Search Results - "SIM, Malcolm"

The COVID-19 pandemic: major risks to healthcare and other workers on the front line by Sim, Malcolm R

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TCRs and AI: the future is now by Sim, Malcolm J. W.

“…A preprint by Fast et al. describes TAPIR, a computational tool for predicting TCR–pMHC interactions…”
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High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D by Sim, Malcolm J. W., Lu, Jinghua, Spencer, Matthew, Hopkins, Francis, Tran, Eric, Rosenberg, Steven A., Long, Eric O., Sun, Peter D.

“…Complete cancer regression occurs in a subset of patients following adoptive T cell therapy (ACT) of ex vivo expanded tumor-infiltrating lymphocytes (TILs)…”
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Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C by Sim, Malcolm J. W., Rajagopalan, Sumati, Altmann, Daniel M., Boyton, Rosemary J., Sun, Peter D., Long, Eric O.

“…Natural killer (NK) cells have an important role in immune defense against viruses and cancer. Activation of human NK cell cytotoxicity toward infected or…”
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T Cell Recognition of Tumor Neoantigens and Insights Into T Cell Immunotherapy by Sim, Malcolm J W, Sun, Peter D

“…In cancer, non-synonymous DNA base changes alter protein sequence and produce neoantigens that are detected by the immune system. For immune detection,…”
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Occupational heat stress and economic burden: A review of global evidence by Borg, Matthew A., Xiang, Jianjun, Anikeeva, Olga, Pisaniello, Dino, Hansen, Alana, Zander, Kerstin, Dear, Keith, Sim, Malcolm R., Bi, Peng

“…The adverse effects of heat on workers’ health and work productivity are well documented. However, the resultant economic consequences and productivity loss…”
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Ergonomic interventions for preventing work-related musculoskeletal disorders of the upper limb and neck among office workers by Hoe, Victor Cw, Urquhart, Donna M, Kelsall, Helen L, Zamri, Eva N, Sim, Malcolm R

“…Work-related upper limb and neck musculoskeletal disorders (MSDs) are one of the most common occupational disorders worldwide. Studies have shown that the…”
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The Effect of High-Flow Nasal Cannula Oxygen Therapy on Mortality and Intubation Rate in Acute Respiratory Failure: A Systematic Review and Meta-Analysis by Monro-Somerville, Thalia, Sim, Malcolm, Ruddy, James, Vilas, Mark, Gillies, Michael A.

“…OBJECTIVE:High-flow nasal cannulae are used in adults with or at risk of acute respiratory failure. We conducted a systematic review and meta-analysis to…”
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Exposure to wildfire-related PM2.5 and site-specific cancer mortality in Brazil from 2010 to 2016: A retrospective study by Yu, Pei, Xu, Rongbin, Li, Shanshan, Yue, Xu, Chen, Gongbo, Ye, Tingting, Coêlho, Micheline S. Z. S., Saldiva, Paulo H. N., Sim, Malcolm R., Abramson, Michael J., Guo, Yuming

“…Background Long-term exposure to fine particles ≤2.5 μm in diameter (PM 2.5 ) has been linked to cancer mortality. However, the effect of wildfire-related PM…”
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The Impact of Work Loss on Mental and Physical Health During the COVID-19 Pandemic: Baseline Findings from a Prospective Cohort Study by Griffiths, Daniel, Sheehan, Luke, van Vreden, Caryn, Petrie, Dennis, Grant, Genevieve, Whiteford, Peter, Sim, Malcolm R., Collie, Alex

“…Purpose To determine if losing work during the COVID-19 pandemic is associated with mental and physical health status. To determine if social interactions and…”
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HLA-F: A New Kid Licensed for Peptide Presentation by Sim, Malcolm J.W., Sun, Peter D.

“…HLA-F, a non-classical MHC molecule, is not known to present peptides. Dulberger et al. (2017) show that HLA-F contains a distinct peptide-binding groove and…”
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T cells discriminate between groups C1 and C2 HLA-C by Sim, Malcolm J W, Stotz, Zachary, Lu, Jinghua, Brennan, Paul, Long, Eric O, Sun, Peter D

“…Dimorphic amino acids at positions 77 and 80 delineate HLA-C allotypes into two groups, C1 and C2, which associate with disease through interactions with C1…”
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The Effect of Self-Efficacy on Return-to-Work Outcomes for Workers with Psychological or Upper-Body Musculoskeletal Injuries: A Review of the Literature by Black, Oliver, Keegel, Tessa, Sim, Malcolm R., Collie, Alexander, Smith, Peter

“…Purpose Work absence can result in substantial losses to the economy and workers. As a result, identifying modifiable factors associated with return-to-work…”
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Cancer and mortality in coal mine workers: a systematic review and meta-analysis by Alif, Sheikh M, Sim, Malcolm R, Ho, Clarence, Glass, Deborah C

“…Coal mine workers are exposed to a number of workplace hazards which may increase the risk of cancer and mortality. We conducted a systematic review and…”
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Estimation of RF and ELF dose by anatomical location in the brain from wireless phones in the MOBI-Kids study by Calderón, Carolina, Castaño-Vinyals, Gemma, Maslanyj, Myron, Wiart, Joe, Lee, Ae-Kyoung, Taki, Masao, Wake, Kanako, Abert, Alex, Badia, Francesc, Hadjem, Abdelhamid, Kromhout, Hans, de Llobet, Patricia, Varsier, Nadège, Conil, Emmanuelle, Choi, Hyung-Do, Sim, Malcolm R., Cardis, Elisabeth

“…[Display omitted] •Epidemiological studies on mobile phone radiation typically rely on phone use history.•MOBI-Kids is the first study to estimate RF and ELF…”
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Forest Fire Smoke Exposures and Out-of-Hospital Cardiac Arrests in Melbourne, Australia: A Case-Crossover Study by Dennekamp, Martine, Straney, Lahn D, Erbas, Bircan, Abramson, Michael J, Keywood, Melita, Smith, Karen, Sim, Malcolm R, Glass, Deborah C, Del Monaco, Anthony, Haikerwal, Anjali, Tonkin, Andrew M

“…Millions of people can potentially be exposed to smoke from forest fires, making this an important public health problem in many countries. In this study we…”
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Fine particulate matter (PM2.5) exposure during a prolonged wildfire period and emergency department visits for asthma by Haikerwal, Anjali, Akram, Muhammad, Sim, Malcolm R., Meyer, Mick, Abramson, Michael J., Dennekamp, Martine

“…Background and objective The 2006–2007 wildfire period was one of the most extensive and long lasting fires in Australian history with high levels of fine…”
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KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells by Sim, Malcolm J. W., Stowell, Janet, Sergeant, Ruhena, Altmann, Daniel M., Long, Eric O., Boyton, Rosemary J.

“…Killer cell immunoglobulin‐like receptor/HLA class I (KIR/HLA‐I) combinations are associated with disease risk, implicating functional roles for NK cells…”
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Loss of life expectancy from PM2.5 in Brazil: A national study from 2010 to 2018 by Yu, Pei, Xu, Rongbin, Li, Shanshan, Coelho, Micheline S.Z.S., Saldiva, Paulo H.N., Sim, Malcolm R., Abramson, Michael J., Guo, Yuming

“…[Display omitted] •PM2.5 was associated with reduced life expectancy from all-causes, cancer, cardiovascular and respiratory diseases.•Regional inequalities…”
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The effects of ambient temperatures on the risk of work-related injuries and illnesses: Evidence from Adelaide, Australia 2003–2013 by Varghese, Blesson M., Barnett, Adrian G., Hansen, Alana L., Bi, Peng, Hanson-Easey, Scott, Heyworth, Jane S., Sim, Malcolm R., Pisaniello, Dino L.

“…The thermal environment can directly affect workers’ occupational health and safety, and act as a contributing factor to injury or illness. However, the…”
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