Search Results - "SIMUNIC, Juraj"
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DADP: the database of anuran defense peptides
Published in Bioinformatics (Oxford, England) (15-05-2012)“…Anuran tissues, and especially skin, are a rich source of bioactive peptides and their precursors. We here present a manually curated database of antimicrobial…”
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2
The mitotic spindle is chiral due to torques within microtubule bundles
Published in Nature communications (03-09-2018)“…Mitosis relies on forces generated in the spindle, a micro-machine composed of microtubules and associated proteins. Forces are required for the congression of…”
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3
Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers
Published in eLife (21-10-2022)“…The human mitotic spindle is made of microtubules nucleated at centrosomes, at kinetochores, and from pre-existing microtubules by the augmin complex. However,…”
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Predicting the Minimal Inhibitory Concentration for Antimicrobial Peptides with Rana-Box Domain
Published in Journal of chemical information and modeling (26-10-2015)“…The global spreading of multidrug resistance has motivated the search for new antibiotic classes including different types of antimicrobial peptides (AMPs)…”
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PGLa-H tandem-repeat peptides active against multidrug resistant clinical bacterial isolates
Published in Biochimica et biophysica acta. Biomembranes (01-02-2017)“…Antimicrobial peptides (AMPs) are promising candidates for new antibiotic classes but often display an unacceptably high toxicity towards human cells. A…”
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Improving the Selectivity of Antimicrobial Peptides from Anuran Skin
Published in Journal of chemical information and modeling (21-12-2012)“…Anuran skin is known to be a rich source of antimicrobial peptides although their therapeutic potential is often limited due to their toxicity against…”
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7
Meeting report - Mitotic spindle: from living and synthetic systems to theory
Published in Journal of cell science (02-09-2019)“…Leading scientists from the field of mitotic spindle research gathered from 24-27 March 2019 to participate in the first 'Mitotic spindle: From living and…”
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Journal Article Conference Proceeding -
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Design of α-helical antimicrobial peptides with a high selectivity index
Published in Expert opinion on drug discovery (03-10-2019)“…: Low-molecular-weight antibiotics are gradually rendered ineffective by multidrug-resistant bacteria. Promising replacements are fast-acting antimicrobial…”
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Mitotic Spindle Assembly: Building the Bridge between Sister K-Fibers
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01-10-2016)“…The mitotic spindle performs the task of physically dividing the genetic material between the newly formed daughter cells. To achieve this, bundles of…”
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Meiotic Spindle Has a Soft Spot
Published in Developmental cell (22-04-2019)“…The spindle relies on forces exerted by microtubules and motor proteins to align and segregate chromosomes. In this issue of Developmental Cell, Takagi et al…”
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Maximum Entropy Production Theorem for Transitions between Enzyme Functional States and Its Applications
Published in Entropy (Basel, Switzerland) (29-07-2019)“…Transitions between enzyme functional states are often connected to conformational changes involving electron or proton transport and directional movements of…”
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Evidence for distinct functions of MRE11 in Arabidopsis meiosis
Published in PloS one (21-10-2013)“…The evolutionary conserved Mre11/Rad50/Nbs1 complex functions as one of the guardians of genome integrity in eukaryotes; it is required for the double-strand…”
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The maximum entropy production requirement for proton transfers enhances catalytic efficiency for β-lactamases
Published in Biophysical chemistry (01-01-2019)“…Movement of charges during enzyme catalytic cycle may be due to conformational changes, or to fast electron or proton transfer, or to both events. In each…”
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Trichoplaxin — A new membrane-active antimicrobial peptide from placozoan cDNA
Published in Biochimica et biophysica acta (01-05-2014)“…A method based on the use of signal peptide sequences from antimicrobial peptide (AMP) precursors was used to mine a placozoa expressed sequence tag database…”
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Torques and Forces in the Mitotic Spindle
Published in Biophysical journal (02-02-2018)Get full text
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The impact of new standards and new technological solutions on process information modelling
Published in 2012 16th IEEE Mediterranean Electrotechnical Conference (01-03-2012)“…This paper represents the basic concepts for a process information model that will satisfy all the needs of a modern power system under the circumstances of…”
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Conference Proceeding -
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Characterization of a membrane-bound angiotensin-converting enzyme isoform in crayfish testis and evidence for its release into the seminal fluid
Published in The FEBS journal (01-09-2009)“…In the present study, an isoform of angiotensin-converting enzyme was characterized from the testis of a decapod crustacean, the crayfish Astacus…”
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Evidence for Distinct Functions of MRE11 in Arabidopsis Meiosis: e78760
Published in PloS one (01-10-2013)“…The evolutionary conserved Mre11/Rad50/Nbs1 complex functions as one of the guardians of genome integrity in eukaryotes; it is required for the double-strand…”
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Journal Article -
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Evidence for an angiotensin-converting enzyme (ACE) polymorphism in the crayfish Astacus leptodactylus
Published in Peptides (New York, N.Y. : 1980) (01-07-2007)“…The present study was initiated to characterize angiotensin-converting enzyme (ACE) in Crustaceans. Using degenerate DNA primers deduced from consensus…”
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Journal Article