Search Results - "SIMOES, Lutiana R"
-
1
Pathophysiology of neonatal acute bacterial meningitis
Published in Journal of medical microbiology (01-12-2013)“…Neonatal meningitis is a severe acute infectious disease of the central nervous system and an important cause of morbidity and mortality worldwide. The…”
Get full text
Journal Article -
2
Brain–blood barrier breakdown and pro-inflammatory mediators in neonate rats submitted meningitis by Streptococcus pneumoniae
Published in Brain research (30-08-2012)“…Abstract Neonatal meningitis is an illness characterized by inflammation of the meninges and occurring within the birth and the first 28 days of life. Invasive…”
Get full text
Journal Article -
3
Klebsiella pneumoniae meningitis induces memory impairment and increases pro-inflammatory host response in the central nervous system of Wistar rats
Published in Journal of medical microbiology (01-01-2014)“…Klebsiella pneumoniae meningitis has recently become an increasingly common cause of central nervous system infection. The invasion of bacteria within the…”
Get full text
Journal Article -
4
A systematic review of evidence for the role of inflammatory biomarkers in bipolar patients
Published in Journal of psychiatric research (01-09-2017)“…Bipolar disorder (BD) is a neuropsychiatric disorder that is characterized by a phasic course of affective episodes interspersed with a euthymic state…”
Get full text
Journal Article -
5
Role of Microglial Activation in the Pathophysiology of Bacterial Meningitis
Published in Molecular neurobiology (01-04-2016)“…Bacterial meningitis is a life-threatening infection associated with cognitive impairment in many survivors. The pathogen invades the central nervous system…”
Get full text
Journal Article -
6
Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis
Published in Molecular neurobiology (01-08-2015)“…Pneumococcal meningitis is a serious infection of the central nervous system (CNS) with high fatality rates that causes reduced psychomotor performance, slight…”
Get full text
Journal Article -
7
Postmortem Evidence of Brain Inflammatory Markers and Injury in Septic Patients: A Systematic Review
Published in Critical care medicine (01-03-2022)“…Sepsis is a life-threatening organ dysfunction caused by a host's unregulated immune response to eliminate the infection. After hospitalization, sepsis…”
Get full text
Journal Article -
8
The translocator protein (18kDa) and its role in neuropsychiatric disorders
Published in Neuroscience and biobehavioral reviews (01-12-2017)“…•Inflammation is associated with a marked up-regulation of TSPO.•TSPO serves as an imaging biomarker of brain neuroinflammatory disorders.•TSPO is up-regulated…”
Get full text
Journal Article -
9
Microglial Activation and Psychotic Disorders: Evidence from Pre-clinical and Clinical Studies
Published in Current topics in behavioral neurosciences (01-01-2020)“…Clinical and pre-clinical studies have demonstrated an important role of neuroinflammation in the etiology of schizophrenia. While the underlying mechanisms…”
Get more information
Journal Article -
10
Ketamine potentiates oxidative stress and influences behaviour and inflammation in response to lipolysaccharide (LPS) exposure in early life
Published in Neuroscience (14-06-2017)“…Highlights • Effects of LPS in neonatal rats with administration of ketamine in adulthood as schizophrenia model. • Neonatal LPS exposure increases oxidative…”
Get full text
Journal Article -
11
Cannabidiol reduces host immune response and prevents cognitive impairments in Wistar rats submitted to pneumococcal meningitis
Published in European journal of pharmacology (15-12-2012)“…Pneumococcal meningitis is a life-threatening disease characterized by an acute infection affecting the pia matter, arachnoid and subarachnoid space. The…”
Get full text
Journal Article -
12
Prevention of Memory Impairment and Neurotrophic Factors Increased by Lithium in Wistar Rats Submitted to Pneumococcal Meningitis Model
Published in Mediators of inflammation (01-01-2017)“…The aim of this study was to investigate the effects of lithium on brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and glial cell…”
Get full text
Journal Article -
13
Temporal changes of oxidative stress markers in Escherichia coli K1-induced experimental meningitis in a neonatal rat model
Published in Neuroscience letters (13-07-2017)“…•E.coli induced neonatal meningitis is the most common serious infection of the CNS.•Experimental meningitis by E.coli increases oxidative stress in rat…”
Get full text
Journal Article -
14
Imipramine treatment reverses depressive- and anxiety-like behaviors, normalize adrenocorticotropic hormone, and reduces interleukin-1β in the brain of rats subjected to experimental periapical lesion
Published in Pharmacological reports (01-02-2019)“…A periodontal lesion is a consequence of chronic inflammatory processes, itself triggered by a bacterial infection of the pulpal and endodontic…”
Get more information
Journal Article -
15
Targets for adjunctive therapy in pneumococcal meningitis
Published in Journal of neuroimmunology (15-01-2015)“…Abstract Pneumococcal meningitis is a severe infectious disease of the central nervous system (CNS) and a significant cause of morbidity and mortality…”
Get full text
Journal Article -
16
Depression-Like Adult Behaviors may be a Long-Term Result of Experimental Pneumococcal Meningitis in Wistar Rats Infants
Published in Neurochemical research (01-10-2016)“…Pneumococcal meningitis is a life-threatening infection of the central nervous system (CNS) with a high mortality rate. In addition to causing severe…”
Get full text
Journal Article -
17
Folic acid prevented cognitive impairment in experimental pneumococcal meningitis
Published in Journal of Neural Transmission (01-05-2015)“…Streptococcus pneumoniae is a common cause of bacterial meningitis, with a high mortality rate and neurological sequelae. In contrast, folic acid plays an…”
Get full text
Journal Article -
18
Inhibition of matrix metalloproteinases-2 and -9 prevents cognitive impairment induced by pneumococcal meningitis in Wistar rats
Published in Experimental biology and medicine (Maywood, N.J.) (01-02-2014)“…Pneumococcal meningitis is a relevant clinical disease characterized by an intense inflammatory reaction into the subarachnoid and ventricular spaces, leading…”
Get more information
Journal Article -
19
Role of Oxidative Stress in the Pathophysiology of Pneumococcal Meningitis
Published in Oxidative medicine and cellular longevity (01-01-2013)“…Pneumococcal meningitis is a life-threatening disease characterized by an acute purulent infection affecting the pia mater, the arachnoid, and the subarachnoid…”
Get full text
Journal Article -
20
Does Infection-Induced Immune Activation Contribute to Dementia?
Published in Aging and disease (01-10-2015)“…The central nervous system (CNS) is protected by a complex blood-brain barrier system; however, a broad diversity of virus, bacteria, fungi, and protozoa can…”
Get full text
Journal Article