of the intricate interactions between the malarial parasite and the mosquito vector is complicated both by the number and diversity…”
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Transmission blocking potency and immunogenicity of a plant-produced Pvs25-based subunit vaccine against Plasmodium vivax by Blagborough, A.M, Musiychuk, K, Bi, H, Jones, R.M, Chichester, J.A, Streatfield, S, Sala, K.A, Zakutansky, S.E, Upton, L.M, Sinden, R.E, Brian, I, Biswas, S, Sattabonkot, J, Yusibov, V

“…Abstract Malaria transmission blocking (TB) vaccines (TBVs) directed against proteins expressed on the sexual stages of Plasmodium parasites are a potentially…”
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The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti by Alavi, Y., Arai, M., Mendoza, J., Tufet-Bayona, M., Sinha, R., Fowler, K., Billker, O., Franke-Fayard, B., Janse, C.J., Waters, A., Sinden, R.E.

“…Knowledge of parasite–mosquito interactions is essential to develop strategies that will reduce malaria transmission through the mosquito vector. In this study…”
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Targeting the Parasite to Suppress Malaria Transmission by Sinden, R E

“…This article attempts to draw together current knowledge on the biology of Plasmodium and experience gained from past control campaigns to interpret and guide…”
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A proteomic analysis of malaria biology: integration of old literature and new technologies by Sinden, R.E.

“…The genomic revolution has brought a new vitality into research on Plasmodium, its insect and vertebrate hosts. At the cellular level nowhere is the impact…”
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Mosquito–malaria interactions: a reappraisal of the concepts of susceptibility and refractoriness by Sinden, R.E, Alavi, Yasmene, Raine, J.D

“…This paper considers the available literature on the transmission of malaria by insects and concludes that, in contrast to the commonly held view (that implies…”
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The roles of temperature, pH and mosquito factors as triggers of male and female gametogenesis of Plasmodium berghei in vitro by Billker, O, Shaw, M K, Margos, G, Sinden, R E

“…Developmentally arrested malarial gametocytes undergo gamete formation in the mosquito midgut immediately after ingestion of the infected bloodmeal. In the…”
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Determination of mosquito bloodmeal pH in situ by ion-selective microelectrode measurement: implications for the regulation of malarial gametogenesis by Billker, O, Miller, A J, Sinden, R E

“…Malarial gametocytes circulate in the peripheral blood of the vertebrate host as developmentally arrested intra-erythrocytic cells, which only resume…”
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Knockout of the Rodent Malaria Parasite Chitinase PbCHT1 Reduces Infectivity to Mosquitoes by DESSENS, Johannes T, MENDOZA, Jacqui, CLAUDIANOS, Charles, VINETZ, Joseph M, KHATER, Emad, HASSARD, Stuart, RANAWAKA, Gaya R, SINDEN, Robert E

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Regulation of infectivity of Plasmodium to the mosquito vector by Sinden, R E, Butcher, G A, Billker, O, Fleck, S L

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