Search Results - "SIMPSON, R. U"

Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression by Pan, Q, Simpson, RU

“…The expression of c-myc is decreased by 1,25-(OH)2D(3) during HL-60 cell differentiation. Concomitantly, 1,25-(OH)2D(3) increases the expression and DNA…”
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1,25-Dihydroxyvitamin D3 regulation of cardiac myocyte proliferation and hypertrophy by O'Connell, T D, Berry, J E, Jarvis, A K, Somerman, M J, Simpson, R U

“…We previously demonstrated that 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] inhibits myocyte maturation (T. D. O'Connell, D. A. Giacherio, A. K. Jarvis, and R. U…”
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Inhibition of cancer cell growth by calcium channel antagonists in the athymic mouse by TAYLOR, J. M, SIMPSON, R. U

“…The calcium channel antagonists (CCAs) amlodipine, diltiazem, and verapamil inhibited HT-39 human breast cancer cell proliferation in a concentration-dependent…”
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Vitamin D deficiency in the spontaneously hypertensive heart failure [SHHF] prone rat by Przybylski, R, Mccune, S, Hollis, B, Simpson, R.U

“…Abstract Background and aims Vitamin D deficiency has been associated with the etiology and pathogenesis of heart disease including congestive heart failure…”
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Vitamin D3 and cardiovascular function in rats by WEISHAAR, R. E, SIMPSON, R. U

“…We have previously identified a receptor for 1,25-dihydroxyvitamin D3 in myocardial cells (Simpson, R.U. 1983. Circulation. 68:239.). To establish the…”
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Identification of 1,25-dihydroxyvitamin D3 receptors and activities in muscle by Simpson, R U, Thomas, G A, Arnold, A J

“…Cytosols from cultured myoblast cells (G-8 and H9c2) prepared in high salt (0.3 M KCl) possesses receptor like proteins for 1,25-dihydroxyvitamin D3…”
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Involvement of vitamin D3 with cardiovascular function. III. Effects on physical and morphological properties by Weishaar, R.E, Kim, S.N, Saunders, D.E, Simpson, R.U

“…We have previously shown that depletion of vitamin D3 in rats results in a large increase in the contractile function of isolated hearts (R. E. Weishaar, J…”
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Involvement of vitamin D3 with cardiovascular function. II. Direct and indirect effects by Weishaar, R E, Simpson, R U

“…To determine whether the changes in cardiovascular function that accompany vitamin D3 deficiency are the direct result of hypovitaminosis D3 or a response to…”
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1,25-Dihydroxyvitamin D3 regulation of c-myc protooncogene transcription. Possible involvement of protein kinase C by SIMPSON, R. U, HSU, T, WENDT, M. D, TAYLOR, J. M

“…1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3) regulates the expression of c-myc protooncogene in HL-60 promyelocytic leukemia cells (Reitzma, P. H., Rothberg, P. G.,…”
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Transcriptional regulation of the c-myc protooncogene by 1,25-dihydroxyvitamin D3 in HL-60 promyelocytic leukemia cells by Simpson, R.U., Hsu, T., Begley, D.A., Mitchell, B.S., Alizadeh, B.N.

“…Exposure of HL-60 promyelocytic leukemia cells to calcitriol results in a decrease in steady-state levels of c-myc mRNA and induces cellular differentiation…”
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1,25-Dihydroxyvitamin D3 regulation of phorbol ester receptors in HL-60 leukemia cells by Martell, R.E., Simpson, R.U., Taylor, J.M.

“…In this study the relationship between cell binding of phorbol 12,13-dibutyrate (PDBu) and induction of differentiation by 1,25-dihydroxyvitamin D3…”
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Induction of Differentiation of Human Promyelocytic Leukemia Cell Line HL-60 by Retinoyl Glucuronide, a Biologically Active Metabolite of Vitamin A by Zile, Maija H., Cullum, Malford E., Simpson, Robert U., Barua, Arun B., Swartz, Deborah A.

“…We examined the differentiation activity of retinoyl β -D-glucuronide, a biologically active physiological metabolite of vitamin A, using the human…”
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Identification of lamin B and histones as 1,25-dihydroxyvitamin D3-regulated nuclear phosphoproteins in HL-60 cells by MARTELL, R. E, STRAHLER, J. R, SIMPSON, R. U

“…1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3)-induced differentiation of HL-60 leukemia cells is accompanied by a number of cellular changes including regulation of…”
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The involvement of the endocrine system in regulating cardiovascular function: emphasis on vitamin D3 by Weishaar, R E, Simpson, R U

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Characterization of a Receptor-Like Protein for 1,25-Dihydroxyvitamin D3 in Rat Skin by Simpson, Robert U., DeLuca, Hector F.

“…Isolated rat epidermis possesses a cytosolic 3.5 S receptor-like protein for 1,25-dihydroxyvitamin D3. This 3.5S binder has a high affinity (Kd=1.4× 10-10M)…”
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Production and degradation of calcitriol in renal failure rats by Hsu, C H, Patel, S, Young, E W, Simpson, R U

“…We studied the metabolism of calcitriol in renal failure achieved by nephrectomy in three groups of rats. Group 1 (n = 7) had sham operation of nephrectomy…”
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Purification of chicken intestinal receptor for 1 alpha, 25-dihydroxyvitamin D3 to apparent homogeneity by Simpson, R U, DeLuca, H F

“…The chicken intestinal 1 alpha, 25-dihydroxyvitamin D3 receptor-like protein has been purified to apparent homogeneity as determined by sodium dodecyl sulfate…”
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Calcitriol synthesis is decreased in spontaneously hypertensive rats by Patel, Sanjeev, Simpson, Robert U., Hsu, Chen H.

“…Calcitriol synthesis is decreased in spontaneously hypertensive rats. To investigate the mechanisms of abnormal calcium metabolism, such as hypocalcemia,…”
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Production and metabolic clearance of calcitriol in acute renal failure by Hsu, Chen H., Patel, Sanjeev, Young, Eric W., Simpson, Robert U.

“…Production and metabolic clearance of calcitriol in acute renal failure. Metabolic clearance rate (MCR) and production rate (PR) of calcitriol were studied…”
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Involvement of 1,25-dihydroxyvitamin D3 in regulating myocardial calcium metabolism: physiological and pathological actions by Simpson, R U, Weishaar, R E

“…The role of the prohormone vitamin D3 in regulating calcium and phosphate metabolism in the intestine, kidney, and bone has been known for several decades…”
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