Search Results - "SIMÕES, DAVINA"
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Menstrual cycle-associated modulations in neuromuscular function and fatigability of the knee extensors in eumenorrheic women
Published in Journal of applied physiology (1985) (01-06-2019)“…Sex hormone concentrations of eumenorrheic women typically fluctuate across the menstrual cycle and can affect neural function such that estrogen has…”
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2
An integrin axis induces IFN-β production in plasmacytoid dendritic cells
Published in The Journal of cell biology (05-09-2022)“…Type I interferon (IFN) production by plasmacytoid dendritic cells (pDCs) has been mainly studied in the context of Toll-like receptor (TLR) activation. In the…”
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3
TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic Disease
Published in The Journal of immunology (1950) (01-05-2016)“…T cell Ig and ITIM domain receptor (TIGIT), expressed on T, NK, and regulatory T cells, is known as an inhibitory molecule that limits autoimmunity, antiviral…”
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4
Osteopontin expression by CD103⁻ dendritic cells drives intestinal inflammation
Published in Proceedings of the National Academy of Sciences - PNAS (04-03-2014)“…Intestinal CD103 ⁻ dendritic cells (DCs) are pathogenic for colitis. Unveiling molecular mechanisms that render these cells proinflammatory is important for…”
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5
Glucocorticoid and estrogen receptors are reduced in mitochondria of lung epithelial cells in asthma
Published in PloS one (27-06-2012)“…Mitochondrial glucocorticoid (mtGR) and estrogen (mtER) receptors participate in the coordination of the cell's energy requirement and in the mitochondrial…”
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Effects of rehabilitative exercise on peripheral muscle TNFα, IL-6, IGF-I and MyoD expression in patients with COPD
Published in Thorax (01-11-2007)“…Background:Skeletal muscle wasting commonly occurs in patients with chronic obstructive pulmonary disease (COPD) and has been associated with the presence of…”
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7
Osteopontin drives KRAS-mutant lung adenocarcinoma
Published in Carcinogenesis (New York) (12-08-2020)“…Increased expression of osteopontin (secreted phosphoprotein 1, SPP1) is associated with aggressive human lung adenocarcinoma (LADC), but its function remains…”
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Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease
Published in The Journal of immunology (1950) (15-02-2018)“…In the context of inflammation, osteopontin (Opn) is known to promote effector responses, facilitating a proinflammatory environment; however, its role during…”
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9
Can muscle protein metabolism be specifically targeted by exercise training in COPD?
Published in Journal of thoracic disease (01-05-2018)“…Patients with stable chronic obstructive pulmonary disease (COPD) frequently exhibit unintentional accentuated peripheral muscle loss and dysfunction. Skeletal…”
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10
ERβ-Dependent Direct Suppression of Human and Murine Th17 Cells and Treatment of Established Central Nervous System Autoimmunity by a Neurosteroid
Published in The Journal of immunology (1950) (01-10-2016)“…Multiple sclerosis (MS), an autoimmune disease of the CNS, is mediated by autoreactive Th cells. A previous study showed that the neurosteroid…”
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Increased Levels of Osteopontin in Sputum Supernatant in Patients With COPD
Published in Chest (01-10-2014)“…BACKGROUND Osteopontin (OPN) is a phosphorylated acidic glycoprotein that can function as both an extracellular matrix molecule and a cytokine. Published data…”
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12
Expression of intramuscular extracellular matrix proteins in vastus lateralis muscle fibres between atrophic and non-atrophic COPD
Published in ERJ open research (01-05-2024)“…Extracellular matrix (ECM) proteins are the major constituents of the muscle cell micro-environment, imparting instructive signalling, steering cell behaviour…”
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13
Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets
Published in Nature medicine (01-05-2007)“…Osteopontin (Opn) is important for T helper type 1 (T(H)1) immunity and autoimmunity. However, the role of this cytokine in T(H)2-mediated allergic disease as…”
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14
Skeletal muscle adaptations to interval training in patients with advanced COPD
Published in Chest (01-12-2005)“…To investigate the response to interval exercise (IE) training by looking at changes in morphologic and biochemical characteristics of the vastus lateralis…”
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15
Exercise Training-Induced Extracellular Matrix Protein Adaptation in Locomotor Muscles: A Systematic Review
Published in Cells (Basel, Switzerland) (26-04-2021)“…Exercise training promotes muscle adaptation and remodelling by balancing the processes of anabolism and catabolism; however, the mechanisms by which exercise…”
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16
Osteopontin Deficiency Protects against Airway Remodeling and Hyperresponsiveness in Chronic Asthma
Published in American journal of respiratory and critical care medicine (15-05-2009)“…Osteopontin (OPN) is a cytokine that is upregulated in epithelial cells and macrophages in the lungs of mice during chronic allergen challenge and airway…”
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17
Increased levels of osteopontin in sputum supernatant in severe refractory asthma
Published in Thorax (01-09-2010)“…Osteopontin (OPN) is a glycoprotein that has been associated with inflammation and fibrosis. Severe refractory asthma (SRA) is characterised by an intense…”
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18
Angiopoietin-1 Protects against Airway Inflammation and Hyperreactivity in Asthma
Published in American journal of respiratory and critical care medicine (15-06-2008)“…The angiopoietins (Ang) comprise a family of growth factors mainly known for their role in blood vessel formation and remodeling. The best-studied member,…”
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Vascular endothelial growth factor: an angiogenic factor reflecting airway inflammation in healthy smokers and in patients with bronchitis type of chronic obstructive pulmonary disease?
Published in Respiratory research (15-07-2007)“…Patients with bronchitis type of chronic obstructive pulmonary disease (COPD) have raised vascular endothelial growth factor (VEGF) levels in induced sputum…”
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Angiopoietins 1 and 2 in sputum supernatant of optimally treated asthmatics: the effect of smoking
Published in European journal of clinical investigation (01-01-2015)“…Background Angiopoietin‐1 (Ang‐1) is an essential mediator of angiogenesis by establishing vascular integrity, whereas angiopoietin‐2 (Ang‐2) acts as its…”
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