Search Results - "SIMONIAN, Nancy"
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Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis
Published in The New England journal of medicine (28-09-2000)“…Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system that most commonly affects women, with an onset typically…”
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First Rounders: Nancy Simonian
Published in Nature biotechnology (01-08-2021)Get full text
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Functional alterations in Alzheimer's disease: selective loss of mitochondrial-encoded cytochrome oxidase mRNA in the hippocampal formation
Published in Journal of neuropathology and experimental neurology (01-09-1994)“…The activity of cytochrome oxidase (CO), the terminal enzyme of the electron transport chain, has been reported to be decreased in the brains of individuals…”
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Functional alterations in Alzheimer's disease: decreased glucose transporter 3 immunoreactivity in the perforant pathway terminal zone
Published in Journal of neuropathology and experimental neurology (01-01-1995)“…Positron emission tomography (PET) studies measuring glucose utilization have demonstrated cerebral hypometabolism in Alzheimer's disease (AD). The anatomic…”
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Functional alterations in Alzheimer's disease: diminution of cytochrome oxidase in the hippocampal formation
Published in Journal of neuropathology and experimental neurology (01-11-1993)“…In Alzheimer's disease, the relationship between structural alterations such as neurofibrillary tangles and senile plaques and neuronal function is unknown…”
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Supporting US public health experts
Published in Nature biotechnology (01-12-2020)Get full text
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Author Correction: Supporting US public health experts
Published in Nature biotechnology (2021)“…A Correction to this paper has been published: https://doi.org/10.1038/s41587-020-00792-5…”
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Chinese scientists and US leadership in the life sciences
Published in Nature biotechnology (01-11-2019)Get full text
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Biotech leaders call for free press
Published in Nature biotechnology (01-10-2018)Get full text
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US immigration order strikes against biotech
Published in Nature biotechnology (01-03-2017)Get full text
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Use of the multiple sclerosis functional composite as an outcome measure in a phase 3 clinical trial
Published in Archives of neurology (Chicago) (01-06-2001)“…The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional clinical outcome measure that includes quantitative tests of leg function/ambulation…”
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Factors that predict health-related Quality of Life in patients with relapsing-remitting multiple sclerosis
Published in Multiple sclerosis (01-02-2003)“…Health-Related Quality of Life (HRQoL) research is gaining acceptance in the field of multiple sclerosis (MS). Little is known about what precipitates quality…”
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Glycoprotein IIb/IIIa inhibitor therapy and outcomes after percutaneous coronary intervention
Published in The American journal of cardiology (15-09-2003)Get full text
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Cerebrospinal fluid abnormalities in a phase III trial of Avonex® (IFNβ-1a) for relapsing multiple sclerosis
Published in Journal of neuroimmunology (1999)“…Background and objective: This report provides results of CSF analyses done in a subset of relapsing remitting MS patients participating in a…”
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Self-reported visual dysfunction in multiple sclerosis: results from the 25-Item National Eye Institute Visual Function Questionnaire (VFQ-25)
Published in Multiple sclerosis (01-12-2000)“…Visual impairment is one of the most common clinical manifestations of Multiple Sclerosis (MS), and is strongly related to overall health-related quality of…”
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Factors that predict Health-Related Q uality of Life in patients with relapsing -remitting multiple sclerosis
Published in Multiple sclerosis (01-02-2003)“…Health-Related Q uality of Life (HRQ oL) research is gaining acceptance in the field of multiple sclerosis (MS). Little is known about what precipitates…”
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Lupus anticoagulants, anticardiolipin antibodies, and cerebral ischemia
Published in Stroke (1970) (01-02-1989)“…We studied 23 patients suffering cerebral ischemia who also had laboratory evidence of either a lupus anticoagulant (LA) or an abnormal anticardiolipin…”
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Factors That Predict HRQOL in Patients with Re-lapsing Remitting MS: Results of an 8-Year Study
Published in Quality of life research (01-05-2001)Get full text
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Leptomeningeal myelomatosis presenting with mental status changes and other neurologic findings
Published in Cancer (01-10-1992)“…Leptomeningeal myelomatosis is a rare complication of multiple myeloma. The authors identified and studied three patients with leptomeningeal myelomatosis and…”
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