Search Results - "SILVA, S. J"
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A relaxed constant positive linear dependence constraint qualification and applications
Published in Mathematical programming (01-10-2012)“…In this work we introduce a relaxed version of the constant positive linear dependence constraint qualification (CPLD) that we call RCPLD. This development is…”
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2
A Deep Learning Parameterization for Ozone Dry Deposition Velocities
Published in Geophysical research letters (28-01-2019)“…The loss of ozone to terrestrial and aquatic systems, known as dry deposition, is a highly uncertain process governed by turbulent transport, interfacial…”
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3
A Cascade of Cytokines Mediates Mechanical Inflammatory Hypernociception in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2005)“…The hypernociceptive effects of cytokines [TNF-α, keratinocyte-derived chemokine (KC), and IL-1β] and their participation in carrageenan (Cg)-induced…”
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Smart testing and critical care bed sharing for COVID-19 control
Published in PloS one (06-10-2021)“…During the early months of the current COVID-19 pandemic, social distancing measures effectively slowed disease transmission in many countries in Europe and…”
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Extending AAV Packaging Cargo through Dual Co-Transduction: Efficient Protein Trans-Splicing at Low Vector Doses
Published in International journal of molecular sciences (23-06-2023)“…Adeno-associated viral (AAV) vectors represent one of the leading platforms for gene delivery. Nevertheless, their small packaging capacity restricts their use…”
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Chemokines in Oral Inflammatory Diseases: Apical Periodontitis and Periodontal Disease
Published in Journal of dental research (01-04-2007)“…The inflammatory oral diseases are characterized by the persistent migration of polymorphonuclear leukocytes, monocytes, lymphocytes, plasma and mast cells,…”
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Myeloperoxidase inhibitor AZD5904 enhances human sperm function in vitro
Published in Human reproduction (Oxford) (18-02-2021)“…Abstract STUDY QUESTION Does AZD5904, a myeloperoxidase inhibitor (MPOi), have any effect on human sperm function in vitro? SUMMARY ANSWER AZD5904 improves…”
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Genotoxic and mutagenic effects of methyl ether dillapiole on the development of Aedes aegypti (Diptera: Culicidae)
Published in Medical and veterinary entomology (01-12-2021)“…Dillapiole, extracted from Piper aduncum essential oil and its derivatives, has been shown to be a potential alternative to the control of Aedes aegypti, which…”
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Improved virus purification processes for vaccines and gene therapy
Published in Biotechnology and bioengineering (01-05-2015)“…ABSTRACT The downstream processing of virus particles for vaccination or gene therapy is becoming a critical bottleneck as upstream titers keep improving…”
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Precipitation changes in the South American Altiplano since 1300 AD reconstructed by tree-rings
Published in Climate of the past (30-03-2012)“…Throughout the second half of the 20th century, the Central Andes has experienced significant climatic and environmental changes characterized by a persistent…”
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Assessing Multi-Attribute Characterization of Enveloped and Non-Enveloped Viral Particles by Capillary Electrophoresis
Published in Viruses (17-11-2022)“…Virus-based biopharmaceutical products are used in clinical applications such as vaccines, gene therapy, and immunotherapy. However, their manufacturing…”
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A crucial role for TNF‐α in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5
Published in British journal of pharmacology (01-10-2009)“…Background and purpose: Chemokines orchestrate neutrophil recruitment to inflammatory foci. In the present study, we evaluated the participation of three…”
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13
role of parasite persistence in pathogenesis of Chagas heart disease
Published in Parasite immunology (01-11-2009)“…Chagas disease (CD) is caused by the infection with the protozoan haemoflagellate Trypanosoma cruzi. This disease is still a great menace to public health, and…”
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Impact of smoking on inflammation: overview of molecular mechanisms
Published in Inflammation research (01-05-2011)“…Background Inflammation is a critical component of normal tissue repair, as well as being fundamental to the body’s defense against infection. Environmental…”
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Accelerated Development of AAV Purification Process Using a High-Throughput and Automated Crossflow System
Published in Separations (01-03-2024)“…Adeno-associated viruses (AAV) are currently predominant viral transfer tools for gene therapy, and efforts are being made to design faster and more efficient…”
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Adenovirus purification by two-column, size-exclusion, simulated countercurrent chromatography
Published in Journal of Chromatography A (20-06-2014)“…•Ad5 was purified by size-exclusion chromatography (SEC) in a 2-column open-loop SMB system.•Clearance of impurities, namely DNA and host cell protein (HCP),…”
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On the Size of the Safety Area around the Launch Trajectory of a Rocket
Published in Aerospace (01-09-2023)“…The safety zone around the flight path of a rocket is determined by the fall of debris in the case of an accidental explosion or commanded termination. The…”
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Transcriptional alterations related to neuropathology and clinical manifestation of Alzheimer's disease
Published in PloS one (07-11-2012)“…Alzheimer's disease (AD) is the most common cause of dementia in the human population, characterized by a spectrum of neuropathological abnormalities that…”
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Enhancing the predictability of complex rehabilitation with a removable CAD/CAM-fabricated long-term provisional prosthesis: A clinical report
Published in The Journal of prosthetic dentistry (2012)“…Implementing any definitive prosthetic treatment of the residual edentulous ridge involves several risks. The patient's expectations may not be completely…”
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Strict Constraint Qualifications and Sequential Optimality Conditions for Constrained Optimization
Published in Mathematics of operations research (01-08-2018)“…Sequential optimality conditions for constrained optimization are necessarily satisfied by local minimizers, independently of the fulfillment of constraint…”
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