Search Results - "SIMON, M. S"

The role of diet in the aetiopathogenesis of inflammatory bowel disease by Khalili, Hamed, Chan, Simon S. M., Lochhead, Paul, Ananthakrishnan, Ashwin N., Hart, Andrew R., Chan, Andrew T.

“…Crohn’s disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. Although the…”
Get full text

CEO Gender, Ethical Leadership, and Accounting Conservatism by Ho, Simon S. M., Li, Annie Yuansha, Tam, Kinsun, Zhang, Feida

“…Since male CEOs dominate corporate leadership, the literature on top management decision making suffers from an implicit masculine bias. Although research…”
Get full text

Altered Patterns of Fungal Keratitis at a London Ophthalmic Referral Hospital: An Eight-Year Retrospective Observational Study by Ong, Hon Shing, Fung, Simon S.M, Macleod, David, Dart, John K.G, Tuft, Stephen J, Burton, Matthew J

“…Abstract Purpose In previous studies of fungal keratitis (FK) from temperate countries, yeasts were the predominant isolates with ocular surface disease (OSD)…”
Get full text

Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps by Wu, Chung Wah, Ng, Simon S M, Dong, Yu Juan, Ng, Siew Chien, Leung, Wing Wa, Lee, Chung Wa, Wong, Yee Ni, Chan, Francis K L, Yu, Jun, Sung, Joseph J Y

“…The detection of molecular markers in stool samples is a potential strategy for colorectal cancer (CRC) screening. This study evaluated the feasibility of…”
Get more information

Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments by Sun, Kun, Jiang, Peiyong, Chan, K. C. Allen, Wong, John, Cheng, Yvonne K. Y., Liang, Raymond H. S., Chan, Wai-kong, Ma, Edmond S. K., Chan, Stephen L., Cheng, Suk Hang, Chan, Rebecca W. Y., Tong, Yu K., Ng, Simon S. M., Wong, Raymond S. M., Hui, David S. C., Leung, Tse Ngong, Leung, Tak Y., Lai, Paul B. S., Chiu, Rossa W. K., Lo, Yuk Ming Dennis

“…Plasma consists of DNA released from multiple tissues within the body. Using genome-wide bisulfite sequencing of plasma DNA and deconvolution of the sequencing…”
Get full text

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer by Tsang, Wing Pui, Ng, Enders K.O., Ng, Simon S.M., Jin, Hongchuan, Yu, Jun, Sung, Joseph J.Y., Kwok, Tim Tak

“…H19 is an imprinted oncofetal non-coding RNA recently shown to be the precursor of miR-675. The pathophysiological roles of H19 and its mature product miR-675…”
Get full text

Activation of PTEN by inhibition of TRPV4 suppresses colon cancer development by Liu, Xiaoyu, Zhang, Peng, Xie, Chuanming, Sham, Kathy W. Y., Ng, Simon S. M., Chen, Yangchao, Cheng, Christopher H. K.

“…Transient receptor potential vanilloid type 4 (TRPV4) is a Ca 2+ -permeable cation channel that is known to be an osmosensor and thermosensor. Currently,…”
Get full text

Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing by Chan, K. C. Allen, Jiang, Peiyong, Chan, Carol W. M., Sun, Kun, Wong, John, Hui, Edwin P., Chan, Stephen L., Chan, Wing Cheong, Hui, David S. C., Ng, Simon S. M., Chan, Henry L. Y., Wong, Cesar S. C., Ma, Brigette B. Y., Chan, Anthony T. C., Lai, Paul B. S., Sun, Hao, Chiu, Rossa W. K., Lo, Y. M. Dennis

“…We explored the detection of genome-wide hypomethylation in plasma using shotgun massively parallel bisulfite sequencing as a marker for cancer…”
Get full text

Environmental Factors in the Relapse and Recurrence of Inflammatory Bowel Disease: A Review of the Literature by Martin, Thomas D., Chan, Simon S. M., Hart, Andrew R.

“…Introduction The causes of relapse in patients with Crohn’s disease (CD) and ulcerative colitis (UC) are largely unknown. This paper reviews the…”
Get full text

MicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancer by Wu, Chung-Wah, Dong, Yu-Juan, Liang, Qiao-Yi, He, Xin-Qi, Ng, Simon S M, Chan, Francis K L, Sung, Joseph J Y, Yu, Jun

“…miR-18a is one of the most up-regulated miRNAs in colorectal cancers (CRC) based on miRNA profiling. In this study, we examined the functional significance of…”
Get full text

Capsule Endoscopy or Angiography in Patients With Acute Overt Obscure Gastrointestinal Bleeding: A Prospective Randomized Study With Long-Term Follow-Up by LEUNG, Wai K, HO, Simon S. M, LAU, James Y. W, SUEN, Bing-Yee, LAI, Larry H, YU, Simon, ENDERS, K. W, NG, Simon S. M, CHIU, Philip W. Y, SUNG, Joseph J. Y, CHAN, Francis K. L

“…Both capsule endoscopy (CE) and angiography have been recommended as first investigation for patients with acute overt obscure gastrointestinal bleeding…”
Get full text

Comparative analysis of European residency programs: benchmarking and harmonizing ophthalmology training in Europe by Anaya-Alaminos, Roberto, Rassmussen, Marie Louise, Fung, Simon S. M., Potic, Jelena, González-Andrades, Miguel

“…Background/objectives This study aims to benchmark the training programs of European ophthalmology residents. Subjects/Methods An online survey, aimed at…”
Get full text

Novel recurrently mutated genes and a prognostic mutation signature in colorectal cancer by Yu, Jun, Wu, William K K, Li, Xiangchun, He, Jun, Li, Xiao-Xing, Ng, Simon S M, Yu, Chang, Gao, Zhibo, Yang, Jie, Li, Miao, Wang, Qiaoxiu, Liang, Qiaoyi, Pan, Yi, Tong, Joanna H, To, Ka F, Wong, Nathalie, Zhang, Ning, Chen, Jie, Lu, Youyong, Lai, Paul B S, Chan, Francis K L, Li, Yingrui, Kung, Hsiang-Fu, Yang, Huanming, Wang, Jun, Sung, Joseph J Y

“…Characterisation of colorectal cancer (CRC) genomes by next-generation sequencing has led to the discovery of novel recurrently mutated genes. Nevertheless,…”
Get more information

MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene by He, Xinqi, Dong, Yujuan, Wu, Chung Wah, Zhao, Zengren, Ng, Simon S M, Chan, Francis K L, Sung, Joseph J Y, Yu, Jun

“…Deregulated miRNAs participate in colorectal carcinogenesis. In this study, miR-218 was found to be downregulated in human colorectal cancer (CRC) by miRNA…”
Get full text

FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells by Ren, Shun X, Shen, Jin, Cheng, Alfred S L, Lu, Lan, Chan, Ruby L Y, Li, Zhi J, Wang, Xiao J, Wong, Clover C M, Zhang, Lin, Ng, Simon S M, Chan, Franky L, Chan, Francis K L, Yu, Jun, Sung, Joseph J Y, Wu, William K K, Cho, Chi H

“…Host immune peptides, including cathelicidins, have been reported to possess anticancer properties. We previously reported that LL-37, the only cathelicidin in…”
Get full text

Corporate Governance and Earnings Management by Classification Shifting by Haw, In-Mu, Ho, Simon S.M., Li, Annie Yuansha

“…This study examines earnings management through classification shifting and the monitoring role played by corporate governance mechanisms in curbing such…”
Get full text

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin by Sun, Kun, Jiang, Peiyong, Cheng, Suk Hang, Cheng, Timothy H T, Wong, John, Wong, Vincent W S, Ng, Simon S M, Ma, Brigette B Y, Leung, Tak Y, Chan, Stephen L, Mok, Tony S K, Lai, Paul B S, Chan, Henry L Y, Sun, Hao, Chan, K C Allen, Chiu, Rossa W K, Lo, Y M Dennis

“…Cell-free DNA (cfDNA) in human plasma is a class of biomarkers with many current and potential future diagnostic applications. Recent studies have shown that…”
Get full text

Harmonizing ophthalmic residency surgical training across Europe: A proposed surgical curriculum by González-Andrades, Miguel, Fung, Simon S. M., Potic, Jelena, Chidambaram, Jaya D., Karimi, Ayesha, Quigley, Clare, Pontoppidan-Toms, Radka, Scott, Andrew, Rasmussen, Marie Louise R.

“…Background One of the core aims of the European Union of Medical Specialists is to harmonize training across Europe by creating European Training Requirements…”
Get full text

Concentrated control, institutions, and banking sector: An international study by Haw, In-Mu, Ho, Simon S.M., Hu, Bingbing, Wu, Donghui

“…Using a broad sample of listed commercial banks in East Asia and Western Europe, this paper investigates the relations among concentrated control, a set of…”
Get full text

Vector Projectile Imaging: Time-Resolved Dynamic Visualization of Complex Flow Patterns by Yiu, Billy Y.S, Lai, Simon S.M, Yu, Alfred C.H

“…Abstract Achieving non-invasive, accurate and time-resolved imaging of vascular flow with spatiotemporal fluctuations is well acknowledged to be an ongoing…”
Get full text